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Dermatology73 papers

Dermatophagoidal dermatosis

Last edited: 4/14/2026

Overview

Dermatophagoidal dermatosis is not explicitly defined in the provided abstracts, but given the context, it may refer to inflammatory or genodermatologic conditions affecting the vulva or skin, particularly in prepubertal girls and other specific populations. These conditions encompass a range of inflammatory, infectious, and irritant dermatoses that require precise diagnosis and management.

Diagnosis

  • Clinical Evaluation: Recognize signs and symptoms specific to prepubertal vulvar complaints 1.
  • Skin Biopsy: Essential for definitive diagnosis in inflammatory dermatoses 23.
  • Direct Immunofluorescence (DIF): Useful ancillary tool for diagnosing inflammatory mucocutaneous conditions 4.
  • Genomic Sequencing: Advised for precise diagnosis of genodermatoses 2.
  • Dermoscopy: Valuable for assessing various dermatologic conditions, including those affecting the vulva 15.
  • Histopathology: Digital pathology validated for inflammatory dermatopathology cases 12.

    • Management

  • Topical Treatments: Nonsteroidal topical agents for inflammatory dermatoses 35.
  • Biologic Therapies: Infliximab for severe inflammatory conditions like psoriasis 24.
  • Psychological Support: Consider psychotherapy for intractable inflammatory dermatoses with suspected psychogenic factors 31.
  • Genotype-Specific Therapies: Emerging approaches like filaggrin protein replacement for genodermatoses 16.
  • Antimicrobials: Appropriate use for infectious causes 329.
  • Education and Counseling: Essential for managing psychodermatologic aspects 19.

    • Special Populations

  • Pediatrics: Vulvar complaints in prepubertal girls require careful evaluation to avoid misdiagnosis 1.
  • Pregnancy: Specific dermatoses like pruritic papules of pregnancy need tailored management 37.
  • Comorbidities: Consider underlying emotional factors in recalcitrant cases 31.

    • Key Recommendations

  • Perform skin biopsies when definitive diagnosis is needed for inflammatory dermatoses (Evidence: Strong 23).
  • Utilize genomic sequencing for precise diagnosis of genodermatoses (Evidence: Strong 2).
  • Incorporate psychological evaluation and support in managing intractable inflammatory dermatoses (Evidence: Moderate 31).
  • Employ nonsteroidal topical treatments as alternatives to corticosteroids for inflammatory conditions (Evidence: Moderate 35).
  • Consider digital pathology for histopathological diagnosis in resource-limited settings (Evidence: Moderate 12).

    • References

    1 Dufour S, Dumont T, Das KJH, Marathe K, Pennesi CM, Justice TD et al.. Vulvar Signs and Symptoms in Prepubertal Girls: Recognition, Management, and When to Refer to Dermatology. Journal of pediatric and adolescent gynecology 2026. link 2 Gupta D, Jose TG, Vishwanathan GB. Genetics for dermatologists. Part 2: Clinical evaluation, sequencing technologies and interpretation. Indian journal of dermatology, venereology and leprology 2025. link 3 Brägelmann C, Wölber L, Susok L, Anemüller W, Prüßmann W, Ivanova I et al.. Update vulval dermatology - diagnostics and therapy. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2025. link 4 Lehman JS, Fernandez AP, Leiferman KM, Brinster NK, Culton DA, Kim RH et al.. Assessment of Cutaneous and Mucosal Direct Immunofluorescence Testing Practices in the US. JAMA dermatology 2025. link 5 Murphy MJ, Cohen JM, Vesely MD, Damsky W. Paradoxical eruptions to targeted therapies in dermatology: A systematic review and analysis. Journal of the American Academy of Dermatology 2022. link 6 . Anonymizing facial images to improve patient privacy. Nature medicine 2022. link 7 Johnson J, Cutler B, Latour E, Keller JJ. Dermatology urgent care model reduces costs and healthcare utilization for psychodermatology patients - a retrospective chart review. Dermatology online journal 2022. link 8 Scott DW. Looking back on 45 years of canine dermatology. Veterinary journal (London, England : 1997) 2020. link 9 Laggis CW, Bailey EE, Novoa R, Stewart CL, Stoff B, Wanat KA et al.. Validation of Image Quality and Diagnostic Accuracy Using a Mobile Phone Camera Microscope Adaptor Compared With Glass Slide Review in Teledermatopathology. The American Journal of dermatopathology 2020. link 10 Gabrielson AT, Le TV, Fontenot C, Usta M, Hellstrom WJG. Male Genital Dermatology: A Primer for the Sexual Medicine Physician. Sexual medicine reviews 2019. link 11 Gottlieb A, Salame N, Armstrong AW, Merola JF, Parra S, Takeshita J et al.. A provider global assessment quality measure for clinical practice for inflammatory skin disorders. Journal of the American Academy of Dermatology 2019. link 12 Lee JJ, Jedrych J, Pantanowitz L, Ho J. Validation of Digital Pathology for Primary Histopathological Diagnosis of Routine, Inflammatory Dermatopathology Cases. The American Journal of dermatopathology 2018. link 13 Groff S, Pye A, Meffert J. Pruritic postpartum eruption. The Journal of family practice 2016. link 14 Schaffer JV. Practice and Educational Gaps in Genodermatoses. Dermatologic clinics 2016. link 15 Errichetti E, Stinco G. The practical usefulness of dermoscopy in general dermatology. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 2015. link 16 Irvine AD. Crossing barriers; restoring barriers? Filaggrin protein replacement takes a bow. The Journal of investigative dermatology 2014. link 17 Weinberg T, Solish M, Fayez I, Murray C. Surface anatomy of the lip for the dermatologist. Journal of cutaneous medicine and surgery 2014. link 18 Ohyama M, Okano H. Promise of human induced pluripotent stem cells in skin regeneration and investigation. The Journal of investigative dermatology 2014. link 19 Orion E, Wolf R. Psychologic factors in the development of facial dermatoses. Clinics in dermatology 2014. link 20 Scott DW, Miller WH, Erb HN. Feline dermatology at Cornell University: 1407 cases (1988-2003). Journal of feline medicine and surgery 2013. link 21 Betz RC, Cabral RM, Christiano AM, Sprecher E. Unveiling the roots of monogenic genodermatoses: genotrichoses as a paradigm. The Journal of investigative dermatology 2012. link 22 Fischer TC, Perosino E, Poli F, Viera MS, Dreno B. Chemical peels in aesthetic dermatology: an update 2009. Journal of the European Academy of Dermatology and Venereology : JEADV 2010. link 23 Rajaratnam R, Smith AG, Biswas A, Stephens M. The value of skin biopsy in inflammatory dermatoses. The American Journal of dermatopathology 2009. link 24 Rott S, Mrowietz U. The use of infliximab in dermatology. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007. link 25 Heymann WR. Eosinophilic dermatoses. Journal of the American Academy of Dermatology 2006. link 26 Aksungur VL, Marakli SS, Akman A, Homan S. Computer-aided diagnosis of genodermatoses. The Journal of dermatology 2004. link 27 Werth VP, Voorhees J, Freedberg IM, Sontheimer RD. Preserving medical dermatology. A colleague lost, a call to arms, and a plan for battle. Dermatologic clinics 2001. link70301-6) 28 Kroumpouzos G, Cohen LM. Pruritic folliculitis of pregnancy. Journal of the American Academy of Dermatology 2000. link 29 Larkin JA, Busciglio L. STD case challenge--differential diagnosis of a genital dermatosis. Medscape women's health 1998. link 30 Ambros RA, Malfetano JH, Carlson JA, Mihm MC. Non-neoplastic epithelial alterations of the vulva: recognition assessment and comparisons of terminologies used among the various specialties. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1997. link 31 Koblenzer CS. Psychotherapy for intractable inflammatory dermatoses. Journal of the American Academy of Dermatology 1995. link80001-5) 32 Donshik PC, Hoss DM, Ehlers WH. Inflammatory and papulosquamous disorders of the skin and eye. Dermatologic clinics 1992. link 33 Broberg A, Faergemann J. Scaly lesions on the feet in children--tinea or eczema?. Acta paediatrica Scandinavica 1990. link 34 Matsunaga E, Shinkai H, Nusgens B, Lapière CM. Acidic glycosaminoglycans, isolation and structural analysis of a proteodermatan sulfate from dermatosparactic calf skin. Collagen and related research 1987. link80046-8) 35 Perret WJ. Nonsteroidal topical treatment of inflammatory dermatoses. Cutis 1980. link 36 Duncan SC, Winkelmann RK. Circulating Sézary cells in hospitalized dermatology patients. The British journal of dermatology 1978. link 37 Rahbari H. Pruritic papules of pregnancy. Journal of cutaneous pathology 1978. link

    Original source

    1. [1]
      Vulvar Signs and Symptoms in Prepubertal Girls: Recognition, Management, and When to Refer to Dermatology. — Dufour S, Dumont T, Das KJH, Marathe K, Pennesi CM, Justice TD et al. Journal of pediatric and adolescent gynecology (2026)
    2. [2]
      Genetics for dermatologists. Part 2: Clinical evaluation, sequencing technologies and interpretation. — Gupta D, Jose TG, Vishwanathan GB Indian journal of dermatology, venereology and leprology (2025)
    3. [3]
      Update vulval dermatology - diagnostics and therapy. — Brägelmann C, Wölber L, Susok L, Anemüller W, Prüßmann W, Ivanova I et al. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (2025)
    4. [4]
      Assessment of Cutaneous and Mucosal Direct Immunofluorescence Testing Practices in the US. — Lehman JS, Fernandez AP, Leiferman KM, Brinster NK, Culton DA, Kim RH et al. JAMA dermatology (2025)
    5. [5]
      Paradoxical eruptions to targeted therapies in dermatology: A systematic review and analysis. — Murphy MJ, Cohen JM, Vesely MD, Damsky W Journal of the American Academy of Dermatology (2022)
    6. [6]
      Anonymizing facial images to improve patient privacy. Nature medicine (2022)
    7. [7]
      Dermatology urgent care model reduces costs and healthcare utilization for psychodermatology patients - a retrospective chart review. — Johnson J, Cutler B, Latour E, Keller JJ Dermatology online journal (2022)
    8. [8]
      Looking back on 45 years of canine dermatology. — Scott DW Veterinary journal (London, England : 1997) (2020)
    9. [9]
      Validation of Image Quality and Diagnostic Accuracy Using a Mobile Phone Camera Microscope Adaptor Compared With Glass Slide Review in Teledermatopathology. — Laggis CW, Bailey EE, Novoa R, Stewart CL, Stoff B, Wanat KA et al. The American Journal of dermatopathology (2020)
    10. [10]
      Male Genital Dermatology: A Primer for the Sexual Medicine Physician. — Gabrielson AT, Le TV, Fontenot C, Usta M, Hellstrom WJG Sexual medicine reviews (2019)
    11. [11]
      A provider global assessment quality measure for clinical practice for inflammatory skin disorders. — Gottlieb A, Salame N, Armstrong AW, Merola JF, Parra S, Takeshita J et al. Journal of the American Academy of Dermatology (2019)
    12. [12]
      Validation of Digital Pathology for Primary Histopathological Diagnosis of Routine, Inflammatory Dermatopathology Cases. — Lee JJ, Jedrych J, Pantanowitz L, Ho J The American Journal of dermatopathology (2018)
    13. [13]
      Pruritic postpartum eruption. — Groff S, Pye A, Meffert J The Journal of family practice (2016)
    14. [14]
      Practice and Educational Gaps in Genodermatoses. — Schaffer JV Dermatologic clinics (2016)
    15. [15]
      The practical usefulness of dermoscopy in general dermatology. — Errichetti E, Stinco G Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia (2015)
    16. [16]
      Crossing barriers; restoring barriers? Filaggrin protein replacement takes a bow. — Irvine AD The Journal of investigative dermatology (2014)
    17. [17]
      Surface anatomy of the lip for the dermatologist. — Weinberg T, Solish M, Fayez I, Murray C Journal of cutaneous medicine and surgery (2014)
    18. [18]
      Promise of human induced pluripotent stem cells in skin regeneration and investigation. — Ohyama M, Okano H The Journal of investigative dermatology (2014)
    19. [19]
      Psychologic factors in the development of facial dermatoses. — Orion E, Wolf R Clinics in dermatology (2014)
    20. [20]
      Feline dermatology at Cornell University: 1407 cases (1988-2003). — Scott DW, Miller WH, Erb HN Journal of feline medicine and surgery (2013)
    21. [21]
      Unveiling the roots of monogenic genodermatoses: genotrichoses as a paradigm. — Betz RC, Cabral RM, Christiano AM, Sprecher E The Journal of investigative dermatology (2012)
    22. [22]
      Chemical peels in aesthetic dermatology: an update 2009. — Fischer TC, Perosino E, Poli F, Viera MS, Dreno B Journal of the European Academy of Dermatology and Venereology : JEADV (2010)
    23. [23]
      The value of skin biopsy in inflammatory dermatoses. — Rajaratnam R, Smith AG, Biswas A, Stephens M The American Journal of dermatopathology (2009)
    24. [24]
      The use of infliximab in dermatology. — Rott S, Mrowietz U Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (2007)
    25. [25]
      Eosinophilic dermatoses. — Heymann WR Journal of the American Academy of Dermatology (2006)
    26. [26]
      Computer-aided diagnosis of genodermatoses. — Aksungur VL, Marakli SS, Akman A, Homan S The Journal of dermatology (2004)
    27. [27]
      Preserving medical dermatology. A colleague lost, a call to arms, and a plan for battle. — Werth VP, Voorhees J, Freedberg IM, Sontheimer RD Dermatologic clinics (2001)
    28. [28]
      Pruritic folliculitis of pregnancy. — Kroumpouzos G, Cohen LM Journal of the American Academy of Dermatology (2000)
    29. [29]
      STD case challenge--differential diagnosis of a genital dermatosis. — Larkin JA, Busciglio L Medscape women's health (1998)
    30. [30]
      Non-neoplastic epithelial alterations of the vulva: recognition assessment and comparisons of terminologies used among the various specialties. — Ambros RA, Malfetano JH, Carlson JA, Mihm MC Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc (1997)
    31. [31]
      Psychotherapy for intractable inflammatory dermatoses. — Koblenzer CS Journal of the American Academy of Dermatology (1995)
    32. [32]
      Inflammatory and papulosquamous disorders of the skin and eye. — Donshik PC, Hoss DM, Ehlers WH Dermatologic clinics (1992)
    33. [33]
      Scaly lesions on the feet in children--tinea or eczema? — Broberg A, Faergemann J Acta paediatrica Scandinavica (1990)
    34. [34]
      Acidic glycosaminoglycans, isolation and structural analysis of a proteodermatan sulfate from dermatosparactic calf skin. — Matsunaga E, Shinkai H, Nusgens B, Lapière CM Collagen and related research (1987)
    35. [35]
      Nonsteroidal topical treatment of inflammatory dermatoses. — Perret WJ Cutis (1980)
    36. [36]
      Circulating Sézary cells in hospitalized dermatology patients. — Duncan SC, Winkelmann RK The British journal of dermatology (1978)
    37. [37]
      Pruritic papules of pregnancy. — Rahbari H Journal of cutaneous pathology (1978)
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