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Cenesthopathic schizophrenia

Last edited: 4/10/2026

Overview

Cenesthopathic schizophrenia is a subtype of schizophrenia characterized by the presence of cenesthopathic symptoms, which are bizarre and distressing somatic sensations. These symptoms can be a prominent feature and may contribute to the overall symptom burden and functional impairment in individuals with schizophrenia.

Diagnosis

  • Diagnosis of schizophrenia is based on established criteria, such as those in the DSM-5 or ICD-10, which include the presence of characteristic psychotic symptoms.
  • Cenesthopathic symptoms are identified through detailed clinical interview and assessment, focusing on the nature, intensity, and distress caused by somatic sensations.
  • No specific diagnostic tests are recommended for cenesthopathic schizophrenia; diagnosis relies on clinical evaluation.
  • Management

  • Pharmacological treatment for schizophrenia, including the cenesthopathic subtype, typically involves antipsychotic medications.
  • First-generation and second-generation antipsychotics are used to manage positive, negative, and cognitive symptoms, which may indirectly alleviate cenesthopathic experiences 1.
  • Adjunctive therapies, such as psychotherapy and social skills training, may be beneficial in managing overall functioning and distress 1.
  • Key Recommendations

  • Clinical practice guidelines (CPGs) for schizophrenia treatment should be utilized to guide pharmacological management 1.
  • The application of CPGs in clinical practice involves selecting a pertinent guideline, using standardized clinical scales for assessment, and translating findings into clinical problems addressed by the guideline's recommendations 1.
  • Clinicians should develop methods to apply CPG recommendations to their clinical practice, assessing the degree to which recommendations are respected 1.
  • References

    1 Delessert D, Pomini V, Grasset F, Baumann P. [Clinical practice guidelines for the treatment of schizophrenia: from theory to practice]. L'Encephale 2007. link

    Original source

    1. [1]
      [Clinical practice guidelines for the treatment of schizophrenia: from theory to practice].Delessert D, Pomini V, Grasset F, Baumann P L'Encephale (2007)

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