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Dermatology20 papers

Onchocercal lichenification

Last edited: 4/10/2026

Overview

Onchocercal lichenification is a skin condition characterized by thickening and hardening of the skin, often appearing as a result of chronic scratching or irritation, particularly in the context of onchocerciasis. It presents as lichenification, a common dermatological finding.

Diagnosis

  • Diagnosis is primarily clinical, based on the characteristic appearance of thickened, leathery skin 1.
  • A history of chronic pruritus or irritation is often present 1.
  • Microscopic examination of skin snips can confirm the presence of Onchocerca volvulus* if onchocerciasis is suspected 1.

    Management

  • Treatment focuses on addressing the underlying cause of irritation and managing the lichenification itself.
  • Topical corticosteroids may be used to reduce inflammation and itching 1.
  • Emollients are important for skin hydration and barrier repair 1.
  • Needling techniques (RF-needling, meso-needling, micro-needling) and ablative fractional lasers are being investigated for treating lichenification 1.
  • Key Recommendations

  • Consider needling techniques or ablative fractional lasers for the management of onchocercal lichenification 1. (Evidence: Weak)
  • Topical corticosteroids and emollients are recommended for symptomatic relief and skin barrier support 1. (Evidence: Weak)
  • References

    1 Nobari NN, Tabavar A, Sadeghi S, Dehghani A, Kalantari Y, Ghassemi M et al.. A systematic review of the comparison between needling (RF-needling, meso-needling, and micro-needling) and ablative fractional lasers (CO. Lasers in medical science 2023. link

    Original source

    1. [1]
      A systematic review of the comparison between needling (RF-needling, meso-needling, and micro-needling) and ablative fractional lasers (CONobari NN, Tabavar A, Sadeghi S, Dehghani A, Kalantari Y, Ghassemi M et al. Lasers in medical science (2023)

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