Overview
Recurrent major depressive disorder is characterized by repeated episodes of depression. Management focuses on achieving remission of the current episode and preventing future episodes.Diagnosis
Diagnosis of recurrent major depressive disorder requires a history of at least two distinct major depressive episodes 1.
Assessment should include evaluation of current symptoms, history of past episodes, and risk factors for recurrence 1.Management
Treatment aims to achieve remission of the current episode and prevent relapse and recurrence 1.
Pharmacological treatment is a cornerstone of management for recurrent major depressive disorder 1.
Selection of antidepressant medication should consider efficacy, tolerability, and patient preference 1.
Maintenance treatment is crucial for preventing further episodes 1.
Duration of treatment should be individualized, with longer durations recommended for patients with recurrent episodes 1.Key Recommendations
Pharmacological treatment is recommended for depressive episodes and recurrent depressive disorder 1. (Evidence: Moderate)
Treatment should include assessment of efficacy, monitoring, and appropriate duration 1. (Evidence: Moderate)
Maintenance treatment is important for preventing future depressive episodes in patients with recurrent disorder 1. (Evidence: Moderate)References
1 Samochowiec J, Dudek D, Kucharska Mazur J, Murawiec S, Rymaszewska J, Cubała WJ et al.. Pharmacological treatment of a depressive episode and recurrent depressive disorder - guidelines of the Polish Psychiatric Association and the National Consultant for Adult Psychiatry. Psychiatria polska 2021. link