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Palliative Care4 papers

Meige syndrome

Last edited: 4/15/2026

Overview

Meige syndrome, also known as hemifacial spasm, is characterized by involuntary contractions of facial muscles, typically affecting the eyelids and orbicularis oris muscles, often without a clear etiology 1.

Diagnosis

  • Clinical presentation of involuntary spasms of facial muscles, predominantly around the eyes and mouth 1.
  • No specific diagnostic tests; diagnosis is primarily clinical 1.
  • Management

  • First-line treatment: Botulinum toxin injections are the mainstay of treatment to alleviate muscle spasms 1.
  • Adjunctive measures: Lidocaine tape application prior to botulinum toxin injections significantly reduces pain during the procedure, enhancing patient comfort 1.
  • Special Populations

  • No specific recommendations provided for pregnancy, pediatrics, elderly, or comorbidities in the given abstracts 1.
  • Key Recommendations

  • Utilize lidocaine tape before botulinum toxin injections to reduce pain experienced by patients (Evidence: Moderate) 1.
  • Botulinum toxin injections remain the first-line pharmacological intervention for managing symptoms of Meige syndrome (Evidence: Expert opinion) 1.
  • References

    1 Onguchi T, Takano Y, Dogru M, Ono M, Tsubota K. Lidocaine tape (Penles) reduces the pain of botulinum toxin injection for Meige syndrome. American journal of ophthalmology 2004. link

    Original source

    1. [1]
      Lidocaine tape (Penles) reduces the pain of botulinum toxin injection for Meige syndrome.Onguchi T, Takano Y, Dogru M, Ono M, Tsubota K American journal of ophthalmology (2004)

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