Pathophysiology
The contralesional SMA contributes to recovery from SMA syndrome by replacing the function of the lesioned hemisphere through sensorimotor network (SMN) remodeling [PMID:35507429].
Clinical Presentation
Patients often exhibit global or partial akinesia within 24 hours following resection of a glioma from the supplementary motor area, with recovery spanning weeks to months [PMID:35507429].
Prognosis & Follow-up
Recovery from SMA syndrome is prolonged by smaller regions of contralesional SMA activation preoperatively and by the onset of paralysis 7 days postoperatively [PMID:35507429].
References
1 Fang S, Li L, Weng S, Zhang Z, Fan X, Jiang T et al.. Increasing nodal vulnerability and nodal efficiency implied recovery time prolonging in patients with supplementary motor area syndrome. Human brain mapping 2022. link
1 papers cited of 3 indexed.