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Infectious Disease4 papers

Genital Molluscum contagiosum

Last edited: 4/10/2026

Overview

Molluscum contagiosum is a viral skin infection caused by the Molluscipoxvirus. In adults, it commonly presents as a sexually transmitted infection affecting the genital area 1.

Diagnosis

  • Diagnosis is typically clinical, based on the characteristic appearance of dome-shaped, umbilicated papules 1.
  • No specific laboratory tests are routinely recommended for diagnosis 1.
  • Management

  • Treatment is indicated for symptomatic lesions, cosmetic concerns, or to prevent sexual transmission 1.
  • First-line treatments:
  • * Cryotherapy 1. * Potassium hydroxide (KOH) 1. * Curettage 1.
  • Adjunctive treatments:
  • * Topical cantharidin 1. * Topical imiquimod 1. * Topical tretinoin 1.

    Special Populations

  • No specific information on special populations (pregnancy, pediatrics, elderly, comorbidities) is provided in the abstracts.
  • Key Recommendations

  • Treatment should be considered for symptomatic lesions, cosmetic concerns, or to prevent sexual transmission 1. (Evidence: Expert opinion)
  • Clinical diagnosis is usually sufficient, and specific laboratory tests are not routinely required 1. (Evidence: Expert opinion)
  • A range of destructive therapies including cryotherapy, KOH, and curettage are considered first-line options 1. (Evidence: Expert opinion)
  • References

    1 Fernando I, K Edwards S, Grover D. British Association for Sexual Health and HIV national guideline for the management of Genital Molluscum in adults (2021). International journal of STD & AIDS 2022. link

    Original source

    1. [1]

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