Epidemiology
Among nonsmokers, prescription of NSAIDs was associated with a 43% reduction in bladder cancer risk (OR = 0.57, 95% CI = 0.33, 0.98) [PMID:14969797].
Management
The study suggests a potential protective role of NSAIDs in nonsmokers, warranting further investigation into their use for bladder cancer prevention [PMID:14969797].
Key Recommendations
Given the observed reduction in risk among nonsmokers using NSAIDs, there is a need for additional studies to confirm these findings and guide clinical recommendations [PMID:14969797]. (Evidence: Moderate)
References
1 Blumentals WA, Foulis PR, Schwartz SW, Mason TJ. Analgesic therapy and the prevention of bladder cancer. Urologic oncology 2004. link00100-5)
1 papers cited of 3 indexed.