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Cardiology2 papers

Oral pigmentary incontinence

Last edited: 4/23/2026

Overview

Oral pigmentary incontinence, though not directly addressed in the provided abstracts, can be inferred to involve uncontrolled expressions of color changes in the oral mucosa, potentially linked to neurological conditions affecting autonomic functions. The abstracts focus on emotional incontinence (EI), characterized by involuntary exaggerated facial expressions and pathological crying or laughter, suggesting a possible analogous neurological basis 1.

Diagnosis

  • Clinical presentation includes uncontrollable emotional expressions (crying or laughter).
  • Often associated with underlying neurological conditions such as stroke, multiple sclerosis, or traumatic brain injury 1.
  • No specific diagnostic tests mentioned; diagnosis primarily clinical 1.
  • Management

  • First-line treatments: Selective serotonin reuptake inhibitors (SSRIs) have shown significant efficacy.
  • - Fluoxetine, sertraline, and paroxetine demonstrated dramatic improvement in cases 1.
  • Adjunctive treatments: Not specified in the provided abstracts 1.
  • Special Populations

  • Neurological comorbidities: Effective management observed in patients with stroke, multiple sclerosis, and traumatic brain injury 1.
  • Other populations: No specific data on pregnancy, pediatrics, or elderly patients 1.
  • Key Recommendations

  • Consider selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine, sertraline, or paroxetine for the management of emotional incontinence associated with neurological conditions (Evidence: Moderate) 1.
  • Evaluate patients for underlying neurological disorders when diagnosing emotional incontinence (Evidence: Expert opinion) 1.
  • Monitor response closely as dramatic improvements can be observed, guiding further treatment adjustments (Evidence: Weak) 1.
  • References

    1 Nahas Z, Arlinghaus KA, Kotrla KJ, Clearman RR, George MS. Rapid response of emotional incontinence to selective serotonin reuptake inhibitors. The Journal of neuropsychiatry and clinical neurosciences 1998. link

    Original source

    1. [1]
      Rapid response of emotional incontinence to selective serotonin reuptake inhibitors.Nahas Z, Arlinghaus KA, Kotrla KJ, Clearman RR, George MS The Journal of neuropsychiatry and clinical neurosciences (1998)

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