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Neurology3 papers

Acute relapsing multiple sclerosis

Last edited: 4/10/2026

Overview

Acute relapsing multiple sclerosis (MS) is characterized by the emergence of new neurological deficits or the worsening of existing ones, followed by a period of partial or complete recovery 1. Early diagnosis and treatment are crucial for managing the disease course 1.

Diagnosis

  • Diagnosis of MS relies on demonstrating dissemination in space and time of lesions in the central nervous system 1.
  • Clinical presentation, MRI findings, and sometimes evoked potentials are used for diagnosis 1.
  • Management

  • Early treatment of MS is recommended to modify the disease course 1.
  • Specific treatment recommendations are not detailed in the provided abstract.
  • Key Recommendations

  • Recommendations for the early definition and early treatment of multiple sclerosis are provided by the Multiple Sclerosis Think Tank (GRESEP) 1.
  • The GRESEP recommendations were developed using a RAND/UCLA appropriateness-derived method involving a working group, a rating group, and a reading group 1.
  • The aim of the GRESEP is to provide recommendations in response to clinical questions raised when managing patients with multiple sclerosis 1.
  • (Evidence: Expert opinion)

    References

    1 Zéphir H, Bodiguel E, Bensa C, Blanc F, Laplaud D, Magy L et al.. Recommendations for a definition of multiple sclerosis in support of early treatment. Revue neurologique 2012. link

    Original source

    1. [1]
      Recommendations for a definition of multiple sclerosis in support of early treatment.Zéphir H, Bodiguel E, Bensa C, Blanc F, Laplaud D, Magy L et al. Revue neurologique (2012)

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