Overview
Precocious puberty is defined as the onset of secondary sexual characteristics before the age of 8 years in girls. Breast development is a key physical marker of puberty onset 1.Diagnosis
Early breast development (thelarche) before age 8 years is a key indicator 1.Management
No management information is available in the provided abstracts.Special Populations
Pregnancy: High maternal weight, primiparity, and early maternal weight gain are associated with an increased risk of early breast onset/development in offspring 1. Preterm birth is associated with late breast onset/development 1. Smoking in pregnancy, maternal hypertensive disorders, breastfeeding, diabetes, and small for gestational age infants had inconsistent results regarding their association with breast development 1. Maternal age at delivery, alcohol drinking, selected drug use during pregnancy, and low birth weight were not associated with breast development 1.Key Recommendations
High maternal weight, primiparity, and early weight gain were associated with an increased risk of early breast onset/development 1. (Evidence: Moderate)
Late breast onset/development was associated with preterm birth 1. (Evidence: Moderate)References
1 Dalmartello M, Chiaffarino F, Esposito G, Cipriani S, Ricci E, La Vecchia C et al.. A systematic review on maternal and perinatal factors influencing breast development. Early human development 2023. link