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Emergency Medicine1 paper

Infective corneal ulcer

Last edited: 4/10/2026

Overview

An infective corneal ulcer is an open sore on the cornea, the clear front part of the eye, caused by an infection. These ulcers can lead to significant vision loss if not treated promptly.

Diagnosis

  • Key diagnostic criteria include ocular pain, redness, photophobia, decreased vision, and a visible defect on the cornea 1.
  • Diagnostic tests may include slit-lamp examination with fluorescein staining to visualize the ulcer and cultures of corneal scrapings to identify the causative organism 1.
  • Management

  • Lubricants may reduce the risk of corneal injury in critically ill, sedated, and mechanically ventilated patients 1.
  • Polyethylene chambers may be more effective than eye ointment in preventing corneal injury in this population 1.
  • Special Populations

  • Interventions to prevent corneal injury are specifically discussed for critically ill, sedated, and mechanically ventilated patients 1.
  • Key Recommendations

  • Lubricants are recommended for preventing corneal injury in critically ill, sedated, and mechanically ventilated patients 1. (Evidence: Moderate)
  • Polyethylene chambers may be considered for preventing corneal injury in critically ill, sedated, and mechanically ventilated patients 1. (Evidence: Weak)
  • References

    1 do Prado PR, Silveira RCCP, Vettore MV, Fossum M, Vabo GL, Gimenes FRE. Nursing interventions to prevent corneal injury in critically ill sedated and mechanically ventilated patients: A systematic review of interventions. Intensive & critical care nursing 2023. link

    Original source

    1. [1]
      Nursing interventions to prevent corneal injury in critically ill sedated and mechanically ventilated patients: A systematic review of interventions.do Prado PR, Silveira RCCP, Vettore MV, Fossum M, Vabo GL, Gimenes FRE Intensive & critical care nursing (2023)

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