HemoChat

Evidence-Based AI Medical Search

← Back to guidelines
Neurology8 papers

Micropapular yaws

Last edited: 4/10/2026

Overview

Micropapular yaws are a clinical variant of yaws, a chronic infectious disease caused by Treponema pallidum subspecies pertenue 1. This form is characterized by small, non-ulcerated papules, typically on the extremities 1.

Diagnosis

  • Diagnosis is primarily clinical, based on the characteristic appearance of lesions and epidemiological context 1.
  • Microscopic examination of lesion exudates for spirochetes may be performed 1.
  • Serological tests for syphilis (VDRL, RPR, TPHA) are usually reactive 1.

    • Management

  • First-line treatment is intramuscular benzathine penicillin G 1.
    • * Adults and children weighing >30 kg: 1.2 million units 1. * Children weighing ≤30 kg: 600,000 units 1.
  • Alternative treatments for penicillin-allergic individuals include oral azithromycin or doxycycline 1.
    • * Azithromycin: 500 mg once daily for 15 days 1. * Doxycycline: 100 mg twice daily for 15 days 1.

    Key Recommendations

  • Benzathine penicillin G is the recommended first-line treatment for yaws 1. (Evidence: Strong)
  • For penicillin-allergic individuals, azithromycin or doxycycline are recommended alternatives 1. (Evidence: Strong)
  • Diagnosis is primarily clinical, supported by serological tests and, if available, microscopic examination of lesions 1. (Evidence: Moderate)

    • References

    1 Cheeseman D. Practice question. Nursing older people 2015. link

    Original source

    1. [1]
      Practice question. — Cheeseman D Nursing older people (2015)
    Share:TwitterRedditLinkedIn

    HemoChat

    by SPINAI

    Evidence-based clinical decision support powered by SNOMED-CT, Neo4j GraphRAG, and NASS/AO/NICE guidelines.

    ⚕ For clinical reference only. Not a substitute for professional judgment.

    © 2026 HemoChat. All rights reserved.
    Research·Pricing·Privacy & Terms·Refund·SNOMED-CT · NASS · AO Spine · NICE · GraphRAG