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Dermatology1 paper

Infection of skin and/or subcutaneous tissue

Last edited: 4/10/2026

Overview

Infection of skin and/or subcutaneous tissue (SSTIs) encompasses a diverse range of conditions, from minor superficial infections to life-threatening infections such as necrotizing fasciitis 12. These guidelines emphasize the importance of clinical skills in promptly diagnosing SSTIs, identifying the pathogen, and administering effective treatments in a timely fashion 12.

Diagnosis

  • Clinical skills are crucial for promptly diagnosing SSTIs 12.
  • Identifying the pathogen is an important aspect of diagnosis 12.

    • Management

  • Administering effective treatments in a timely fashion is emphasized 12.
    • Recommendations are concordant with IDSA guidelines for methicillin-resistant Staphylococcus aureus* infections 12.

    Special Populations

  • The guidelines address the wide array of SSTIs that occur in immunocompromised hosts 12.

    • Key Recommendations

  • Prompt clinical diagnosis of skin and soft tissue infections (SSTIs) is essential 12. (Evidence: Strong)
  • Identification of the causative pathogen is important for guiding appropriate treatment 12. (Evidence: Strong)
  • Timely administration of effective treatments is emphasized for SSTIs 12. (Evidence: Strong)
  • Management strategies for SSTIs should address the specific needs of immunocompromised hosts 12. (Evidence: Strong)

    • References

    1 Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL et al.. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014. link 2 Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL et al.. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014. link

    Original source

    1. [1]
      Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. — Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2014)
    2. [2]
      Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America. — Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2014)
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