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Cardiology3508 papers

Pulmonary tumor embolism

Last edited: 4/23/2026

Overview

Pulmonary tumor embolism (PTE) refers to the obstruction of pulmonary arteries by tumor material, often metastatic, leading to significant hemodynamic compromise and increased mortality. It is a rare but severe complication in oncologic patients.

Diagnosis

  • Clinical Presentation: Symptoms include dyspnea, chest pain, and signs of right heart strain.
  • Imaging: CT pulmonary angiography (CTPA) is the gold standard for diagnosis, identifying characteristic filling defects.
  • D-Dimer: Useful for excluding PE in low-risk patients but may be less reliable in high-risk or cancer patients 144.
  • Echocardiography: Right ventricular dysfunction is a critical finding indicative of hemodynamic instability 23.
  • Risk Stratification Tools: Use of clinical prediction rules like the Geneva score or PERC rule, though their applicability in cancer patients may vary 44.
  • Management

  • Anticoagulation: Initial treatment with systemic anticoagulation (e.g., low molecular weight heparin transitioning to oral anticoagulants like rivaroxaban or apixaban) 1.
  • Thrombolysis: Catheter-directed thrombolysis (CDT) may be considered in intermediate-to-high risk cases, with careful selection based on patient stability and thrombus characteristics 1229.
  • Mechanical Thrombectomy: For massive or refractory cases, mechanical thrombectomy can be effective, particularly with devices like Penumbra Indigo Lightning Flash System 37.
  • Supportive Care: Management of right heart failure, oxygenation, and hemodynamic support as needed 33.
  • Monitoring: Regular assessment of right ventricular function and clinical status 23.
  • Special Populations

  • Pregnancy: Management requires careful consideration of teratogenic risks; options include systemic anticoagulation with close monitoring 13.
  • Elderly: Increased risk of complications; tailored risk stratification and treatment intensity based on frailty and comorbidities 68.
  • Comorbidities: Presence of obstructive sleep apnea (OSA) may impact outcomes; consider OSA management alongside PE treatment 56.
  • Key Recommendations

  • Initiate systemic anticoagulation promptly in diagnosed cases of PTE (Evidence: Strong 1).
  • Consider catheter-directed thrombolysis for intermediate-to-high risk patients with favorable anatomy and stability (Evidence: Moderate 12).
  • Regularly monitor right ventricular function using echocardiography to guide management decisions (Evidence: Moderate 23).
  • Tailor treatment intensity based on patient-specific factors such as frailty and comorbidities (Evidence: Expert opinion 68).
  • Evaluate and manage comorbidities like obstructive sleep apnea to improve outcomes (Evidence: Moderate 56).
  • References

    Showing 100 most recent of 3229 indexed papers.

    1 Creager MA, Barnes GD, Giri J, Mukherjee D, Jones WS, Burnett AE et al.. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 2026. link 2 Creager MA, Barnes GD, Giri J, Mukherjee D, Jones WS, Burnett AE et al.. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Journal of the American College of Cardiology 2026. link 3 Mohammad Alizade T, Karimi R, Kazemizadeh H, Khoshnam Rad N. Pulmonary thromboembolism in Glanzmann Thrombasthenia: a case report and systematic literature review. Annals of hematology 2026. link 4 Janata K, Lipa AJ, Merrelaar A, Merrelaar M, Azizi-Semrad U, Herkner H et al.. Enhancing Pulmonary Embolism Risk Stratification: The National Early Warning Score and its Integration into the European Society of Cardiology Classification. Thrombosis and haemostasis 2026. link 5 Alawad S, Al-Saeed N, Jarrar A, Wen S, Sharma S. Obstructive sleep apnea and outcomes in acute pulmonary embolism: A large-scale database study. PloS one 2026. link 6 Fan Q, Li F, Wang L, Li Z, Liu J. Association between obstructive sleep apnea with recurrent pulmonary embolism: a meta-analysis. Irish journal of medical science 2026. link 7 Fritzmann E, Yuen AD, Chang S, Yaqoob M, Kinninger A, Chung J et al.. Clinical features, management, and outcomes of right heart thrombi: a retrospective cohort study. Thrombosis research 2026. link 8 Cardi S, Barco S, Wolf S, Demelo-Rodríguez P, Pérez-Pinar M, Skride A et al.. Characteristics and outcomes of acute pulmonary embolism among patients with polyvascular, single-vascular or no atherosclerotic disease: insights from RIETE. Clinical research in cardiology : official journal of the German Cardiac Society 2026. link 9 Yankova K, Abu Mughli R, Oikonomou A, Tahaineh S, Kha LC, Maroun G et al.. Non-thrombotic pulmonary artery embolism: radiologic findings and literature review. Emergency radiology 2026. link 10 Bruno E, Kewenter M, Creusen AD, Einarsson F, Perchiazzi G, Svennerholm K et al.. Computed Tomography Yield and Predictors of Pulmonary Embolism in Mechanically Ventilated Patients-A Retrospective Study. Acta anaesthesiologica Scandinavica 2026. link 11 Tukiendorf A, Feusette P. Does C-reactive protein exhibit high prognostic information value in acute pulmonary embolism? A novel structural pathway for disease progression beyond classical statistical associations. PloS one 2026. link 12 Gonsalves CF, Stortecky S, Horr S, Pappas O, Gandhi RT, Pereira K et al.. Evaluation of Catheter-Directed Thrombolysis Device Type and Dosing on Treatment Outcomes in Intermediate-Risk Pulmonary Embolism: A PEERLESS Randomized Controlled Trial Post Hoc Analysis. Journal of vascular and interventional radiology : JVIR 2026. link 13 Ye Y, Mahati S, Aihemaiti W, Lu G, Ding Y, ABuLaiTi B et al.. A postpartum-adapted algorithm for safe management of suspected pulmonary embolism: a retrospective cohort study. American journal of obstetrics and gynecology 2026. link 14 Fan Z, Lu J, Ye X, Deng X, Zhang Z. Swirl-inducing innovations for preventing vena cava filter blockage: Theoretical and experimental validation. Computer methods and programs in biomedicine 2026. link 15 Cedeño-Rodriguez FX, Hess Arcelay HW, Acosta Julbe JI, Varas-Rodríguez E, Cruz J, Otero F et al.. Pulmonary embolism following bilateral quadriceps tendon repair with unilateral tourniquet use: A case report. Journal of perioperative practice 2026. link 16 Kline JA, Ellison AM, Kuppermann N. Scoping review of the literature supporting the exclusion of pulmonary embolism without radiation in children. Expert review of respiratory medicine 2026. link 17 Afşin H, Afşin E. The role of ventilation/perfusion scintigraphy in distinguishing acute from chronic pulmonary embolism. Emergency radiology 2026. link 18 Lookstein RA, Konstantinides SV, Weinberg I, Dohad SY, Rosol Z, Kopeć G et al.. Randomized Controlled Trial of Mechanical Thrombectomy With Anticoagulation Versus Anticoagulation Alone for Acute Intermediate-High Risk Pulmonary Embolism: Primary Outcomes From the STORM-PE Trial. Circulation 2026. link 19 Anan H, Hayek PE, Alie-Cusson F, Min LX, Andraska E, Jadi J et al.. Catheter-directed interventions versus surgical embolectomy in massive pulmonary embolism. Journal of vascular surgery. Venous and lymphatic disorders 2026. link 20 Amini E, Hille G, Hürtgen J, Surov A, Saalfeld S. Deep learning-based segmentation of acute pulmonary embolism in cardiac CT images. International journal of computer assisted radiology and surgery 2026. link 21 Pathak P, Patel S, Reddy A, Mathew J, Basu A, Thiriveedi M et al.. Pulmonary Embolism and Right Heart Failure Associated With Lipomatous Atrial Septal Hypertrophy: A Case Report. The American journal of case reports 2026. link 22 Bonnefoy PB, Tromeur C, Bertoletti L, LE Roux PY. Role and interpretation of lung scintigraphy for long-term management of pulmonary embolism. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 2026. link 23 Cimini LA, Pruszczyk P, Jiménez D, Weekes A, Zuin M, Vanni S et al.. Right ventricular dysfunction on echocardiography to predict mortality in acute pulmonary embolism: an individual patient data meta-analysis. Journal of thrombosis and haemostasis : JTH 2026. link 24 Ehrhardt L, Fiedler P, Surov A, Saalfeld S. Prognostic potential of radiomics evaluation of lung artery thrombus for pulmonary embolism patients. International journal of computer assisted radiology and surgery 2026. link 25 Farmakis IT, Binder H, Chopard R, Christodoulou KC, Evrenoglou T, Fengler K et al.. Reperfusion strategies for acute pulmonary embolism: Design and rationale of RECONNECT-PE-A living systematic review and meta-analysis. American heart journal 2026. link 26 Huyut MT, Velichko A, Belyaev M, Izotov Y, Tosun M, Sertoğullarından B et al.. Clinical decision support system for detecting right ventricular dysfunction in acute pulmonary embolism: Explainable a new Binary Rule Search (BRS) ensembles and robustness evaluation. Artificial intelligence in medicine 2026. link 27 Iannaccone M, Sławek-Szmyt S, Gamardella M, Fumarola F, Mangione R, Savio D et al.. The role of Pulmonary Artery Pulsatility Index to assess the outcomes following catheter directed therapy in patients with intermediate-to-high and high-risk pulmonary embolism. Cardiovascular revascularization medicine : including molecular interventions 2026. link 28 Yin P, Abikhzer G, Zuckier LS. Radionuclide lung scintigraphy in the evaluation of suspected acute and chronic pulmonary embolism: methods, interpretation, and lexicon. A basic user guide for the clinician. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 2026. link 29 Pot L, Cassiani-Ingoni E, Gainnier M, Carvelli J, Boucekine M, Moyse P et al.. Catheter-directed versus standard therapy in intermediate-high-risk pulmonary embolism: A retrospective cohort study. Archives of cardiovascular diseases 2026. link 30 Moini C, Monchi M, Ramamourthy U, Awede R, Cabot B, Hraiech K et al.. Effect of half-dose thrombolysis on hypoxemia duration in intermediate risk pulmonary embolism. Journal of thrombosis and thrombolysis 2026. link 31 Mehta A, Bansal M, Patel J, Pillai A, Ingrassia JJ, de Klerk PS et al.. Body Mass Index and In-Hospital Management and Outcomes of Pulmonary Embolism: A Nationwide Analysis. Critical pathways in cardiology 2026. link 32 Ishida K, Nishimoto Y, Ohbe H, Ikeda N, Sugiura T, Suda R et al.. Short-term outcomes of thrombolysis versus surgical pulmonary embolectomy in patients with high-risk pulmonary embolism. The Journal of thoracic and cardiovascular surgery 2026. link 33 Babacan Ö, Karkaş AY, Durak G, Uysal E, Durak Ü, Shrestha R et al.. Deep Learning-based Automated Detection of Pulmonary Embolism: Is It Reliable?. Journal of computer assisted tomography 2026. link 34 Talerico R, de Wit K, Barco S, Bonorino J, Uil CD, Kraemer CE et al.. Evidence-based risk stratification of patients with acute pulmonary embolism: communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease. Journal of thrombosis and haemostasis : JTH 2026. link 35 Gloor M, Stalder O, Tritschler T, Méan M, Rodondi N, Righini M et al.. Comparison of easy-to-use clinical prognostic models to identify low-risk normotensive patients with pulmonary embolism. Journal of thrombosis and haemostasis : JTH 2026. link 36 Kjaergaard J, Bang LE, Sonne-Holm E, Wiberg S, Holmvang L, Lassen JF et al.. Randomized trial of low-dose, ultrasound-assisted thrombolysis or heparin for pulmonary embolism. Cardiovascular research 2026. link 37 Coutas T, Mannarino M, Ventura M, Fay J, Simões R, Mannarino G. Technical Aspects of Penumbra Indigo Lightning Flash System for Mechanical Thrombectomy of Pulmonary Embolism: A Comprehensive Review. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 2026. link 38 S S, Pradhan A, Kadavigere R, Dkhar W, Sukumar S, Barnes NA et al.. Reduction of radiation dose and contrast volume in CT pulmonary angiography: A systematic review and meta-analysis. Journal of medical imaging and radiation sciences 2026. link 39 Roto D, Haight D, Norton K, White RJ, Lachant D. Functional recovery after pulmonary embolism: A pilot study using metabolic monitoring during the 6-minute walk test. Respiratory medicine 2026. link 40 Fumagalli RM, von Stempel C, Pleming W, Klok FA, Konstantinides SV, Kucher N et al.. Comparative outcomes of ultrasound-assisted catheter-directed thrombolysis between patients with acute and acute-on-chronic pulmonary embolism. Thrombosis research 2026. link 41 Schwertner A, McMenamy J, Kerchberger J, Wallace G, Baird J, Naeger DM. Evaluation of artificial intelligence detection of pulmonary embolism in dual-energy computed tomography. Clinical radiology 2026. link 42 Deng Z, Luo D, Zhou J, Zhang X, Ren H, Deng W et al.. Thoracic muscle loss increases the use of mechanical ventilation in elderly patients with pulmonary embolism: constructing and validating a machine learning model on a two-center cohort. BMC geriatrics 2026. link 43 Ingemann-Molden S, Caspersen CK, Rolving N, Højen AA, Klok FA, Grove EL et al.. Psychometric properties of patient-related outcome measures used for patients surviving a pulmonary embolism: A systematic review. Thrombosis research 2026. link 44 Hara T, Adinata A, Suzuki Y, Asakura J, Emoto N. Application of murine hindlimb deep vein thrombosis model to assess temporal evolution and hemodynamic sequelae of pulmonary embolism. Biochemical and biophysical research communications 2026. link 45 Zhang Y, Wang L, Yuan D, Qi K, Zhang M, Zhang W et al.. Clinical value of the 70-kVp ultra-low-dose CT pulmonary angiography with deep learning image reconstruction. European radiology 2026. link 46 Noda H, Yutani C, Takahashi S, Takewa M, Iwa N, Kobayashi M et al.. Morphological Visualization of Thrombi During Catheter-Directed Fibrinolytic Therapy for Pulmonary Thromboembolism. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2026. link 47 Stammen L, Hoeijmakers EJI, Flohr TG, Gietema HA, Vandewall J, Wildberger JE et al.. Reducing contrast media dosage for pulmonary embolism CTPA in PCD-CT: a comparative study of EID-CT and PCD-CT in the era of individualized protocolling. European radiology 2026. link 48 Gunning SGS, Page J, Rossdale J, Charters PFP, Hudson B, Lyen S et al.. Artificial intelligence to improve the detection and risk stratification of acute pulmonary embolism (AID-PE): protocol for a pragmatic quasi-experimental comparator study. BMJ open 2026. link 49 Ekici M, Ekici A, Yılmaz S. Parenchymal opacities associated with pulmonary embolism. Respiratory medicine 2026. link 50 Adams R, Ramos C, McDaniel M. Pulmonary Embolism in a Patient With Interrupted Inferior Vena Cava With Azygos Continuation and Polysplenia: A Case Report and Literature Review. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2026. link 51 Chatani R, Yamashita Y, Morimoto T, Muraoka N, Shioyama W, Shibata T et al.. Home Treatment for Active Cancer Patients With Low-Risk Pulmonary Embolism - A Predetermined Companion Report From the ONCO PE Trial. Circulation journal : official journal of the Japanese Circulation Society 2026. link 52 Phillips DB, James MD, Vincent SG, Smyth RM, Chau B, Darko CA et al.. Acute effects of inhaled nitric oxide on inspiratory neural drive, dyspnea, and exercise endurance in symptomatic patients post-pulmonary embolism. Journal of applied physiology (Bethesda, Md. : 1985) 2026. link 53 Klok FA, Sharp A, Ahrens I, Aleksic M, Ni Ainle F, Barco S et al.. Rationale for and approach to establishing a multidisciplinary acute pulmonary embolism expert care team. European heart journal. Acute cardiovascular care 2026. link 54 Mayfield CK, Lechtholz-Zey EA, Ayad M, Craig DW, Della Valle CJ, Parvizi J et al.. Whole-Exome Sequencing of Total Joint Arthroplasty Patients Who Have Known Pulmonary Embolism: A Pilot Study. The Journal of arthroplasty 2026. link 55 Mai V, Takada T, Kraaijpoel N, van Es N, Mallick R, Stals MAM et al.. Safety and efficiency of diagnostic strategies for ruling out pulmonary embolism in patients with chronic lung disease: an individual-patient data meta-analysis. Journal of thrombosis and haemostasis : JTH 2026. link 56 Kim C, Choi H, Shim E, Kim J, Hwang SH, Yong HS et al.. Usefulness of electron density imaging from dual-energy CT for detecting pulmonary thromboembolism in unenhanced CT. European radiology 2026. link 57 Taş A, Tanık VO, Tunca Ç, Ateş MS, Oğuz F, Kılıç C et al.. Albumin-Bilirubin and Platelet-Albumin-Bilirubin scores as predictors of all-cause long-term mortality in intermediate-high-risk pulmonary embolism. Irish journal of medical science 2026. link 58 Hill S, Webster E, Stewart D. Exploring Patterns of D-Dimer Assay Ordering at an Australian Rural Referral Hospital: A Retrospective Audit. Emergency medicine Australasia : EMA 2026. link 59 Song J, Chen R, Yu Y, Yang Y, Wang M, Wang D et al.. Predictive value of a combined clinical, serum biomarker, and radiomic model for poor short-term prognosis in acute pulmonary embolism. The international journal of cardiovascular imaging 2026. link 60 He R, Zhang X, Tang X, Shen Y, Liu H, Liu J et al.. The distinct etiology and imaging features of pediatric pulmonary embolism: dominance of Mycoplasma pneumoniae-associated in-situ thrombosis and severity risk stratification. Thrombosis research 2026. link 61 Vanni S, Pelagatti L, Caviglioli C, Fabiani G, Caldi F, Pellegrino A et al.. TELOS-plus identifies normotensive patients with pulmonary embolism at high risk of 30-day mortality. International journal of cardiology 2026. link 62 Lee ES, Baltsen CD, Stubblefield WB, Granfeldt A, Andersen A, Stannek K et al.. Intubation and Mechanical Ventilation in Patients with Acute Pulmonary Embolism: A Scoping Review. Journal of intensive care medicine 2026. link 63 Afifi AM, Fakih A, Leverich M, Ren G, Mouawad NJ, Nazzal M. National Trends, Gender, Racial, and Regional Disparities in Pulmonary Embolism Mortality Before and After the COVID-19 Pandemic in the United States: Analysis from the CDC-Wonder Database, 2018-2023. Annals of vascular surgery 2026. link 64 Li K, Nagpal P, Mullan BF, Wu Y, Garrett JW, Zhang R et al.. Image Quality Assessment of Deep Learning-Based Virtual Monoenergetic Images From Single-Energy CT Pulmonary Angiography. Journal of computer assisted tomography 2026. link 65 Jaramillo C, Ramirez-Garcia K, Ferguson EC, Restrepo CS, Ocazionez D. The PE puzzle: Identifying and differentiating mimics of acute and chronic pulmonary embolism on CTPA. Current problems in diagnostic radiology 2026. link 66 Hahn E, Snyder E, Dorey T, Abramowitz S, Jeyabalan G. Novel Use of the RevCore. Vascular and endovascular surgery 2026. link 67 Orozco-Zuñiga B, Cueto-Robledo G, Gonzalez-Hermosillo LM, Escobedo G, Navarro-Vergara DI, Garcia-Cesar M et al.. Saddle pulmonary embolism: results of a series of patients undergoing pharmaco-mechanical thrombolysis. Internal and emergency medicine 2026. link 68 Zghouzi M, Jabri A, Kumar S, Maligireddy A, Bista R, Paul TK et al.. Association between frailty, use of advanced therapies, in-hospital outcomes, and 30-day readmission in elderly patients admitted with acute pulmonary embolism. Cardiovascular revascularization medicine : including molecular interventions 2026. link 69 Stenger WJE, den Uil CA, Rietdijk WJR, Kraaijeveld AO, Klok FA. Effective risk stratification in pulmonary embolism: evaluating current tools and identifying research gaps. Heart (British Cardiac Society) 2026. link 70 Ramachandran A, Hammer MM, Madan R. The Many Faces of Nonthrombotic Pulmonary Artery Embolism. Radiographics : a review publication of the Radiological Society of North America, Inc 2026. link 71 Molina P, Morentin B, Hevia P, Monzó A, Lucena JS. Sudden death due to pulmonary embolism in young adults in Spain. Retrospective multicenter study of 128 forensic autopsy cases. Revista espanola de cardiologia (English ed.) 2026. link 72 Johnson F, Keller F, Fischer HT, Burian NM, Stenzl A, Borena W et al.. Impact of intermittent pneumatic compression stockings on pulmonary embolism rates after laryngectomy: A retrospective Before-After comparative study. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2026. link 73 Kim JM, Horbal SR, Mewaldt C, Ramachandran A, Yeh RW, Secemsky EA et al.. Mechanical Thrombectomy and Catheter-Directed Thrombolysis in Acute Pulmonary Embolism: Trends and Practice Patterns in the PERT Consortium Registry (2016-2024). Journal of the American College of Cardiology 2026. link 74 Nolan R, Samant M, Vedantham S, Ohman W, Droz N, Sanfilippo K et al.. Clinical Outcomes following Mechanical Thrombectomy in Pulmonary Embolism Response Team-Consulted Patients: A Retrospective Analysis. Journal of vascular and interventional radiology : JVIR 2026. link 75 Krasniqi LØ, Pietersen PI, Browne AGP, Gregersen S, Mussmann B. Dual-energy CT pulmonary angiography with reduced contrast media volume: Quantitative image quality compared with single-energy CT. Current problems in diagnostic radiology 2026. link 76 Schwartz FR, Khanungwanitkul K, Czajkowski B, Duraisamy S, Jhala K, Hammer MM et al.. Optimizing photon-counting CT pulmonary angiography for robustness, combining mixed bolus, fixed scan delay and low keV. European journal of radiology 2026. link 77 Gong M, Jiang R, He X, Gu J. Caval-Iliac Vein Angle and Risk of Pulmonary Embolism in Patients with Right-Sided Deep Vein Thrombosis. 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Clinical Characteristics, Risk Factors, and Outcomes of Cancer and Noncancer Patients with Hospital-Acquired Pulmonary Embolism: A Retrospective Cohort Study. Annals of vascular surgery 2026. link 85 Nijssen EC, Martens B, Hendriks BM, Gietema HA, Wildberger JE, Jeukens CRLPN. Computed tomography pulmonary angiography in around-the-clock clinical care with individualised scan protocols: a 5-year observational study on incidence and causes of repeat scanning. European radiology 2026. link 86 Liu J, Ni X, Zeng L, Song X, Diao S, Chen L et al.. Epidemiological characteristics of pulmonary thromboembolism in children: a systematic review and meta-analysis. BMJ open 2026. link 87 Zhang S, Li H, Chen Y, Xu X, Ji Y, Yang Y et al.. Leukocyte Count as an In-Hospital Prognostic Indicator in Acute Pulmonary Embolism: Evidence From a Registry Study and Genetic Analyses. Respirology (Carlton, Vic.) 2026. link 88 Akkan-Öz M, Mutlu H, Bulut B, Genç M, Yazici R, Gür A et al.. Platelet Indices and Cholinesterase in Diagnosis and Prognosis of Pulmonary Embolism. Clinical laboratory 2026. link 89 Smaniotto MF, Alencar E Silva GPS, Heringer JN, Almeida MTC, Scheffer MK, Felicioni SP et al.. Classical ECG findings in pulmonary embolism have minimal diagnostic accuracy: A cross-sectional study. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2026. link 90 Dunn A, Lee E, Harrison B, Scott S, McCaffrey J, Owen A. Multidisciplinary management of intermediate and high-risk pulmonary embolism in the era of mechanical thrombectomy: a local practice guideline. Internal medicine journal 2026. link 91 Ifergan A, Loutati R, Tvito A, Shuvy M, Carasso S, Deeb D et al.. Impact of time in therapeutic range (TTR) within the first 72 h on prognosis in patients with pulmonary embolism treated with unfractionated heparin. 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Fusing serum peptidome profiles with clinical variables via machine learning for pulmonary embolism risk assessment. Talanta 2026. link 96 Wessinger M, Gauchel N, Strobel D, Staudacher DL, Wengenmayer T, von Zur Mühlen C et al.. Characterizing technical success and clinical outcomes in patients with pulmonary embolism treated with ultrasound-assisted catheter-directed thrombolysis (USAT): a retrospective, single-center cohort study. Clinical research in cardiology : official journal of the German Cardiac Society 2026. link 97 Leupp S, Sarzilla S, Caruzzo CA, Landi A, Valgimigli M, Milzi A. Refining risk stratification in acute pulmonary embolism: A comparative validation of six prognostic scores in a real-life cohort. International journal of cardiology 2026. link 98 Yuriditsky E, Lyhne MD, Horowitz JM, Dudzinski DM. Critical Care Management of Acute Pulmonary Embolism. Journal of intensive care medicine 2026. link 99 Xiao R, Li X, Guo C, Suo S, Zheng K, Ma J et al.. CT Diagnostic Mode-Oriented and Cross Difficulty-Aware Network for Pulmonary Embolism Segmentation. IEEE transactions on medical imaging 2026. link 100 Elkholy M, Akkawi M, Kidess GG, Lin Z, Abdelrahman AK, Alsmairat Y et al.. Sex differences in in-hospital outcomes following catheter-based pulmonary embolism thrombectomy: Insights from a National Cohort. Heart & lung : the journal of critical care 2026. link

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