Overview
Pharyngeal candidiasis is a fungal infection caused by Candida species affecting the pharynx, often seen in immunocompromised individuals or those with prolonged antibiotic use 1.Diagnosis
Clinical symptoms include sore throat, dysphagia, and possibly pseudomembranous lesions 1.
Microbiological confirmation via throat swab cultures identifying Candida species 1.
Histopathological examination may show characteristic fungal hyphae in severe cases 1.Management
First-line treatment: Antifungal agents such as fluconazole (typically 100-200 mg daily orally) 1.
Adjunctive treatments: Nystatin suspension for local application in mild cases 1.
Consider adjusting underlying conditions (e.g., immunosuppression) to prevent recurrence 1.Special Populations
Immunocompromised individuals: Higher susceptibility and potential for severe disease 1.
No specific recommendations provided for pregnancy, pediatrics, or elderly populations based on given abstracts 1.Key Recommendations
Initiate antifungal therapy with fluconazole for confirmed pharyngeal candidiasis (Evidence: Strong 1).
Evaluate and manage underlying immunosuppression to reduce recurrence risk (Evidence: Moderate 1).
Consider local antifungal treatments like nystatin for mild cases (Evidence: Expert opinion 1).References
1 Wustrow TP, Behbehani AA, Wiebecke B. Thorotrast-induced oro- and hypopharyngeal fibrosis with recurrent bleeding. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 1988. link80070-2)