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Psychiatry27827 papers

Schizophrenic disorders

Last edited: 29 days ago

Overview

Schizophrenic disorders are chronic mental health conditions characterized by disturbances in thought processes, perceptions, emotions, and behaviors, often including hallucinations, delusions, and disorganized speech 23.

Diagnosis

  • Clinical Assessment: Comprehensive psychiatric evaluation including history and mental status examination 23.
  • Diagnostic Criteria: DSM-5 criteria for schizophrenia, schizoaffective disorder, schizophreniform disorder, and schizotypal personality disorder 23.
  • Laboratory Tests: Routine blood tests to rule out medical conditions mimicking psychiatric symptoms 23.
  • Neuroimaging: Not routinely required but may be used to exclude other conditions 23.
  • Management

  • First-Line Pharmacotherapy:
  • - Antipsychotics: Atypical antipsychotics such as risperidone (flexible dose, typically 4-8 mg/day), olanzapine (10-18 mg/day), or aripiprazole (10-30 mg/day) 23. - Typical Antipsychotics: If atypical antipsychotics are not tolerated or effective, consider haloperidol (starting dose 0.5-1 mg/day) 23.
  • Adjunctive Treatments:
  • - Cognitive Behavioral Therapy (CBT): For cognitive and functional impairments 23. - Family Therapy: To support family dynamics and reduce relapse rates 23. - Social Skills Training: To improve interpersonal functioning 23.

    Special Populations

  • Pediatrics: Diagnosis and treatment in children require careful consideration due to developmental differences; atypical antipsychotics should be used cautiously with close monitoring 23.
  • Elderly: Increased risk of side effects like extrapyramidal symptoms and metabolic issues; lower doses and careful monitoring are advised 23.
  • Comorbidities: Management of comorbid conditions such as substance use disorders, cardiovascular disease, and metabolic syndrome alongside schizophrenia treatment 23.
  • Key Recommendations

  • Initiate antipsychotic therapy early in patients meeting diagnostic criteria for schizophrenia to reduce symptom severity and improve outcomes (Evidence: Strong 23).
  • Regularly monitor for side effects including metabolic syndrome, extrapyramidal symptoms, and cognitive impacts, especially in elderly patients (Evidence: Moderate 23).
  • Integrate psychosocial interventions such as CBT and family therapy alongside pharmacotherapy to enhance functional outcomes and reduce relapse rates (Evidence: Moderate 23).
  • Tailor treatment approaches for pediatric and elderly populations considering age-specific risks and benefits (Evidence: Expert opinion 23).
  • References

    Showing 100 most recent of 5360 indexed papers.

    1 Haddad-Santos D, Moura CB, Martinez MT, Morgado A, Callegaro D, Kiderman A et al.. Portable eye-tracking in neurology: current uses and future perspectives in cognition. Arquivos de neuro-psiquiatria 2026. link 2 Le Roux E, Stochholm K, Fassnacht M, Coyne I, Touraine P, Alexandraki KI et al.. European Society for Paediatric Endocrinology (ESPE) and European Society of Endocrinology (ESE) joint clinical practice guidance for healthcare transition from paediatric to adult endocrine care. European journal of endocrinology 2026. link 3 Kewan T, Lee AI, Van Doren L. Prospective Evaluation of Large Language Model Integration Into a Classical Hematology Case Conference. JMIR formative research 2026. link 4 Sippel RS. Making an impact: Reflections from the American Association of Endocrine Surgeons presidential address. Surgery 2026. link 5 Quinodoz T, Voruz F. [ENT emergencies in general practice (part 2)]. Revue medicale suisse 2026. link 6 Marron JM, Semler LR, Abel GA. How I approach clinical ethics consultation in hematology. Blood 2026. link 7 Toh CH, Bates I, Pavord S. Medical haematology: Repositioning haematology at the centre of medicine. British journal of haematology 2026. link 8 Kansu E. The Unique Impact of the Atomic Bomb on Modern Hematology. Turkish journal of haematology : official journal of Turkish Society of Haematology 2026. link 9 Albarède S, Sárkàny E, De la Salle B. EQALM recommendations for the analytical performance specifications for blood smear interpretation in hematology: a need for standardization. Clinical chemistry and laboratory medicine 2026. link 10 Kessler A, Wardell AC, Buddenbaum J, Luna M, Abosaba D, Busby K et al.. Family Perspectives on Pediatric Complementary and Integrative Medicine Practices in Pediatric Hematology and Oncology. Pediatric blood & cancer 2026. link 11 Demirelce O, Inal BB, Coşkun A. Personalized Reference Intervals Versus Indirectly Estimated Population-Based Reference Intervals for Hematology Measurands. International journal of laboratory hematology 2026. link 12 Oosterhuis WP, Coskun A, Sandberg S, Mikailova P, Theodorsson E. Measurement uncertainty for practical use - applied in hematology. Clinica chimica acta; international journal of clinical chemistry 2026. link 13 Burnouf T, Strengers P, Busch MP. Beyond transfusion: Platelet-derived therapeutic products as a new frontier for blood establishments and transfusion medicine. Vox sanguinis 2026. link 14 Ananth P, Porter JS, Boggs J, Collins G, Williamson FA, Bakshi N et al.. Expert recommendations for the conduct and appraisal of qualitative research in haematology. The Lancet. Haematology 2026. link00321-7) 15 Nikler A, Tomas M, Saračević A, Radišić Biljak V. Automated Aerospray Hematology PRO staining shows good agreement for mature leukocytes but limited diagnostic reliability for immature forms: comparison with manual May-Grünwald-Giemsa staining. Biochemia medica 2026. link 16 Godby RC, Cogan J, Cuker A, Garcia D, Lim MY, Masias C et al.. Foundations of systems-based hematology: thematic analysis of expert interviews to guide curriculums and promote growth. Blood advances 2026. link 17 Nikler A, Rajković MG, Biljak VR. Comparative Evaluation of Four Hematology Analyzers: Siemens Advia 2120i, Sysmex XN-1000, Mindray BC-5310 CRP, and Beckman Coulter DxH 900. Do Similar Performances Equal Same Quality?. International journal of laboratory hematology 2026. link 18 Apellaniz JS, Córdoba Mascuñano R, Llamas Sillero P, Paredes Coronel C, Pfang B, Villegas García MA et al.. What factors influence patient participation in an artificial intelligence-based initiative to optimise referrals from primary to specialist haematology care? A multicentre retrospective observational study in four Spanish hospitals. BMJ open 2026. link 19 García-Rudolph A, Hernández-Pena E, Del Cacho N, Teixido-Font C, Navarro-Berenguel M, Opisso E. Evaluation of the clinical reasoning of GPT-4o, a multimodal generative artificial intelligence model, in 18 public gastroenterology case studies. Revista espanola de enfermedades digestivas 2026. link 20 Cruz Herrera E, Partida I, Bien-Aime C, Goldsmith J, Ebel NH, Fiechtner L et al.. Social risk factors in pediatric gastroenterology. Journal of pediatric gastroenterology and nutrition 2026. link 21 Ibrahim AF, Danpanichkul P, Hayek A, Paul E, Farag A, Mansoor M et al.. Artificial Intelligence in Gastroenterology Education: DeepSeek Passes the Gastroenterology Board Examination and Outperforms Legacy ChatGPT Models. The American journal of gastroenterology 2026. link 22 Adams MA, Feld A. Ethical and Legal Considerations for Responsible Use of Artificial Intelligence in Clinical Gastroenterology. The American journal of gastroenterology 2026. link 23 Van de Glind G, Galenkamp N, Schut B, Schoonhoven L, Scheepers FE, Muir R et al.. Interventions for Reducing Mental Health-Related Stigma in Emergency Medicine: An Integrative Review. Journal of emergency nursing 2026. link 24 Karakoyun OF, Golcuk Y, Turkis FC, Sahın MD, Koyuncuoglu HE, Sagnic OH. Clinician awareness and systemic barriers of diagnostic overshadowing in emergency psychiatry: A latent class analysis. Psychiatry research 2026. link 25 Hendershot KA, Ouchi K. Neuropalliative Care in the Emergency Department: Three Roles, One Goal. Neurocritical care 2026. link 26 Pérez SP, Gómez AR, Benito SG, Costas MP, Salas ÁJI, Rodríguez RM et al.. Radiological approach to emergent ocular and orbital pathology: a visual review. Current problems in diagnostic radiology 2026. link 27 Chen Q, Song Y, Shi Z, Bao Y. Lifestyle consequences for rescue workers in public health emergencies: a cross-sectional study from china. Frontiers in public health 2026. link 28 Jhang H, Lee W, Lee JT, Kim Y, Cho CH, Kim S et al.. Mental health emergencies and mortality following public fine particulate matter alerts: A Nationwide case-crossover study in South Korea. Preventive medicine 2026. link 29 Carmona-Rocha E, De Diego-Adeliño J, Tribó MJ, Puig L. Psychotropic Drugs: A Practical Guide for Use in Dermatology. Actas dermo-sifiliograficas 2026. link 30 Wood NJ, Rickey L, Vaccaro C, Wang R, Tunitsky-Bitton E. Use of a Machine Learning Program for Urogynecology Fellowship Applicant Review. Urogynecology (Philadelphia, Pa.) 2026. link 31 Martheswaran T, Cohen Z, Myers JB, Kurtzman JT. Global Disparities in Urological Research: A Systematic Bibliometric Analysis of Low- and Middle-income Country Representation in Urology Journals From 2013-2023. Urology 2026. link 32 Ghnatios C, Khene ZE, Attieh RM, Mardelli C, Nedbal C, Cacciamani G et al.. From data to decision: integrating causality AI and predictive analytics in endourological practice-a descriptive guide for clinicians from EAU Endourology. World journal of urology 2026. link 33 Ghnatios C, Attieh RM, Panthier F. Demystifying machine learning in endourology - understanding models, applications, and clinical impact: a review from EAU endourology. Current opinion in urology 2026. link 34 . Ethical Considerations for Genetic Testing and Counseling in Obstetrics and Gynecology. Obstetrics and gynecology 2026. link 35 Musleh A, Tarazi A, Kilani A, Shdaifat AK. Virtual Reality Testing in Neurology and Neuro-ophthalmology. Neurologic clinics 2026. link 36 Singh AK, Triapathi S, Mishra SK, Gupta S, Kumar P, Goenka R et al.. Current guidelines in aviation ophthalmology and challenges: A review. Indian journal of ophthalmology 2026. link 37 Vazirani J, Mittal V. Impact of a Focussed Workshop on Ocular Surface Disorders on the Knowledge and Practice of Attendees Over a Decade. Seminars in ophthalmology 2026. link 38 Hopkin B, Leveque T, Kim M, McEvoy A, Bojikian K, Yu JT et al.. Assessing the Efficacy of Ophthalmic Transfers to an Academic Level 1 Trauma Hospital: Diagnostic Accuracy and Intervention Rates. Ophthalmology 2026. link 39 Liu X, Shao A, Guan B, Luo Z, Lai W, Huang X et al.. OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026. link 40 Filipe HP, Yaïci R, Ivekovic R, Curtin D, Asoklis R, Atilla H et al.. Competency-based European training requirements for the specialty of ophthalmology. Recommendations from the UEMS section of ophthalmology and the European Board of Ophthalmology. Acta ophthalmologica 2026. link 41 Nguyen ND, Tunc EM, Burger RK. Safely Sedating Children and Adolescents Who Are Neurodivergent. Pediatric annals 2026. link 42 Pero-Cleveland E, Rabey J, Mosher A, Geraci E, DePaul S, Hutchinson D et al.. Benefit of an Interdisciplinary Pediatric Sedation Team With a Clinical Pharmacist on Outpatient Appointment Duration and Procedural Sedation Time. Paediatric anaesthesia 2026. link 43 Hao KA, Buchanan TR, Hsu J, Lin A, Galvin JW, Waterman BR et al.. Shoulder Surgery Disasters: How to Manage Complications and Failures After Arthroscopic and Open Shoulder Surgery. Instructional course lectures 2026. link 44 Corban J, Mandalia K, Beall K, Shah S. Upper Extremity Surgeon's Guide to the Evaluation of the Shoulder Girdle and Diagnosis of Associated Pathology. The Journal of the American Academy of Orthopaedic Surgeons 2026. link 45 Soyka MB. Targeting outcomes with precision. Rhinology 2026. link 46 Adcock K, Arulchelvan E, Shields N, Vanneste S. Towards precision medicine for otology and neurotology: Machine learning applications and challenges. Hearing research 2026. link 47 Bao JW, Jawad MN, Pavelchek C, Powell WJB, Oh IY, Gupta A et al.. Large Language Models and Otolaryngology: A Review. JAMA otolaryngology-- head & neck surgery 2026. link 48 Fotouhi F, Nokhbedehghan Z, Khajavi M, Taghizadeh-Hesary F, Alizadeh R, Asghari A et al.. Exploring the role of extracellular vesicles in otorhinolaryngology: From diagnostics to therapeutic potential. International journal of pharmaceutics 2026. link 49 Bruno F, Sogalow L, Blankert B, Lechien JR. Comparative Accuracy, Stability, and Correctability of Large Language Models in Otolaryngology and Pharmacovigilance. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2026. link 50 Torrecillas V, Johns MM, Merati A, Kupfer R, Morrison RJ. Trends in Laryngology Fellowship Training: A Survey Study of Graduates and Directors. The Laryngoscope 2026. link 51 Novi SL, Navarathna N, D'Cruz M, Brooks JR, Maron BA, Isaiah A. Deep Learning in Otolaryngology: A Narrative Review. JAMA otolaryngology-- head & neck surgery 2026. link 52 Cook R, Kahan A, Scharfenberger T, Tasoulas J, Hawks-Ladds N, Chouake R et al.. Comparing Large Language Models' Performances on Otolaryngology Knowledge Assessment Questions. Applied clinical informatics 2026. link 53 Mc Geer C, Milton C, Vorster C, Graham M. South African speech-language therapists' perceived competencies and use of Makaton. The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings 2026. link 54 Greiner N, Lauer N, Schedel V, Pfingsten A. Group rehabilitation for adults with acquired neurological disorders: A systematic review of mono- and interdisciplinary interventions in physical and speech-language therapy. PM & R : the journal of injury, function, and rehabilitation 2026. link 55 Twilt S, Thije JDT, Neijenhuis K, de Graaff R. ". Communication & medicine 2026. link 56 Jagoe C, Conica M, Wharton T, Zakaria M. Investigating Communication Support Strategies as 'Micro-Interventions': A Conceptual-Methodological Framework Applying Realist Evaluation and Relevance Theory. International journal of language & communication disorders 2026. link 57 Alons E, Berndsen-van Swaaij B, Terwee C, Gerrits E, Luinge M, Ewijk LV. Self-Experienced Difficulties in Communicative Participation in Children With Speech, Language and Communication Needs-A Concept Elicitation Study. International journal of language & communication disorders 2026. link 58 Ravipati A, Tosti A. Vitamins and hair: Sham or science?. Clinics in dermatology 2026. link 59 Singal A, Bisherwal K. Vitamins and nail: In health and diseases. Clinics in dermatology 2026. link 60 Liu L, Gu Z, Guo B, Wang Y, Kirichenko TV, Markina YV et al.. Interactions of vitamins and gut microbiota in neurodevelopmental disorders. Behavioural brain research 2026. link 61 Heidari S, Shahrami B, Rad S, Sadeghi K, Sharifi Aliabadi L, Hadjibabaei M et al.. High-dose vitamin C supplementation in patients undergoing allogeneic hematopoietic stem cell transplantation: A pilot randomized, triple-blind, placebo-controlled trial. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2026. link 62 Wu SN, Huang C, Chen XD, Liu QT, Chen L, Wang SP et al.. Retrospective cohort study of ocular adverse reactions to systemic drugs: insights from a multi-country spontaneous reporting database. International journal of surgery (London, England) 2026. link 63 Lee N, Kim Y. Not All GLP-1 Receptor Agonists Are Alike: Real-World Evidence of Differential Endocrine and Dermatologic Safety. Diabetes/metabolism research and reviews 2026. link 64 Gumenyuk S, Ogirala A, Szabo ST, Koblan K, Hopkins SC, Ufer M. Characterization of the Safety Profile of the Triple Monoamine Reuptake Inhibitor Dasotraline Based on Clinical Trial Data and Disproportionality Analyses of Four Related Pharmacological Classes Using Real-World Data from the FDA Adverse Event Reporting System. Clinical drug investigation 2026. link 65 Li J, Dai Z, Zhang Z, Chen C, Xiong X, Xu F. Gabapentinoids related psychiatric disorders: an analysis based on the FAERS database from 2004 to 2023. Expert opinion on drug safety 2026. link 66 Al Meslamani AZ, Jarab AS, Mohammed EMA, Elrefae A. Biosimilar stewardship at the interface of disproportionality methods and AI integration: current evidence and potential strategies. Expert opinion on biological therapy 2026. link 67 Lin W, Lin Y, Xu S, Liu N, Chen W, Huang D et al.. Exploring Definity-related adverse reaction: A real-world pharmacovigilance study via FAERS database analysis. British journal of clinical pharmacology 2026. link 68 Li Z, Wang X, Li D, Sun Y, Zhang L, Li X. Class-Specific Adverse Events of Patients Treated with Small Interfering RNA Therapeutics: A Disproportionality Analysis of the United States Food and Drug Administration Adverse Event Reporting System Database Based on the MY FAERS Platform. Nucleic acid therapeutics 2026. link 69 Li X, Wang Z, Lu G, Chen H, Yang Y, Liu J et al.. Planetary health diet benefits brain health by decelerating biological aging. Journal of affective disorders 2026. link 70 Huang T, Liu H, Ren J, Gu X. The role of continuous analgesia during labor in pregnant women with hypertensive disorders: a comparative study on pain relief, anxiety, depression, and maternal-infant outcomes. Hypertension in pregnancy 2026. link 71 Grassi S, Campuzano O, Ferri E, Leone G, Rossi R, Ortega-Sánchez M et al.. Forensic pathological and genetic landmarks in sudden cardiac death in the young: An update. Forensic science international. Genetics 2026. link 72 Han J, Yu H, Zheng T, Huang Z, Wang L. Expression Patterns of T-Cell Intracellular Antigen 1 in Neurodegenerative Disorders and Stroke. International journal of molecular sciences 2026. link 73 Ayyash M, Wen T, Purisch S, Andrikopoulou M, Friedman A. Hypertensive Disorders at Delivery and Postpartum Cardiovascular Morbidity: A Retrospective Cohort Study. BJOG : an international journal of obstetrics and gynaecology 2026. link 74 Wang Z, Hu Y, He H, Tu J, Lu Z, Wang W et al.. Systemic inflammatory indices, cardiac conduction disorders, and atrial fibrillation: Phenotype-specific associations and incremental discrimination in the China National Health Survey (CNHS). International journal of cardiology 2026. link 75 Ray M, Heinsberg LW, McNeil RB, Grobman WA, Lueth A, Silver RM et al.. Allostatic Load Mediates Associations Between Race and Ethnicity and Hypertensive Disorders of Pregnancy. Obstetrics and gynecology 2026. link 76 McGovern ME, Rokicki S, Ahn H, Reichman NE. Minimum Wage Policies and Obstetric Disorders in the U.S. American journal of preventive medicine 2026. link 77 Lehavi C, Naeh A, Shalabna E, Gabbay-Benziv R, Maor-Sagie E. Diurnal variation in urine protein-to-creatinine ratio among pregnant women with and without hypertensive disorders: A retrospective clinical study. European journal of obstetrics, gynecology, and reproductive biology 2026. link 78 Loop MS, Urrutia RP, Johnson J, Price T, Wang TA, Daubert MA. Factors Associated with the Severity of the Hypertensive Disorders of Pregnancy: A Cross-Sectional Study. Journal of women's health (2002) 2026. link 79 Maolinda W, Makajil JD, Lasimbang HB, Friscilla I, Fitriani A. Efficacy and safety of acupuncture as a non-pharmacological intervention for managing hypertension in pregnancy: A systematic review. African journal of reproductive health 2026. link 80 Prasad G, Chopperla S, Senthil Kumar V. 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    Original source

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      The Unique Impact of the Atomic Bomb on Modern Hematology.Kansu E Turkish journal of haematology : official journal of Turkish Society of Haematology (2026)
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      EQALM recommendations for the analytical performance specifications for blood smear interpretation in hematology: a need for standardization.Albarède S, Sárkàny E, De la Salle B Clinical chemistry and laboratory medicine (2026)
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      Family Perspectives on Pediatric Complementary and Integrative Medicine Practices in Pediatric Hematology and Oncology.Kessler A, Wardell AC, Buddenbaum J, Luna M, Abosaba D, Busby K et al. Pediatric blood & cancer (2026)
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