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Psychiatry10 papers

Active disintegrative psychoses

Last edited: 4/10/2026

Overview

Active disintegrative psychoses are a group of severe mental disorders characterized by a profound disruption in thought, perception, and behavior. These conditions are associated with significant impairments in social functioning and the ability to understand and attribute mental states to oneself and others 1.

Diagnosis

  • Patients with schizophrenia spectrum disorders demonstrate substantial impairments in spontaneous mentalizing, specifically in attributing intentionality and appropriateness to actions 1.
  • Deficits are also observed in interpreting goal-directed movements 1.
  • No significant differences were observed in random movement tasks 1.
  • Management

  • No management strategies are discussed in the provided abstracts.
  • Special Populations

  • No information is available on special populations in the provided abstracts.
  • Key Recommendations

  • Patients with schizophrenia spectrum disorders exhibit significant deficits in spontaneous mentalizing, particularly in the attribution of intentionality and appropriateness 1. (Evidence: Strong)
  • Impairments in spontaneous mentalizing contribute to difficulties in social functioning for individuals with schizophrenia spectrum disorders 1. (Evidence: Strong)
  • While deficits are noted in interpreting goal-directed movements, random movement tasks do not show significant differences in patients with schizophrenia spectrum disorders 1. (Evidence: Strong)
  • References

    1 Hajnal A, Csulak T, Hebling D, Farkas Borbásné K, Herold M, Berke G et al.. Spontaneous mentalizing in patients with schizophrenia spectrum disorders: a meta-analysis. Psychological medicine 2025. link

    Original source

    1. [1]
      Spontaneous mentalizing in patients with schizophrenia spectrum disorders: a meta-analysis.Hajnal A, Csulak T, Hebling D, Farkas Borbásné K, Herold M, Berke G et al. Psychological medicine (2025)

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