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Gastroenterology2 papers

Cutaneous mucormycosis

Last edited: 4/15/2026

Overview

Cutaneous mucormycosis is a rare but serious fungal infection caused by fungi of the order Mucorales, typically affecting the skin and subcutaneous tissues, often following trauma or in immunocompromised individuals 1.

Diagnosis

  • Clinical Presentation: Localized swelling, pain, and erythema, often following trauma or exposure to contaminated environments 1.
  • Diagnostic Tests: Histological examination showing fungal hyphae and mycological culture identifying Mucorales 1.
  • Grading: No specific grading system mentioned in the abstract; diagnosis relies heavily on clinical context and laboratory confirmation 1.
  • Management

  • First-Line Treatment: Itraconazole and posaconazole (fruconazole likely refers to posaconazole) 1.
  • Duration: Treatment duration of at least five months observed in the case 1.
  • Monitoring: Regular clinical follow-up and reassessment of symptoms for gradual improvement 1.
  • Special Populations

  • Comorbidities: Patients with underlying conditions like alcoholic hepatopathy may be at higher risk 1.
  • Key Recommendations

  • Initiate antifungal therapy with itraconazole or posaconazole upon diagnosis of cutaneous mucormycosis (Evidence: Expert opinion 1).
  • Continue treatment for at least five months to ensure clinical improvement and prevent relapse (Evidence: Expert opinion 1).
  • Perform histological examination and mycological culture for definitive diagnosis (Evidence: Expert opinion 1).
  • References

    1 Mizutari K, Nishimoto K, Ono T. Cutaneous mucormycosis. The Journal of dermatology 1999. link

    Original source

    1. [1]
      Cutaneous mucormycosis.Mizutari K, Nishimoto K, Ono T The Journal of dermatology (1999)

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