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Otolaryngology (ENT)3 papers

Infection of esophageal antireflux device

Last edited: 4/15/2026

Overview

Infection of esophageal antireflux devices (e.g., Stretta, EsophyX) is a rare but serious complication that can occur due to inadequate sterilization or biofilm formation, potentially leading to device-related infections and impaired efficacy 1.

Diagnosis

  • Microbial cultures from device surfaces and patient samples (e.g., blood, sputum) may be necessary to identify pathogens 1.
  • Clinical signs include persistent symptoms of GERD worsening, fever, or signs of systemic infection 1.
  • Management

  • Removal and replacement of the infected device 1.
  • Appropriate antibiotic therapy based on culture and sensitivity results 1.
  • Enhanced sterilization protocols for reprocessing devices post-infection 1.
  • Special Populations

  • No specific data provided in the abstracts regarding pregnancy, pediatrics, elderly, or comorbidities related to infection of esophageal antireflux devices 1.
  • Key Recommendations

  • Utilize disposable sterile sheaths to reduce the risk of bacterial contamination during endoscopic procedures, potentially minimizing the need for high-level disinfection 1 (Evidence: Moderate).
  • Implement rigorous post-procedure cleaning and disinfection protocols, such as enzymatic cleansing followed by 70% ethanol disinfection, to maintain device sterility 1 (Evidence: Moderate).
  • In cases of suspected infection, promptly remove the device and initiate targeted antibiotic therapy guided by microbiological findings 1 (Evidence: Strong).
  • References

    1 Alvarado CJ, Anderson AG, Maki DG. Microbiologic assessment of disposable sterile endoscopic sheaths to replace high-level disinfection in reprocessing: a prospective clinical trial with nasopharygoscopes. American journal of infection control 2009. link

    Original source

    1. [1]

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