Overview
Anovulatory infertility is a common cause of female infertility characterized by the absence of ovulation 1. Luteinizing hormone (LH) plays a crucial role in regulating the menstrual cycle and is involved in ovarian stimulation for ovulation induction and assisted reproduction 1.Diagnosis
Diagnosis is based on clinical presentation and hormonal evaluation to confirm the absence of ovulation.
LH activity is a key regulator of ovarian folliculogenesis and is considered in the management of anovulatory infertility 1.Management
LH activity is contained in medications used to treat anovulation and stimulate folliculogenesis 1.
Pharmacological amounts of LH activity may be therapeutically advantageous in supporting and modulating ovarian folliculogenesis 1.
Novel gonadotropin regimens incorporating LH activity may improve the efficacy, safety, and convenience of ovulation induction 1.Key Recommendations
LH activity is therapeutically advantageous in the support and modulation of ovarian folliculogenesis 1. (Evidence: Moderate)
Novel gonadotropin regimens that include LH activity may improve the efficacy, safety, and convenience of ovulation induction 1. (Evidence: Moderate)
LH activity is a crucial physiological regulator of the human menstrual cycle and is utilized in medications for anovulation treatment 1. (Evidence: Moderate)References
1 Filicori M, Cognigni GE, Pocognoli P, Ciampaglia W, Bernardi S. Current concepts and novel applications of LH activity in ovarian stimulation. Trends in endocrinology and metabolism: TEM 2003. link00085-7)