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Neurology3 papers

Laminar heterotopia

Last edited: 4/10/2026

Overview

Laminar heterotopia is a rare neuronal migration disorder characterized by misplaced grey matter within the white matter of the brain 1. It can present with varied symptoms depending on age, including seizures or behavioral issues 1. In rare instances, it can mimic acute stroke 1.

Diagnosis

  • Consider grey matter heterotopia in patients presenting with stroke-like symptoms 1.
  • Management

  • No management strategies are described in the provided abstracts.
  • Special Populations

  • Presentation can vary with age 1.
  • Key Recommendations

  • Consider grey matter heterotopia as a differential diagnosis in patients presenting with stroke-like symptoms 1. (Evidence: Weak)
  • References

    1 Yasir Rafiq M, Fasey L, Abdullah M, Salam A. Grey matter heterotopia mimicking acute stroke. The journal of the Royal College of Physicians of Edinburgh 2022. link

    Original source

    1. [1]
      Grey matter heterotopia mimicking acute stroke.Yasir Rafiq M, Fasey L, Abdullah M, Salam A The journal of the Royal College of Physicians of Edinburgh (2022)

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