Overview
Dietetic gastritis, often associated with dietetic microangiopathy (DM) in pigs, involves vascular damage potentially linked to altered nutrient metabolism despite seemingly adequate dietary intake of antioxidants like vitamin E and selenium. 12Diagnosis
Measure tissue concentrations of alpha-tocopherol (vitamin E) and selenium in affected organs (heart, liver, kidney). 12
Evaluate polyunsaturated fatty acid (PUFA) levels in affected tissues. 1
Assess glutathione peroxidase (GSH-Px) activity as a marker of antioxidant status, though its role appears limited in this condition. 1Management
Ensure adequate dietary intake of vitamin E, despite tissue levels being lower in affected animals, as dietary levels were high in both groups. 1
Selenium supplementation may not be necessary based on tissue selenium levels being comparable between affected and control pigs. 2
Monitor and manage underlying dietary factors contributing to altered nutrient metabolism without specific adjunctive treatments mentioned in the abstracts.Special Populations
No specific data provided for pregnancy, pediatrics, elderly, or comorbidities in the context of dietetic gastritis.Key Recommendations
Regularly assess tissue alpha-tocopherol levels in pigs suspected of dietetic microangiopathy despite adequate dietary intake, to identify potential metabolic alterations. (Evidence: Moderate) 1
Tissue selenium levels do not warrant routine supplementation in pigs with dietetic microangiopathy, as concentrations are similar to controls. (Evidence: Moderate) 2
Focus on optimizing dietary vitamin E content while considering potential metabolic inefficiencies in affected animals. (Evidence: Expert opinion)References
1 Rice DA, Kennedy S. Vitamin E, selenium, and polyunsaturated fatty acid concentrations and glutathione peroxidase activity in tissues from pigs with dietetic microangiopathy (mulberry heart disease). American journal of veterinary research 1989. link
2 Lindberg P, Tanhuanpää E, Schulman A, Garry-Andersson AS. Tissue selenium in pigs with dietetic microangiopathy (MAP, "mulberry heart"). Acta veterinaria Scandinavica 1972. link