Overview
Laryngeal scar refers to tissue damage and subsequent fibrosis in the larynx, often resulting from trauma, surgery, or chronic inflammation, leading to functional and aesthetic impairments 1.Diagnosis
Clinical assessment using grading scales (e.g., Quartile Grading Scale) 1
Histopathological evaluation with stains like H&E, trichrome, and Orcein for detailed assessment 1Management
Microneedling combined with Platelet-Rich Plasma (PRP): Four sessions shown to significantly improve atrophic post-traumatic scars clinically and histopathologically 1
Fractional Er:YAG Laser: Four sessions at 4-week intervals also effective for scar improvement 1
No significant difference noted between varying session numbers of microneedling with PRP (4 vs. 6 sessions) 1Special Populations
Pregnancy: Not directly addressed in provided abstracts 2
Caesarean Scar Pregnancy: Specific to uterine scarring; management via hysteroscopic removal reported for ectopic pregnancies, not laryngeal scarring 2Key Recommendations
Consider microneedling combined with PRP as a first-line treatment for laryngeal atrophic scars, with four sessions, for significant clinical and histopathological improvement (Evidence: Moderate 1)
Fractional Er:YAG laser can serve as an adjunctive treatment option, administered in four sessions at 4-week intervals (Evidence: Moderate 1)
Histopathological evaluation using specialized stains should accompany clinical grading for comprehensive assessment of treatment efficacy (Evidence: Moderate 1)References
1 Agamia NF, Sorror O, Alrashidy M, Tawfik AA, Badawi A. Clinical and histopathological comparison of microneedling combined with platelets rich plasma versus fractional erbium-doped yttrium aluminum garnet (Er: YAG) laser 2940 nm in treatment of atrophic post traumatic scar: a randomized controlled study. The Journal of dermatological treatment 2021. link
2 Mollo A, Alviggi C, Conforti A, Insabato L, De Placido G. Intact removal of spontaneous twin ectopic Caesarean scar pregnancy by office hysteroscopy: case report and literature review. Reproductive biomedicine online 2014. link