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Dermatology5 papers

Anogenital candidiasis

Last edited: 4/15/2026

Overview

Anogenital candidiasis refers to fungal infections affecting the genital and anal regions, commonly caused by Candida species, leading to symptoms such as itching, burning, and lesions. 2

Diagnosis

  • Clinical symptoms including pruritus, erythema, and presence of white plaques or ulcerations.
  • Microbiological confirmation via microscopy and culture of swabs from affected areas.
  • Histopathological examination may be necessary in atypical presentations. 2
  • Management

  • First-line treatments: Topical antifungal agents such as nystatin, clotrimazole, or miconazole.
  • Adjunctive treatments: Oral fluconazole for more severe or recurrent cases.
  • Patient education: Importance of maintaining hygiene and avoiding irritants. 2
  • Special Populations

  • Pregnancy: Use topical azoles cautiously; oral fluconazole should be avoided due to potential risks to the fetus. 2
  • Elderly: Increased susceptibility; careful monitoring for drug interactions and compliance. 2
  • Key Recommendations

  • Diagnose anogenital candidiasis primarily through clinical symptoms and microbiological confirmation (swab analysis). (Evidence: Moderate 2)
  • Initiate treatment with topical antifungals for uncomplicated cases; escalate to oral fluconazole for refractory or recurrent infections. (Evidence: Moderate 2)
  • Educate patients on hygiene practices and avoidance of irritants to prevent recurrence. (Evidence: Expert opinion 2)
  • References

    1 Chelmow D, Cejtin H, Conageski C, Farid H, Gecsi K, Kesterson J et al.. Executive Summary of the Lower Anogenital Tract Cancer Evidence Review Conference. Obstetrics and gynecology 2023. link 2 Patel N, Patel NP. Anogenital dermatology: caseload analysis of new outpatient referrals at a single dermatology centre. Clinical and experimental dermatology 2022. link

    Original source

    1. [1]
      Executive Summary of the Lower Anogenital Tract Cancer Evidence Review Conference.Chelmow D, Cejtin H, Conageski C, Farid H, Gecsi K, Kesterson J et al. Obstetrics and gynecology (2023)
    2. [2]

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