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Anesthesiology19 papers

Segmental hyperhidrosis

Last edited: 4/15/2026

Overview

Segmental hyperhidrosis, particularly palmar hyperhidrosis, involves excessive sweating localized to specific body segments, significantly impacting quality of life. Thoracic sympathectomy, often performed endoscopically, is considered highly effective for treating this condition. 12

Diagnosis

  • Clinical presentation of excessive sweating localized to palms.
  • No specific diagnostic tests; diagnosis is clinical.
  • Severity can be assessed subjectively by patient symptoms and quality of life impact. 12
  • Management

  • First-line treatment: Thoracic sympathectomy, specifically endoscopic techniques.
  • - Single-port endoscopic thoracic sympathectomy (ETS) under monitored anesthesia care. - ETS with flexible thoracoscopy under deep sedation without intubation.
  • Adjunctive treatments: Not explicitly detailed in provided abstracts; pharmacological options like anticholinergics or iontophoresis may be considered off-label. 12
  • Special Populations

  • Pediatrics: Not addressed in provided abstracts.
  • Elderly: Not addressed in provided abstracts.
  • Comorbidities: No specific guidance provided for patients with comorbidities; individualized surgical risk assessment recommended. 12
  • Key Recommendations

  • Consider single-port endoscopic thoracic sympathectomy (ETS) with flexible thoracoscopy under monitored anesthesia care for palmar hyperhidrosis, offering advantages in recovery and reduced hospital stay. (Evidence: Moderate) 1
  • ETS can be safely performed under deep sedation without intubation, minimizing invasiveness and maintaining patient stability. (Evidence: Moderate) 2
  • Evaluate individual patient suitability for endoscopic sympathectomy considering surgical risks and benefits, especially in special populations where data is limited. (Evidence: Expert opinion) 12
  • References

    1 Ning Y, Wang Y, Tao X, Tang H, Jiang J, Li Y et al.. Single-Port Endoscopic Thoracic Sympathectomy with Monitored Anesthesia Care: A More Promising Procedure for Palmar Hyperhidrosis. World journal of surgery 2015. link 2 Tang H, Wu B, Xu Z, Xue L, Li B, Zhao X. A new surgical procedure for palmar hyperhidrosis: is it possible to perform endoscopic sympathectomy under deep sedation without intubation?. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2014. link

    Original source

    1. [1]
      Single-Port Endoscopic Thoracic Sympathectomy with Monitored Anesthesia Care: A More Promising Procedure for Palmar Hyperhidrosis.Ning Y, Wang Y, Tao X, Tang H, Jiang J, Li Y et al. World journal of surgery (2015)
    2. [2]
      A new surgical procedure for palmar hyperhidrosis: is it possible to perform endoscopic sympathectomy under deep sedation without intubation?Tang H, Wu B, Xu Z, Xue L, Li B, Zhao X European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2014)

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