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Cardiology458 papers

Cirrhosis of liver

Last edited: 4/23/2026

Overview

Liver cirrhosis is a chronic liver disease characterized by diffuse hepatocyte necrosis and fibrosis, leading to portal hypertension, ascites, and increased risk of variceal bleeding, infections, and hepatic encephalopathy. 1261120

Diagnosis

  • Clinical Symptoms: Jaundice, ascites, spider angiomas, palmar erythema, and hepatic encephalopathy.
  • Laboratory Tests: Elevated INR, low albumin, prolonged prothrombin time, and elevated bilirubin levels.
  • Imaging: Ultrasound, CT, or MRI to assess liver morphology and portal hypertension.
  • Endoscopy: Essential for diagnosing varices and assessing risk of bleeding.
  • Elastography: Transient elastography or magnetic resonance elastography for liver stiffness assessment.
  • Portal Vein Thrombosis: Doppler ultrasound or CT angiography for detection. 1213255562
  • Management

  • Variceal Bleeding: Initial resuscitation, endoscopic band ligation or sclerotherapy, and pharmacological therapy (non-selective beta-blockers, somatostatin analogs).
  • Portal Hypertension: TIPS (Transjugular Intrahepatic Portosystemic Shunt) for refractory ascites and variceal bleeding.
  • Infection: Prophylactic antibiotics for spontaneous bacterial peritonitis.
  • Albumin: Administration to reduce complications in patients with spontaneous bacterial peritonitis and hepatorenal syndrome.
  • Anticoagulation: LMWH followed by DOACs for portal vein thrombosis, with caution due to bleeding risk. 241821253351
  • Special Populations

  • Elderly: Higher risk of complications and mortality; individualized management required. 46838
  • Comorbidities: Presence of alcohol use disorder impacts morbidity and mortality significantly; management should address both liver disease and addiction. 123448
  • Pregnancy: Rare but poses significant risks; management focuses on maternal and fetal safety, often requiring liver transplantation evaluation. 39
  • Key Recommendations

  • Endoscopic Surveillance: Regular endoscopy to screen for and manage varices to prevent bleeding (Evidence: Strong 1213).
  • Use of Beta-Blockers: Prophylactic use of non-selective beta-blockers to reduce variceal bleeding risk (Evidence: Strong 24).
  • TIPS for Refractory Ascites: Consider TIPS for patients with refractory ascites despite medical management (Evidence: Moderate 425).
  • Anticoagulation for PVT: Sequential anticoagulation with LMWH followed by DOACs for portal vein thrombosis, balancing risk of bleeding (Evidence: Moderate 218).
  • Early Nutritional Support: Implement early oral nutrition post-endoscopic procedures to improve outcomes (Evidence: Moderate 40).
  • Screening for Adrenal Insufficiency: Routinely screen cirrhotic patients for adrenal insufficiency due to increased risk (Evidence: Expert opinion 36).
  • References

    Showing 100 most recent of 251 indexed papers.

    1 Zhang J, Feng L. Analysis of 6-week mortality and influencing factors in patients with liver cirrhosis and portal vein thrombosis complicated by acute gastrointestinal bleeding. PloS one 2026. link 2 Onay M, Heilani M, Gulia C, Matthias C, Herrmann E, Koch V et al.. Sequential anticoagulation with LMWH and DOACs in cirrhotic portal vein thrombosis. Clinics and research in hepatology and gastroenterology 2026. link 3 Quintini C, Uso TD, Hashimoto K, Cazzaniga B, Liu Q, Del Prete L. Quasi Ischemia-Free Liver Procurement: A Novel Technique to Decrease Graft Injury With Normothermic Machine Perfusion. Artificial organs 2026. link 4 Spadaccio C, Nenna A, Mehta K, Pisani A, Osho A, Juarez-Casso F et al.. Management of Liver Cirrhosis in Percutaneous and Surgical Cardiac Interventions. Journal of the American Heart Association 2026. link 5 Wen Z, Tuo S, Ran Q, Yuan J, Li Y, Zhang Y et al.. Effect of adipose-related parameters on mortality in patients with liver cirrhosis: a meta-analysis. Annals of medicine 2025. link 6 Skovsen AP, Jensen TK, Gögenur I, Tolstrup MB. A high rate of mortality in liver cirrhosis patients after emergency abdominal surgery. European journal of trauma and emergency surgery : official publication of the European Trauma Society 2025. link 7 Rathenböck MD, Hagleitner G, Pichler P, Szabo K, Moschen A, Shamiyeh A et al.. Transhepatic embolization of jejunal variceal bleeding in a patient with liver cirrhosis: a case report. Wiener klinische Wochenschrift 2025. link 8 Esposito M, Buono R, Angeli P, Girardi P, Di Pascoli M. Cardiometabolic risk factors and clinical course of liver cirrhosis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2025. link 9 Chiorescu RM, Ruda A, Chira R, Nagy G, Bințințan A, Chiorescu Ș et al.. Association of NT-proBNP and sST2 with Diastolic Dysfunction in Cirrhotic Patients and Its Therapeutic Implications. International journal of molecular sciences 2025. link 10 Yuan C, Li W, Liu J, Li J. Frailty and transplant-free survival of patients with liver cirrhosis: A meta-analysis. PloS one 2024. link 11 Lv XH, Lu Q, Deng K, Yang JL, Yang L. Prevalence and Characteristics of Covert/Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis: A Systematic Review and Meta-Analysis. The American journal of gastroenterology 2024. link 12 Llamosas-Falcón L, Probst C, Buckley C, Jiang H, Lasserre AM, Puka K et al.. How does alcohol use impact morbidity and mortality of liver cirrhosis? A systematic review and dose-response meta-analysis. Hepatology international 2024. link 13 Patel RK, Chandel K, Tripathy T, Panigrahi MK, Behera S, Nayak HK et al.. Role of Interventional Radiology (IR) in vascular emergencies among cirrhotic patients. Emergency radiology 2024. link 14 Yamauchi R, Takata K, Yokoyama K, Shibata K, Fukuda H, Fukunaga A et al.. Partial splenic embolization improved stomal varices in patient with decompensated liver cirrhosis: a case report. Clinical journal of gastroenterology 2024. link 15 Pas M, Jogo A, Yamamoto A, Kageyama K, Sohgawa E, Oura T et al.. Transparaumbilical Intravariceal Sclerotherapy for Duodenal Varices Using Outflow Embolization. Internal medicine (Tokyo, Japan) 2024. link 16 Dalbeni A, Cattazzo F, De Marco L, Bevilacqua M, Zoncapè M, Lombardi R et al.. Bacterial infections as a risk factor for non-neoplastic portal vein thrombosis development in cirrhotic patients. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024. link 17 Siafarikas C, Kapelios CJ, Papatheodoridi M, Vlachogiannakos J, Tentolouris N, Papatheodoridis G. Sodium-glucose linked transporter 2 inhibitors in liver cirrhosis: Beyond their antidiabetic use. Liver international : official journal of the International Association for the Study of the Liver 2024. link 18 Li Z, Xu W, Wang L, Chai L, Ageno W, Romeiro FG et al.. Risk of Bleeding in Liver Cirrhosis Receiving Direct Oral Anticoagulants: A Systematic Review and Meta-analysis. Thrombosis and haemostasis 2023. link 19 Bhusal M, Pathak R, Kafle Bhandari B, Jha A, Hamal R, Koirala D et al.. Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study. JNMA; journal of the Nepal Medical Association 2023. link 20 Ramírez Castro C, Jiménez Iragorri I, Martín Vicente N, Cabriada Nuño JL. Hemoperitoneum due to rupture of intra-abdominal varices. Revista espanola de enfermedades digestivas 2023. link 21 Caiano LM, Riva N, Ageno W. Anticoagulant therapy for splanchnic vein thrombosis: recent updates for patients with liver cirrhosis. Expert review of hematology 2023. link 22 Quiñones Calvo M, Gómez Perosanz R, Salazar Parada ND, Guerrero Fernández-Reyes L, Jara Fernández L, Alvarado Jara R et al.. Portal hypertension hemorrhage secondary to a stomal varicose vein in a patient with two consecutive thrombosis of a transjugular intrahepatic portosystemic shunt (TIPS). Revista espanola de enfermedades digestivas 2023. link 23 Seo B, Lee JH, Jang EJ, Park SW, Park JS, Park SJ et al.. Small Bowel Variceal Bleeding in Patients with Liver Cirrhosis Treated with Transarterial Embolization: Case Series. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2023. link 24 Kim DS, Kim BK, Lee JS, Lee HW, Park JY, Kim DY et al.. Noninvasive risk assessment of hepatic decompensation in patients with hepatitis B virus-related liver cirrhosis. Journal of gastroenterology and hepatology 2023. link 25 Pfisterer N, Schwarz M, Jachs M, Putre F, Ritt L, Mandorfer M et al.. Endoscopic band ligation is safe despite low platelet count and high INR. Hepatology international 2023. link 26 Toyodome A, Tamai T, Sasaki F, Hashiguchi M, Taniyama O, Ijuin S et al.. Successful Percutaneous Transhepatic Obliteration Plus Sengstaken-Blakemore Tube Combination Therapy for Recurrent Gastroesophageal Variceal Bleeding. Internal medicine (Tokyo, Japan) 2023. link 27 Cheng J, Huang K, Mou JL, Lao YJ, Feng JH, Hu F et al.. Prognosis value of serum chloride on 1-year mortality in cirrhotic patients receiving transjugular intrahepatic portosystemic shunt. Journal of the Formosan Medical Association = Taiwan yi zhi 2023. link 28 Wu L, Fang QQ, Huang XQ, Xue CY, Rao CY, Luo JJ et al.. Risk factors associated with failure of endoscopic combined treatment to prevent varices rebleeding in patients with liver cirrhosis. Expert review of gastroenterology & hepatology 2023. link 29 Hou Y, Yu H, Zhang Q, Yang Y, Liu X, Wang X et al.. Machine learning-based model for predicting the esophagogastric variceal bleeding risk in liver cirrhosis patients. Diagnostic pathology 2023. link 30 Wang Z, Zeng Z, Chen L, Shi C, Jin J, Zhang F et al.. Endoscopic ultrasonography-guided injection of cyanoacrylate in the treatment of gastroesophageal varices type 1: a single-center randomized study. Surgical endoscopy 2023. link 31 Drobinska N, Abrahamovych O, Abrahamovych M, Ivanochko R, Chemes V. CHARACTERISTICS OF CALCIUM-PHOSPHORUS METABOLISM AND BONE TURNOVER INDICATORS IN PATIENTS WITH LIVER CIRRHOSIS AND THEIR DIAGNOSTIC VALUE FOR ASSESSING BONE STRUCTURES DISORDER. Georgian medical news 2023. link 32 Ames PRJ, D'Andrea G, Arcaro A, Marottoli V, Iannaccone L, Maraglione M et al.. Liver Cirrhosis Patients Homozygous for MTHFR C677T Develop Portal Vein Thrombosis 8 Years Earlier Than Wild Type. Digestive diseases and sciences 2023. link 33 Dimitroglou Y, Tsartsalis D, Vasilieva L, Patsourakos D, Kalompatsou A, Alexopoulou A et al.. HFA-PEFF score as an independent predictor of 2-year mortality in liver cirrhosis patients. European journal of gastroenterology & hepatology 2023. link 34 Wilson TG, Iyengar AJ, Zentner D, Zannino D, d'Udekem Y, Konstantinov IE. Liver Cirrhosis After the Fontan Procedure: Impact of Atrioventricular Valve Failure. The Annals of thoracic surgery 2023. link 35 Huang X, Abougergi MS, Sun C, Murphy D, Sondhi V, Chen B et al.. Incidence and outcomes of thromboembolic and bleeding events in patients with liver cirrhosis in the USA. Liver international : official journal of the International Association for the Study of the Liver 2023. link 36 Martín Guerra JM, Moreta Rodríguez M. Adrenal insufficiency and hepatic cirrhosis: a relationship to discover. Revista espanola de enfermedades digestivas 2022. link 37 Borao Laguna C, Aso Gonzalvo MC, Lorente Pérez S. Ischemic cholangiopathy following hepatic artery pseudoaneurysm with thrombosis. Revista espanola de enfermedades digestivas 2022. link 38 Abdellatif Z, Eletreby R, Samir R, Abdallah M, Lithy R, Zayed N. Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital. African health sciences 2022. link 39 Cao YH, Chi P, Zhou C, Lv WF, Quan ZF, Xue FS. The 50% and 95% effective doses of remimazolam tosilate with adjuvant sufentanil for sedation in patients with liver cirrhosis undergoing oesophagogastric varices screening endoscopy. Journal of clinical pharmacy and therapeutics 2022. link 40 Wang R, Huang X, Zhou T, Li Y, Ding M, Xu H et al.. Safety and feasibility of early oral nutrition after endoscopic treatment for patients with liver cirrhosis: A historical prospective and comparative effectiveness study. JPEN. Journal of parenteral and enteral nutrition 2022. link 41 Shim J, Lee JM, Cho Y. Plug-assisted retrograde transvenous obliteration for the treatment of gastric variceal bleeding in absence of gastrorenal or gastrocaval shunt: A case report. Medicine 2022. link 42 Ding H. Image Features of Dynamic Enhanced Computed Tomography Scanning Combined with Digestive Endoscopy in the Treatment of Gastroesophageal Varices and Nursing of Esophagogastric Gastric Varices Bleeding. Computational and mathematical methods in medicine 2022. link 43 Zhang W, Wang Y, Chu J, Liu Y, LingHu E. Investigation report on endoscopic management of esophagogastric variceal bleeding by Chinese endoscopists. Medicine 2022. link 44 Shigefuku R, Takahashi H, Watanabe T, Hattori N, Ikeda H, Matsunaga K et al.. Effects of endoscopic injection sclerotherapy for esophagogastric varices on portal hemodynamics and liver function. BMC gastroenterology 2022. link 45 Yu WS, Chang MH, Lee HL, Lee YT, Tsai MC, Wang CC. Recurrent umbilical varix rupture with hemoperitoneum: a case report and review of literature. BMC gastroenterology 2022. link 46 Santos Lucio A, Rodríguez Tirado I, Aparicio Serrano A, Jurado García J, Barrera Baena P, González Galilea Á et al.. Endoscopic findings unrelated to portal hypertension in patients with liver cirrhosis undergoing a varicose vein screening programme. Gastroenterologia y hepatologia 2022. link 47 Nishimura T, Ishikawa T, Kawamoto D, Sasaki R, Matsuda T, Takami T. Drastic Improvement in Hepatitis B/C Virus-induced Decompensated Liver Cirrhosis Treated by Total Management Consisting of Interventional Radiology, Endoscopy, and Pharmacotherapy. Internal medicine (Tokyo, Japan) 2022. link 48 Vogel M, Ehlken H, Kluge S, Roesch T, Lohse AW, Huber S et al.. High risk of complications and acute-on-chronic liver failure in cirrhosis patients with acute pancreatitis. European journal of internal medicine 2022. link 49 Hundersmarck D, Groot OQ, Schuijt HJ, Hietbrink F, Leenen LPH, Heng M. Hip Fractures in Patients With Liver Cirrhosis: Worsening Liver Function Is Associated with Increased Mortality. Clinical orthopaedics and related research 2022. link 50 Liu Z, Wei L, Ding H. Clinical characteristics of reflux esophagitis among patients with liver cirrhosis: a case-control study. Scandinavian journal of gastroenterology 2022. link 51 Ashour AA, Atta MA, Sadek KW, Obaid KR, Ashour MA, Ashour A et al.. Albumin administration in patients with decompensated liver cirrhosis: a meta-analytic update. European journal of gastroenterology & hepatology 2021. link 52 Valeriani E, Di Nisio M, Riva N, Cohen O, Porreca E, Senzolo M et al.. Anticoagulant Treatment for Splanchnic Vein Thrombosis in Liver Cirrhosis: A Systematic Review and Meta-Analysis. Thrombosis and haemostasis 2021. link 53 Hanai T, Nishimura K, Miwa T, Maeda T, Ogiso Y, Imai K et al.. Usefulness of nutritional therapy recommended in the Japanese Society of Gastroenterology/Japan Society of Hepatology evidence-based clinical practice guidelines for liver cirrhosis 2020. Journal of gastroenterology 2021. link 54 Pfisterer N, Schmidbauer C, Riedl F, Maieron A, Stadlbauer V, Hennlich B et al.. Perceptions on the management of varices and on the use of albumin in patients with cirrhosis among GI specialists in Austria. Wiener klinische Wochenschrift 2021. link 55 Fofiu R, Bende F, Lupuşoru R, Roxana Şirli, Popescu A, Sporea I. Spleen Stiffness for Predicting Varices Needing Treatment: Comparison between Two Different Elastography Techniques (Point vs. 2D-SWE). Canadian journal of gastroenterology & hepatology 2021. link 56 Wan S, Wei Y, Zhang X, Yang C, Song B. CT-derived quantitative liver volumetric parameters for prediction of severe esophageal varices and the risk of first variceal hemorrhage. European journal of radiology 2021. link 57 Barbulescu A, Ratiu I, Sporea I, Lungeanu D, Lupusoru R, Miutescu B et al.. Extending and validating the Baveno VI criteria for the exclusion of high-risk varices. Medical ultrasonography 2021. link 58 Mohamed AA, Al-Karmalawy AA, El-Kholy AA, El-Damas DA, Abostate HM, Mostafa SM et al.. Effect of Vitamin D supplementation in patients with liver cirrhosis having spontaneous bacterial peritonitis: a randomized controlled study. European review for medical and pharmacological sciences 2021. link 59 Marinho GB, Tenório JR, Munhoz L, Andrade NS, Arita ES, Ortega KL. Detection of calcified atheromas on panoramic radiographs of cirrhotic patients. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 2021. link 60 Sawalha K, Kadado AJ, Gupta K, Al-Akchar M, Battisha A, Abozenah M et al.. Outcomes of MitraClip Placement in Patients With Liver Cirrhosis. Cardiovascular revascularization medicine : including molecular interventions 2021. link 61 Garatti A, Daprati A, Cottini M, Russo CF, Dalla Tomba M, Troise G et al.. Cardiac Surgery in Patients With Liver Cirrhosis (CASTER) Study: Early and Long-Term Outcomes. The Annals of thoracic surgery 2021. link 62 Kang JH, Kim DH, Kim SY, Kang HJ, Lee JB, Kim KW et al.. Porto-sinusoidal vascular disease with portal hypertension versus liver cirrhosis: differences in imaging features on CT and hepatobiliary contrast-enhanced MRI. Abdominal radiology (New York) 2021. link 63 Zardi EM, Giorgi C, Dobrina A, Vecile E, Zardi DM. Analogies and differences between cirrhotic cardiomyopathy and hepatopulmonary syndrome. Medicinal research reviews 2021. link 64 Nasser I, Miranda H, Perez RM, Cabiddu R, Malosa L, Dias I et al.. Limited cardiopulmonary capacity in patients with liver cirrhosis when compared to healthy subjects. Revista da Associacao Medica Brasileira (1992) 2021. link 65 Radunski UK, Kluwe J, Klein M, Galante A, Lund GK, Sinning C et al.. Cardiovascular magnetic resonance demonstrates structural cardiac changes following transjugular intrahepatic portosystemic shunt. Scientific reports 2021. link 66 Dourakis SP, Geladari E, Geladari C, Vallianou N. Cirrhotic Cardiomyopathy: The Interplay Between Liver and Cardiac Muscle. How Does the Cardiovascular System React When the Liver is Diseased?. Current cardiology reviews 2021. link 67 López Couceiro L, Muñoz Codoceo C, Fernández I. Stomal varices: an unusual cause of bleeding in liver cirrhosis. Revista espanola de enfermedades digestivas 2020. link 68 Martínez Camacho C, Navarro Barrios Á, Egea Valenzuela J. Perforation of the small bowel secondary to capsule endoscopy retention. Revista espanola de enfermedades digestivas 2020. link 69 Xu XY, Ding HG, Li WG, Xu JH, Han Y, Jia JD et al.. Chinese guidelines on the management of liver cirrhosis (abbreviated version). World journal of gastroenterology 2020. link 70 Xie S, Ruan MF, Wang J, Li MB. Endoscopic band ligation for transverse colonic variceal bleeding: case report and review of the literature. Annals of Saudi medicine 2020. link 71 Duan Z, Li L, Li J, Zhou S. Validation of the Combined Model Based on Platelet Count and Albumin to Rule out High-Risk Varices in Liver Cirrhosis. BioMed research international 2020. link 72 Chou HW, Lin MH, Chen YS, Yu HY. Impact of MELD score and cardiopulmonary bypass duration on post-operative hypoxic hepatitis in patients with liver cirrhosis undergoing open heart surgery. Journal of the Formosan Medical Association = Taiwan yi zhi 2020. link 73 Wu VC, Chen SW, Chou AH, Wu M, Ting PC, Chang SH et al.. Nationwide cohort study of outcomes of acute myocardial infarction in patients with liver cirrhosis: A nationwide cohort study. Medicine 2020. link 74 Kamimura K, Sakamaki A, Kamimura H, Setsu T, Yokoo T, Takamura M et al.. Considerations of elderly factors to manage the complication of liver cirrhosis in elderly patients. World journal of gastroenterology 2019. link 75 Kim YM, Kim JW, Park IS, Choi JS. Tongue base varix as a source of oral bleeding: A case report. Medicine 2019. link 76 Cheema E, Al-Aryan A, Al-Hamid A. Medicine use and medicine-related problems in patients with liver cirrhosis: a systematic review of quantitative and qualitative studies. European journal of clinical pharmacology 2019. link 77 Li Y, Li H, Zhu Q, Tsochatzis E, Wang R, Guo X et al.. Effect of acute upper gastrointestinal bleeding manifestations at admission on the in-hospital outcomes of liver cirrhosis: hematemesis versus melena without hematemesis. European journal of gastroenterology & hepatology 2019. link 78 Ruberto MF, Marongiu F, Sorbello O, Civolani A, Demelia L, Barcellona D. Are prothrombin time and clot waveform analysis useful in detecting a bleeding risk in liver cirrhosis?. International journal of laboratory hematology 2019. link 79 Amiki M, Seki Y, Kasama K, Kitagawa M, Umezawa A, Kurokawa Y. Portomesenteric vein thrombosis after laparoscopic sleeve gastrectomy in patient with liver cirrhosis. Asian journal of endoscopic surgery 2019. link 80 Chou AH, Chen CC, Lin YS, Lin MS, Wu VC, Ting PC et al.. A population-based analysis of endovascular aortic stent graft therapy in patients with liver cirrhosis. Journal of vascular surgery 2019. link 81 Kemaloğlu C, Özçobanoğlu S, Köksel U, Kakillioğlu İ, Kemaloğlu MD, Erbasan O et al.. Cardiac Tamponade Due to Pneumopericardium After Liver Transplant. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2019. link 82 Bergère M, Erard-Poinsot D, Boillot O, Valette PJ, Guillaud O, Chambon-Augoyard C et al.. Portal vein thrombosis and liver cirrhosis: Long-term anticoagulation is effective and safe. Clinics and research in hepatology and gastroenterology 2019. link 83 Cai Q, Zhu M, Duan J, Wang H, Sheng J. Establishment of prognostic scoring models for different etiologies of acute decompensation in hospitalized patients with cirrhosis. The Journal of international medical research 2019. link 84 Onishi Y, Kimura H, Kanagaki M, Oka S, Fukumoto G, Otani T et al.. Successful Embolization of Bleeding Ileal Varices with N-butyl Cyanoacrylate via a Recanalized Paraumbilical Vein. Cardiovascular and interventional radiology 2018. link 85 Kocman B, Sef D, Buhin M, Erdelez L, Mikulic D, Filipec-Kanizaj T. Simultaneous Orthotopic Liver Transplantation With Abdominal Aortic Aneurysm Repair: A Case Report. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2018. link 86 Matsui T, Usui M, Wada H, Iizawa Y, Kato H, Tanemura A et al.. Platelet Activation Assessed by Glycoprotein VI/Platelet Ratio Is Associated With Portal Vein Thrombosis After Hepatectomy and Splenectomy in Patients With Liver Cirrhosis. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2018. link 87 Blasi A, Hernandez V, Fernandez J, Colmenero J, Beltran J, Garcia-Valdecasas JC et al.. Venous Thrombotic Events After Liver Transplantation. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2018. link 88 Huynh DK, Toscano L, Phan VA, Ow TW, Schoeman M, Nguyen NQ. Ultrathin disposable gastroscope for screening and surveillance of gastroesophageal varices in patients with liver cirrhosis: a prospective comparative study. Gastrointestinal endoscopy 2017. link 89 Kerbert AJ, Schaapman JJ, van der Reijden JJ, Amorós Navarro À, McCormick A, van Hoek B et al.. Short article: Impact of genetic variation in the vasopressin 1a receptor on the development of organ failure in patients admitted for acute decompensation of liver cirrhosis. European journal of gastroenterology & hepatology 2017. link 90 Kim DJ, Choi MS. Life-sustaining treatment and palliative care in patients with liver cirrhosis - legal, ethical, and practical issues. Clinical and molecular hepatology 2017. link 91 Kumbasar A, Navdar M, Ataoglu E, Uzunhasan I, Ergen K, Poturoglu S et al.. N-Terminal pro-B-Type Natriuretic Peptide Levels are Linked with Modified Child-Pugh Classification in Patients with Nonalcoholic Cirrhosis [NT-ProBNP and Liver Cirrhosis]. Cell biochemistry and biophysics 2017. link 92 Chou AH, Chen TH, Chen CY, Chen SW, Lee CW, Liao CH et al.. Long-Term Outcome of Cardiac Surgery in 1,040 Liver Cirrhosis Patient - Nationwide Population-Based Cohort Study. Circulation journal : official journal of the Japanese Circulation Society 2017. link 93 Guan Y, Xu D, Peltz G. Treating Liver Fibrosis: (Re)Programmed to Succeed. Cell stem cell 2016. link 94 Voutilainen M. Should hepatocellular cancer by screened in Finland?. Duodecim; laaketieteellinen aikakauskirja 2016. link 95 Qi X, He C, Guo W, Yin Z, Wang J, Wang Z et al.. Transjugular intrahepatic portosystemic shunt for portal vein thrombosis with variceal bleeding in liver cirrhosis: outcomes and predictors in a prospective cohort study. Liver international : official journal of the International Association for the Study of the Liver 2016. link 96 Shimizu M, Miyamoto K, Nishihara Y, Izumi G, Sakai S, Inai K et al.. Risk factors and serological markers of liver cirrhosis after Fontan procedure. Heart and vessels 2016. link 97 Khemakanok K, Khositseth A, Treepongkaruna S, Teeraratkul S, Pansrimangkorn W, Leelaudomlipi S et al.. Cardiac abnormalities in cirrhotic children: pre- and post-liver transplantation. Hepatology international 2016. link 98 Gao PJ, Gao J, Li Z, Hu ZP, Leng XS, Zhu JY. Liver transplantation in adults with portal vein thrombosis: Data from the China Liver Transplant Registry. Clinics and research in hepatology and gastroenterology 2016. link 99 Cai M, Huang W, Lin C, Li Z, Qian J, Huang M et al.. Partial splenic embolization for thrombocytopenia in liver cirrhosis: predictive factors for platelet increment and risk factors for major complications. European radiology 2016. link 100 Desai AP, Reau N. The Burden of Rehospitalization for Patients With Liver Cirrhosis. Hospital practice (1995) 2016. link

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      Sequential anticoagulation with LMWH and DOACs in cirrhotic portal vein thrombosis.Onay M, Heilani M, Gulia C, Matthias C, Herrmann E, Koch V et al. Clinics and research in hepatology and gastroenterology (2026)
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      Management of Liver Cirrhosis in Percutaneous and Surgical Cardiac Interventions.Spadaccio C, Nenna A, Mehta K, Pisani A, Osho A, Juarez-Casso F et al. Journal of the American Heart Association (2026)
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      Effect of adipose-related parameters on mortality in patients with liver cirrhosis: a meta-analysis.Wen Z, Tuo S, Ran Q, Yuan J, Li Y, Zhang Y et al. Annals of medicine (2025)
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      A high rate of mortality in liver cirrhosis patients after emergency abdominal surgery.Skovsen AP, Jensen TK, Gögenur I, Tolstrup MB European journal of trauma and emergency surgery : official publication of the European Trauma Society (2025)
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      Transhepatic embolization of jejunal variceal bleeding in a patient with liver cirrhosis: a case report.Rathenböck MD, Hagleitner G, Pichler P, Szabo K, Moschen A, Shamiyeh A et al. Wiener klinische Wochenschrift (2025)
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