Management
In a study of 15 patients, EUS-guided drainage achieved 100% technical success and 93.3% clinical success, with symptomatic improvement and resolution of fluid collections observed [PMID:34872899].
The median time between surgery and EUS-guided drainage was 10 days (range 5-32 days) in the study [PMID:34872899].
In patients undergoing pancreaticoduodenectomy, the isolated Roux loop method showed a lower incidence of Grade C fistula (7% vs 11.6%, p=0.137) [PMID:38811279].
For patients with a soft pancreas, the isolated loop technique significantly lowered the incidence of Grade C fistula (8.5% vs 18.3%, p=0.049) [PMID:38811279]. Similarly, in those with a pancreatic duct diameter less than 5mm, the reduction was also notable (9.8% vs 17.2%, p=0.036) [PMID:38811279].
The study found that the operative time was significantly shorter in the isolated loop group (438 min vs 478 min, p<0.001) [PMID:38811279].
Prognosis & Follow-up
The median hospital stay following EUS-guided drainage was 16 days (range 11-48 days) [PMID:34872899].
References
1 Wang L, Zhang Y, Chen B, Ding Y. Endoscopic Ultrasound-Guided Drainage in the Management of Postoperative Pancreatic Fistula After Partial Pancreatectomy. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2021. link 2 Jena SS, Mehta NN, Yadav A, Nundy S. Peri-operative outcomes of pancreaticoduodenectomy comparing an isolated Roux loop or single loop for reconstruction: An ambispective observational study. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2024. link
2 papers cited of 3 indexed.