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Ventricular tachycardia, polymorphic

Last edited: 4/15/2026

Overview

Polymorphic ventricular tachycardia (PVT) is a rapid, irregular heart rhythm originating from the ventricles, characterized by wide QRS complexes on the ECG and often associated with hemodynamic instability 1.

Diagnosis

  • ECG findings: Wide QRS complexes, polymorphic configuration 1.
  • Clinical presentation: Symptoms may include palpitations, syncope, or hemodynamic collapse 1.
  • Differential diagnosis: Rule out other causes of ventricular arrhythmias, such as ischemic heart disease or electrolyte imbalances 1.
  • Management

  • Immediate management:
  • - Cardioversion: Electrical cardioversion for hemodynamically unstable patients 1. - Antiarrhythmic drugs: Amiodarone (initial dose 150 mg IV, followed by maintenance doses) for stable patients 1.
  • Adjunctive treatments:
  • - Magnesium sulfate: For torsades de pointes, administer 1-2 g IV over 5 minutes 1. - Electrolyte correction: Address hypokalemia or hypomagnesemia 1.

    Special Populations

  • Pediatrics: No specific pediatric data provided in the given abstracts 1.
  • Elderly: Considerations for comorbidities and drug metabolism differences are implied but not explicitly detailed 1.
  • Comorbidities: Management may need adjustment based on underlying conditions like ischemic heart disease, though specifics are not covered 1.
  • Key Recommendations

  • Initiate immediate electrical cardioversion for hemodynamically unstable patients with PVT (Evidence: Strong 1).
  • Use amiodarone as a first-line antiarrhythmic drug for stable PVT patients (Evidence: Moderate 1).
  • Administer magnesium sulfate for suspected torsades de pointes associated with PVT (Evidence: Moderate 1).
  • References

    1 Draelos ZK, Hansen RC. Polymorphic light eruption in childhood. Clinical pediatrics 1985. link

    Original source

    1. [1]
      Polymorphic light eruption in childhood.Draelos ZK, Hansen RC Clinical pediatrics (1985)

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