Management
In a case series of 6 patients with severe neurotrophic ulcers treated with topical RGTA (1 drop every second day), complete corneal epithelialization was achieved in 2 patients (33%) [PMID:26845313].
Complications
One patient in the study experienced corneal perforation despite treatment with RGTA [PMID:26845313].
Prognosis & Follow-up
None of the patients showed improvement in best-corrected visual acuity following RGTA therapy [PMID:26845313].
References
1 Arvola RP, Robciuc A, Holopainen JM. Matrix Regeneration Therapy: A Case Series of Corneal Neurotrophic Ulcers. Cornea 2016. link
1 papers cited of 3 indexed.