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Anesthesiology105 papers

Status migrainosus

Last edited: 4/14/2026

Overview

Status migrainosus refers to a prolonged migraine attack lasting longer than 72 hours, often requiring hospitalization due to severity and intractable nature 1.

Diagnosis

  • Persistent headache lasting >72 hours consistent with migraine criteria 1.
  • Exclusion of other secondary causes through neuroimaging and laboratory tests when indicated 1.
  • Utilization of standardized health status questionnaires to assess functional impact 3.
  • Management

  • First-line treatment includes intravenous antiemetics and abortive agents such as dihydroergotamine or magnesium sulfate 1.
  • Adjunctive treatments may involve corticosteroids for inflammation and supportive care measures 1.
  • Consideration of patient-reported outcomes using validated tools like HealthQuiz for monitoring response and functional status 3.
  • Special Populations

  • No specific guidelines provided for pregnancy, pediatrics, elderly, or comorbidities within the given abstracts 134.
  • Key Recommendations

  • Utilize comprehensive electronic health records for detailed patient monitoring, acknowledging potential bias towards sicker patients 1 (Evidence: Moderate).
  • Incorporate standardized health status assessments to evaluate treatment efficacy and patient functional outcomes 3 (Evidence: Moderate).
  • Employ validated utility measures to quantify the impact of status migrainosus on quality of life, aiding in clinical decision-making 2 (Evidence: Moderate).
  • References

    1 Weiskopf NG, Rusanov A, Weng C. Sick patients have more data: the non-random completeness of electronic health records. AMIA ... Annual Symposium proceedings. AMIA Symposium 2013. link 2 Bakker C, van der Linden S. Health related utility measurement: an introduction. The Journal of rheumatology 1995. link 3 Roizen MF, Coalson D, Hayward RS, Schmittner J, Thisted RA, Apfelbaum JL et al.. Can patients use an automated questionnaire to define their current health status?. Medical care 1992. link 4 Nelson EC, Berwick DM. The measurement of health status in clinical practice. Medical care 1989. link 5 Hawley TG. Weights and heights of Fijians from coastal and inland villages. The New Zealand medical journal 1978. link 6 Hall P, Axelsson G, Sebag J. Relationship between work environment and anamnestic health status. Use of predictors, indicators and indices for the evaluation of medical and environmental factors. Scandinavian journal of work, environment & health 1975. link

    Original source

    1. [1]
      Sick patients have more data: the non-random completeness of electronic health records.Weiskopf NG, Rusanov A, Weng C AMIA ... Annual Symposium proceedings. AMIA Symposium (2013)
    2. [2]
      Health related utility measurement: an introduction.Bakker C, van der Linden S The Journal of rheumatology (1995)
    3. [3]
      Can patients use an automated questionnaire to define their current health status?Roizen MF, Coalson D, Hayward RS, Schmittner J, Thisted RA, Apfelbaum JL et al. Medical care (1992)
    4. [4]
      The measurement of health status in clinical practice.Nelson EC, Berwick DM Medical care (1989)
    5. [5]
      Weights and heights of Fijians from coastal and inland villages.Hawley TG The New Zealand medical journal (1978)
    6. [6]

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