Overview
Critical illness polyneuropathy (CIP) is a syndrome characterized by progressive, predominantly motor, axonal neuropathy occurring in critically ill patients, often associated with multi-organ dysfunction and severe systemic inflammation. 1221Diagnosis
Management
Special Populations
Key Recommendations
References
Showing 100 most recent of 2460 indexed papers.
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Attracting Emergency Medicine-Trained Residents to Surgical Critical Care: The Implications From a Nationwide Survey of Emergency Medicine Trainees Interested in Critical Care. Critical care medicine 2026. link 6 Good RJ, Schwartz A, Mink R, Boyer DL, Rozenfeld RA, Kink RJ et al.. Validity Evidence for a Transport Medical Control Assessment Tool Using Simulated Interfacility Transport Calls. Academic pediatrics 2026. link 7 Bäckström D, Tommila M, Pedersen M, Lindner T, Kruse N, Larsen R. Defining Critical Emergency Medicine (CrEM): A Delphi Study From Scandinavia. Acta anaesthesiologica Scandinavica 2026. link 8 Yeretsian T, Viau-Lapointe J, Ashraf R, D'Souza R, Lapinsky SE. A core outcome set and reporting checklist for research on critically ill obstetric patients: An international consensus study. Acta obstetricia et gynecologica Scandinavica 2026. link 9 Lederman O, Chapman J, Fibbins H, Haywood D, Hart NH, Furzer B et al.. Role of exercise physiologists in mental health support and recovery: 2026 Exercise and Sports Science Australia (ESSA) Consensus Statement. British journal of sports medicine 2026. link 10 Godier A, Gouel-Chéron A, Lukaszewicz AC. Women in anaesthesia and critical care: a narrative review of their impact on patient care, research innovation, and team performance. Anaesthesia, critical care & pain medicine 2026. link 11 Akkar I, Dogan MH, Turgut ZI, Dikmeer A, Yilmaz Kars M, Kizilarslanoglu MC. Investigation of General Characteristics, Short and Long-Term Clinical Outcomes of Oldest Old (≥ 85 Years) Intensive Care Unit Survivors Transferred to a Geriatrics Ward. Geriatrics & gerontology international 2026. link 12 Meersseman P, Wilmer A, Langouche L. Abnormalities of liver function during critical illness. Current opinion in critical care 2026. link 13 Magee PM, Paquette E, Daniels LA, Sanchez-Pinto LN, Yehya N. The Association Between Neighborhood Factors and Early Organ Dysfunction in Children Who Are Critically Ill: A Retrospective Cohort Study. The Journal of pediatrics 2026. link 14 Shirode P, Beck T, Fuhrman DY, Dixon AM, Tran M, Pelletier JH et al.. Tandem Extracorporeal Blood Purification/Support Therapies in Critically Ill Children: A Literature Review. Critical care medicine 2026. link 15 Wang G, Lian H, Zhang H, Wang X, Zhang S, Ni X. Interferon-γ (IFNγ), a double-edge sword that affects prognoses in critically ill patients: A prospective study. Cytokine 2026. link 16 Dillon EC, Lee CM, Gan W, Charles D, Soliman G, Robison J. Nursing Home Ratings and Characteristics Predict Hospice Use Among Decedents With Serious Illnesses. Journal of the American Medical Directors Association 2026. link 17 Dobson KG, Chien YC, Carnide N, Smith PM, Mustard CA. Comparing Profiles of Mental Illness and Positive Mental Health Between Injured Workers and the General Working Population in Ontario. American journal of industrial medicine 2026. link 18 McGinigle KL, Menard MT, Doros G, Strong MB, Farber A, Conte MS. Editor's Choice - Association Between Anatomical Patterns of Arterial Occlusive Disease and Endovascular Outcomes in the BEST-CLI Trial Supports the Use of the Global Limb Anatomic Staging System. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2026. link 19 Khalaf Mahran GS, Mahdy Sayed MM, Al-Jabry MM, Alharbi HF, Abdelkader Reshia FA. Effect of the Intra-abdominal Pressure on the Risk of Delirium in Mechanically Ventilated Patients: Considerations for Critical Care Nursing Practice. Dimensions of critical care nursing : DCCN 2026. link 20 Sochet AA, Amankwah EK, Andalib V, Jaffray J, Male C, Faustino EV et al.. Enhanced trial efficiency of the novel "contemporaneous control recapture" parallel-cohort RCT design: Methods and application in the CRITICAL-Kids-TP trial. 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Damage-associated molecular patterns and coagulation. British journal of haematology 2026. link 26 Li Z, Lu F, Dai Y, Ji L, Huang H, He P et al.. A Multicentre Survey of Paediatric Critical Care Nurses' Awareness, Knowledge and Practice of Intra-Abdominal Hypertension and Abdominal Compartment Syndrome. Nursing in critical care 2026. link 27 Wang Y, Li D, Zhu L. Obesity Paradox in Critically Ill Patients: Do Patients with Critical Diseases Benefit from Obesity?. Obesity facts 2026. link 28 Pardo E, Futier E, Muller L, Besch G, Vardon-Bounes F, Kipnis E et al.. Management of new-onset atrial fibrillation in critically ill patients: A national multicenter prospective cohort. Anaesthesia, critical care & pain medicine 2026. link 29 Grewal S, Haider S, Madassery S. DVA: Updated Evidence, Techniques, and Management Post-Intervention. Techniques in vascular and interventional radiology 2026. link 30 Tewelde SZ, Adjei S. Tackling the Treachery of Tachycardia. Emergency medicine clinics of North America 2026. link 31 ZhangJian SJ, Niu KY, Chen CB, Seak CJ, Yen CC. Incidence of Adverse Events in Peripheral Intravenous Vasopressor Use: A Systematic Review and Meta-Analysis. JAMA network open 2026. link 32 Farooqui M, Cooke M, Pato CN, Pato MT. Understanding and characterizing the higher rates of medical comorbidities in serious mental illness. Journal of psychiatric research 2026. link 33 Ives JA, Park AN, Chao NT, Nagarsheth KH. Modified Frailty Index as a Predictor of Contralateral Amputation and Mortality After Primary Amputation in Patients With Critical Limb Ischemia. The American surgeon 2026. link 34 Darnell R, Broomhall J, Newell C, Gendall E, Harrison D, Rowan K et al.. Critical Illness Related Cardiac Arrest (CIRCA): a prospective investigation of the incidence and outcome of cardiac arrest within intensive care units in the United Kingdom. Resuscitation 2026. link 35 Tan TW, Dansey KD, Farber A, Doros G, Menard MT, Rosenfield K et al.. High rates of nonindex limb amputation in the Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) trial. Journal of vascular surgery 2026. link 36 Hart JP, Davies MG. Outcomes of Interventions to Salvage the Jailed Profunda Femoris in Recurrent Limb-Threatening Critical Ischemia. Annals of vascular surgery 2026. link 37 Coz Yataco A, Soghier I, Hébert PC, Belley-Cote E, Disselkamp M, Flynn D et al.. Transfusion of Fresh Frozen Plasma and Platelets in Critically Ill Adults: An American College of Chest Physicians Clinical Practice Guideline. Chest 2025. link 38 Hwang DY, Oczkowski SJW, Lewis K, Birriel B, Downar J, Farrier CE et al.. Society of Critical Care Medicine Guidelines on Family-Centered Care for Adult ICUs: 2024. Critical care medicine 2025. link 39 Hamilton DK, Gary JC, Scruth E, Anderson HL, Cadenhead CD, Oczkowski SJ et al.. Society of Critical Care Medicine 2024 Guidelines on Adult ICU Design. Critical care medicine 2025. link 40 Lewis K, Balas MC, Stollings JL, McNett M, Girard TD, Chanques G et al.. A Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Critical care medicine 2025. link 41 Moore AR, Zheng H, Ganesan A, Hasin-Brumshtein Y, Maddali MV, Levitt JE et al.. A consensus immune dysregulation framework for sepsis and critical illnesses. Nature medicine 2025. link 42 Sosah FK, Donkor ES. Microbial foodborne outbreaks in Africa: a systematic review. International health 2025. link 43 Faiz SA, Warner MT, Lazarus DR, Ong P, Proud KC, Dinh K et al.. Delivering a Regional Procedural Bootcamp for Incoming Pulmonary and Critical Care Medicine Fellows. Chest 2025. link 44 Richardson BR, Devlin MF, Zielke A. Who Wants to Fly? A Descriptive Analysis of Clinician Interest in a Career in Prehospital and Retrieval Medicine. Air medical journal 2025. link 45 Aluce LM, Cooper JJ, Emlet LL, Cohen ER, Ostrowski SJ, Wood GJ et al.. Bringing competency-based communication training to scale: A multi-institutional virtual simulation-based mastery learning curriculum for Emergency Medicine residents. Medical teacher 2025. link 46 Kozhevnikov D, Wong AH, Jubanyik K, Tu S, Ellman MS, Morrison LJ. Resident perceptions of a novel virtual serious illness communication skills curriculum incorporating medical management: qualitative analysis of participant group interviews. Annals of palliative medicine 2025. link 47 Hwai H, Ho YJ, Wang CH, Huang CH. Large language model application in emergency medicine and critical care. Journal of the Formosan Medical Association = Taiwan yi zhi 2025. link 48 Carvey MMT, Zumsteg DM, Omidvar AA, Hawkins-Zafarnia A, Hynes AM. Effectiveness of the Essential Critical Care Concepts in Emergency Medicine: Extracorporeal Membrane Oxygenation and Cardiovascular Devices Module Implementation. MedEdPORTAL : the journal of teaching and learning resources 2025. link 49 Chiu PW, Chu SC, Yang CH, Lee HF, Hung HM, Hsu HC. Peer-assisted learning in critical care: a simulation-based approach for postgraduate medical training. Medical education online 2025. link 50 Brown DE, Rosen CB, Roberts SE, Moneme A, Wirtalla C, Kelz RR. Postdischarge Mental Health Care and Emergency General Surgery Readmission for Patients With Serious Mental Illness. Annals of surgery 2025. link 51 Payán Ellacuria E, Astobiza AM. Using Electroconvulsive Therapy (ECT) in emergency clinical situations against patient's autonomy: A case study analysis. Bioethics 2025. link 52 Maheta BJ, Singh NK, Bergman J, Brown-Johnson CG, Gunturi A, Interrante N et al.. Perioperative Integration of Palliative Care and Urology for Patients With Serious Urologic Illness: A Qualitative Need Finding Inquiry. Journal of pain and symptom management 2025. link 53 Grillo-Ardila CF, Triana-Moreno LC, Sanabria-Rodríguez OO. Critical care medicine and intensive care in obstetrics: in search of a legacy. Revista colombiana de obstetricia y ginecologia 2025. link 54 Janke MJ, Taylor L, Mendez MP, Malone AM, McGowan A, Liu Y et al.. Improving Serious Illness Communication Skills in Obstetrics and Gynecology Residents: A Pilot Study. Journal of surgical education 2025. link 55 Romito BT, Alexander JC. The Role of Artificial Intelligence in Preoperative Assessment, Surgical Risk Stratification, and Predictive Analytics in Anesthesiology and Critical Care. Anesthesiology clinics 2025. link 56 Paprocka-Lipińska A, Damps M, Barsow S, Kosiba B. Futile therapy: a survey of Polish anaesthesiologists. 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Inhaled isoflurane for sedation of mechanically ventilated children in intensive care (IsoCOMFORT): a multicentre, randomised, active-control, assessor-masked, non-inferiority phase 3 trial. The Lancet. Respiratory medicine 2025. link00203-6) 70 Wu PY, Lee SY, Wong LT, Chao WC. Early deep sedation was associated with post-hospital one-year mortality in critically ill surgical patients: a propensity-matched retrospective cohort study. BMC anesthesiology 2025. link 71 Gao X, Gao C, Fang X, Ren L, Zhang H, Tang Y et al.. Fospropofol disodium versus Propofol for deep sedation in critically ill patients: a randomized pilot study. BMC anesthesiology 2025. link 72 Bouchereau E, Pruvost-Robieux E, Siami S, Chaffaut C, Bouglé A, Gavaret M et al.. Altered lower brainstem neurophysiological response is associated with mortality in deeply sedated critically ill patients. Intensive care medicine 2025. link 73 Chua IS, Berler A, Ninteau K, Bain PA, Fromme EK, Edelen M et al.. Patient-Centered Measures of Goal Concordance in Geriatrics and Palliative Care: A Scoping Review. JAMA network open 2025. link 74 Özdemir S, Altunok İ, Özkan A. Comparison of the Predictive Power of Blood Urea Nitrogen/Albumin, Lactate/Albumin, and C-reactive Protein/Albumin Ratios for Prognosis of Mortality in Critically Ill Geriatric Patients in the Emergency Department. The Journal of emergency medicine 2025. link 75 Shen J, Yan J, Xie J, Li L. Proposing a novel ABCDEF framework for managing critical illness in geriatrics: challenges and perspectives. Annals of medicine 2025. link 76 Beil M, Alberto L, Bourne RS, Brummel NE, de Groot B, de Lange DW et al.. ESICM consensus-based recommendations for the management of very old patients in intensive care. Intensive care medicine 2025. link 77 Angelo Marques Carizio F, do Vale de Souza I, de Oliveira AM, Corrêa Melo MM, Barbosa Zanetti MO, Rossi Varallo F et al.. 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Evaluation of Hypoxia Markers in Critically Ill Patients Categorized by Their Burden of Organ Dysfunction: A Novel Approach to Detect Pathophysiological and Clinical Relevance in a Secondary Analysis of a Prospective Observational Study. International journal of molecular sciences 2025. link 82 Filippini DFL, Jiang M, Kramer L, van der Poll T, Cremer O, Hla TTW et al.. Plasma H3.1 nucleosomes as biomarkers of infection, inflammation and organ failure. Critical care (London, England) 2025. link 83 Marmiere M, D'Amico F, Monti G, Landoni G. Mastering the Sequential Organ Failure Assessment Score: Critical Choices of Score Statistic, Timing, Imputations, and Competing Risk Handling in Major Trials-A Systematic Review. Critical care medicine 2025. link 84 Moreno R, Rhodes A, Ranzani O, Salluh JIF, Berger-Estilita J, Coopersmith CM et al.. Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)-2 Score: A Consensus Statement. 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