← Back to guidelines
Infectious Disease3 papers

Influenza with gastrointestinal tract involvement

Last edited: 4/10/2026

Overview

Influenza can involve the gastrointestinal tract, and there is evidence suggesting a bidirectional causal relationship between the gut microbiota and influenza infection 1. Changes in gut microbiota abundance are associated with influenza infection and the occurrence of influenza pneumonia 1.

Diagnosis

Management

  • The gut microbiota may play a causal role in influenza infection 1.
  • Special Populations

    Key Recommendations

  • There is a significant association between influenza infection and five bacterial taxa, with changes in seven gut microbiota causally related to influenza infection 1.
  • Seven bacterial taxa showed a significant association with the occurrence of influenza pneumonia 1.
  • A bidirectional causal connection between the gut microbiota and influenza is suggested by Mendelian randomization studies 1.
  • References

    1 Xu F, Gan X, Tao Y, Li D, Xie P, Liu F et al.. Association between gut microbiota and influenza: a bidirectional two-sample mendelian randomization study. BMC infectious diseases 2023. link

    Original source

    1. [1]
      Association between gut microbiota and influenza: a bidirectional two-sample mendelian randomization study.Xu F, Gan X, Tao Y, Li D, Xie P, Liu F et al. BMC infectious diseases (2023)

    HemoChat

    by SPINAI

    Evidence-based clinical decision support powered by SNOMED-CT, Neo4j GraphRAG, and NASS/AO/NICE guidelines.

    ⚕ For clinical reference only. Not a substitute for professional judgment.

    © 2026 HemoChat. All rights reserved.
    Research·Pricing·Privacy & Terms·Refund·SNOMED-CT · NASS · AO Spine · NICE · GraphRAG