Overview
Influenza B virus is a cause of seasonal influenza, a contagious respiratory illness. It is one of the two main types of influenza viruses that cause seasonal epidemics in humans, the other being influenza A virus.Diagnosis
Diagnosis is typically based on clinical symptoms, but laboratory confirmation can be performed.
Specific diagnostic tests are not detailed in the provided abstracts.Management
Baloxavir marboxil (BXM) and oseltamivir are antiviral medications used for influenza treatment 1.
In inpatients, BXM significantly shortened hospitalization period compared to oseltamivir 1.
In outpatients, BXM had a significantly lower incidence of adverse events, reductions in influenza virus titers, and viral RNA loads, with a tendency towards shorter illness duration compared to oseltamivir 1.
Further details on specific drug classes, doses, or adjunctive treatments are not provided.Special Populations
The abstracts mention studies involving outpatients and inpatients, but do not specifically detail management in pregnant individuals, pediatric patients, the elderly, or those with comorbidities.Key Recommendations
Baloxavir marboxil may be considered for the treatment of influenza, showing potential benefits in reducing hospitalization duration in inpatients and adverse events in outpatients compared to oseltamivir 1. (Evidence: Strong)
Oseltamivir is an established treatment for influenza 1. (Evidence: Strong)References
1 Shiraishi C, Kato H, Hagihara M, Asai N, Iwamoto T, Mikamo H. Comparison of clinical efficacy and safety of baloxavir marboxil versus oseltamivir as the treatment for influenza virus infections: A systematic review and meta-analysis. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2024. link