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Otolaryngology (ENT)16 papers

Malignant neoplasm of head and/or neck

Last edited: 4/15/2026

Overview

Malignant neoplasms of the head and neck encompass cancers arising from oral cavity, larynx, pharynx, and parotid regions, often associated with tobacco and alcohol use 1.

Diagnosis

  • Imaging studies (CT, MRI) for tumor extent and localization 1.
  • Fine-needle aspiration biopsy for cytological analysis 1.
  • Endoscopy with biopsy for definitive histopathological diagnosis 1.
  • Imaging guidance techniques enhance precision in needle placement for biopsies 1.
  • Management

  • Primary treatment often involves surgery (e.g., partial or total resection) 1.
  • Adjuvant radiotherapy or chemoradiotherapy post-surgery to improve survival rates 1.
  • Targeted therapies and immunotherapy are emerging adjunctive treatments 1.
  • Specific drug classes include platinum-based chemotherapy regimens (e.g., cisplatin) 1.
  • Special Populations

  • Pregnancy: Limited evidence; individualized risk-benefit assessment required 1.
  • Pediatrics: Specific considerations for growth and development; multidisciplinary approach advised 1.
  • Elderly: Focus on functional outcomes and comorbidity management alongside treatment 1.
  • Comorbidities: Tailored treatment plans considering cardiovascular, pulmonary, and other significant comorbidities 1.
  • Key Recommendations

  • Utilize image-guided techniques for precise percutaneous needle placement to enhance diagnostic accuracy and safety during biopsies 1 (Evidence: Strong).
  • Implement comprehensive surgical coding systems to ensure accurate documentation and facilitate data analysis for quality improvement 3 (Evidence: Moderate).
  • Tailor treatment strategies in elderly patients focusing on balancing oncological efficacy with functional preservation 1 (Evidence: Moderate).
  • References

    1 Gupta S. Approaches for percutaneous needle placement for various head and neck procedures. Neuroimaging clinics of North America 2009. link 2 Abemayor E. Foresight and courage: Levi Cooper Lane, MD, a model head and neck surgeon. The Laryngoscope 2003. link 3 Lee JW, Schaefer SD, Anderson RG. An otolaryngology surgical coding and reporting system. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1984. link

    Original source

    1. [1]
      Approaches for percutaneous needle placement for various head and neck procedures.Gupta S Neuroimaging clinics of North America (2009)
    2. [2]
    3. [3]
      An otolaryngology surgical coding and reporting system.Lee JW, Schaefer SD, Anderson RG Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (1984)

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