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Cardiology16 papers

Left atrial appendage absent

Last edited: 4/22/2026

Overview

Left atrial appendage (LAA) absence is a rare congenital anomaly characterized by the absence of the LAA, which can complicate the assessment and management of atrial thrombi and surgical interventions.

Diagnosis

  • Diagnostic Imaging: Real-time 3-dimensional transesophageal echocardiography (RT3DTEE) offers higher specificity compared to 2-dimensional TEE for assessing LAA thrombosis 1.
  • Challenges: Differentiation between thrombus, trabeculae, and artifacts in LAA can be difficult with 2D TEE 1.
  • Unusual Anomalies: Congenital defects involving the pericardium may lead to unique complications such as strangulation of the LAA 2.
  • Management

  • Surgical Intervention: Appendectomy and closure of congenital pericardial defects may be required in cases of strangulation 2.
  • Further Imaging: RT3DTEE can refine or change the diagnosis in cases where initial 2D TEE findings are uncertain 1.
  • Special Populations

  • Congenital Anomalies: Specific surgical considerations are necessary in patients with congenital defects affecting the LAA and pericardium 2.
  • Key Recommendations

  • Utilize real-time 3-dimensional transesophageal echocardiography for improved diagnostic accuracy in assessing left atrial appendage conditions (Evidence: Moderate) 1.
  • Consider surgical intervention, including appendectomy and defect closure, in cases of LAA strangulation due to congenital anomalies (Evidence: Weak) 2.
  • Refine diagnostic approaches with advanced imaging techniques when initial findings are inconclusive to avoid misdiagnosis (Evidence: Expert opinion) 1.
  • References

    1 Marek D, Vindis D, Kocianova E. Real time 3-dimensional transesophageal echocardiography is more specific than 2-dimensional TEE in the assessment of left atrial appendage thrombosis. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 2013. link 2 Robin E, Ganguly SN, Fowler MS. Strangulation of the left atrial appendage through a congenital partial pericardial defect. Chest 1975. link

    Original source

    1. [1]
      Real time 3-dimensional transesophageal echocardiography is more specific than 2-dimensional TEE in the assessment of left atrial appendage thrombosis.Marek D, Vindis D, Kocianova E Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia (2013)
    2. [2]

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