Clinical Presentation
Six out of 55 patients exhibited imaging and laboratory findings indicative of SSC post-transplantation, characterized by multifocal dilatation and stricture affecting intrahepatic (100%), hilar (66.7%), and extrahepatic bile ducts [PMID:30377725].
Diagnosis
SSC was diagnosed based on newly developed biliary abnormalities with cholestasis, identified through CT showing multifocal small cyst-like lesions and MRCP revealing beaded appearances [PMID:30377725].
ERCP contributed significantly to the diagnosis of sclerosing cholangitis in two cases, suggesting its utility for confirming the condition [PMID:1247356].
Management
Sequential ERCP studies helped determine the appropriate timing and type of surgical intervention in one patient with sclerosing cholangitis [PMID:1247356].
Prognosis & Follow-up
The median survival time for patients with SSC following lung transplantation was found to be 4.6 months [PMID:30377725].
The authors suggest that ERCP is an accurate and noninvasive means for follow-up in cases of sclerosing cholangitis, highlighting its role in long-term management [PMID:1247356].
References
1 Kim HJ, Park MS, Son JW, Han K, Lee JH, Kim JK et al.. Radiological patterns of secondary sclerosing cholangitis in patients after lung transplantation. Abdominal radiology (New York) 2019. link 2 Ruskin RB, Katon RM, Bilbao MK, Smith F. Evaluation of sclerosing cholangitis by endoscopic retrograde cholangiopancreatography. Archives of internal medicine 1976. link
2 papers cited of 3 indexed.