← Back to guidelines
Hematology2227 papers

Anemia

Last edited: 4/23/2026

Overview

Anemia is a condition characterized by a deficiency in red blood cells or hemoglobin, leading to impaired oxygen delivery to tissues. It affects diverse populations globally, with significant impacts on maternal health, pediatric development, and surgical outcomes.

Diagnosis

  • Complete Blood Count (CBC): Essential for measuring hemoglobin levels, hematocrit, and red blood cell indices 219.
  • Reticulocyte Count: Evaluates bone marrow response to anemia 24.
  • Iron Studies: Serum iron, ferritin, total iron-binding capacity (TIBC), and transferrin saturation to differentiate iron deficiency anemia 15.
  • Vitamin B12 and Folate Levels: To rule out deficiencies in these nutrients 21228.
  • Hemoglobin Variants and Hemolysis Workup: Including osmotic fragility test and haptoglobin levels 77.
  • Management

  • Iron Supplementation: Oral iron for iron deficiency anemia; dose typically 100-200 mg elemental iron daily 1528.
  • Intravenous Iron: For severe anemia or intolerance to oral iron; guided by clinical response and ferritin levels 1832.
  • Erythropoiesis-Stimulating Agents (ESAs): In chronic kidney disease or cancer-related anemia 22.
  • Blood Transfusion: For symptomatic severe anemia or perioperative management 2258.
  • Vitamin D Supplementation: For anemia of inflammation, aiming to reduce hepcidin levels 12.
  • Folic Acid and Vitamin B12: Supplementation for deficiencies contributing to anemia 228.
  • Special Populations

  • Pregnancy: Maintain hemoglobin levels above 11 g/dL; iron and folic acid supplementation recommended 71659.
  • Pediatrics: Iron supplementation and nutritional interventions crucial; monitor growth and development 1666.
  • Elderly: Consider underlying chronic diseases; assess for multiple deficiencies including iron, vitamin B12, and folate 2530.
  • Comorbidities: Tailor management based on coexisting conditions like chronic kidney disease or cancer 2232.
  • Key Recommendations

  • Maintain Hemoglobin Levels in Pregnancy: Aim for hemoglobin levels above 11 g/dL with appropriate supplementation (iron, folic acid) to reduce maternal and neonatal risks 71659 (Evidence: Strong).
  • Use Intravenous Iron for Severe Anemia: Consider IV iron therapy in patients with severe anemia or those unresponsive to oral iron 1832 (Evidence: Moderate).
  • Screen for Micronutrient Deficiencies: Regularly assess vitamin B12, folate, and iron levels in elderly patients to manage anemia effectively 2530 (Evidence: Moderate).
  • Monitor and Manage Preoperative Anemia: Optimize hemoglobin levels before surgery to reduce perioperative complications 15 (Evidence: Moderate).
  • Consider Vitamin D Supplementation in Anemia of Inflammation: Reduce hepcidin levels to improve iron utilization 12 (Evidence: Moderate).
  • References

    Showing 100 most recent of 420 indexed papers.

    1 Maynard S, Farrington J, Raza S, Stanworth SJ. Artificial Intelligence Implementation in Transfusion Medicine: Addressing the Challenges of Clinical Adoption. Transfusion medicine reviews 2026. link 2 Shean RC, Bennett ST. Clinical Evaluation of a Novel Point-of-Care Hematology Analyzer for Complete Blood Count With Differential. International journal of laboratory hematology 2026. link 3 Güntner AT, Gerber PA, Dittrich PS, Serra N, Figalli A, Puhan MA et al.. Challenges and opportunities of wearable molecular sensors in endocrinology and metabolism. Nature reviews. Endocrinology 2026. link 4 Maberry MD, Smith CJ, Go RS. Clinical Utility of Monoclonal Gammopathy Testing in the Evaluation of Anemia. American journal of hematology 2026. link 5 Yang CC, Lin CS, Lin C, Liu WT, Lai ZY, Chuang YJ. Non-invasive hemoglobin estimation with outcome prediction via deep learning analysis of ECG-derived cardiac micro-dynamics. Internal and emergency medicine 2026. link 6 Manley J, Alderman H. Do Cash Transfer Programmes Affect Child Anaemia? Results From a Meta-Analysis. Maternal & child nutrition 2025. link 7 Ubom AE, Begum F, Ramasauskaite D, Nieto-Calvache AJ, Oguttu M, Nunes I et al.. FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH). International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2025. link 8 Lv X, Wang D, Zou X. Systematic review and meta-analysis of Guipi Decoction in the treatment of anemia. Medicine 2025. link 9 Catovic-Baralija E. Assessment of Recipient Characteristics and Blood Product Usage Patterns at the Transfusion Medicine Institute of FBiH in 2023. Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina 2025. link 10 Jang Y, Eom YJ, Gwak SH, Koh Y, Han J, Rim YA et al.. Advances in the characterization of in vitro-generated red blood cells: from biophysical properties to functional applications. Stem cell research & therapy 2025. link 11 Mao B, Chen Y, Wang C, Ma Y, Gu H, Shen Y et al.. Haemoglobin for Fall Risk Screening in Gynaecological and Obstetric Wards: Retrospective Survey and Delphi Validation. Nursing open 2025. link 12 Xu P, Liu G, Chen B. Vitamin D supplementation ameliorates anemia of inflammation by reducing hepcidin levels and inactivating inflammatory signaling pathways. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 2025. link 13 Wu D, Xie T, Jiao S, Xie P, Lin H, Yu G. Cardiovascular toxicities of hypoxia-inducible factor prolyl hydroxylase inhibitors: a disproportionality analysis based on JADER database. Expert opinion on drug safety 2025. link 14 Li H, Hu Q, Zhu D, Wu D. The Role of NAD. American journal of cardiovascular drugs : drugs, devices, and other interventions 2025. link 15 Hands K, Daru J, Evans C, Kotze A, Lewis C, Narayan S et al.. Identification and management of preoperative anaemia in adults: A British Society for Haematology Guideline update. British journal of haematology 2024. link 16 Zhou Y, Lyu Y, Ye W, Shi H, Peng Y, Wen Z et al.. The Prevalence of Anemia among Pregnant Women in China: A Systematic Review and Meta-Analysis. Nutrients 2024. link 17 Zhao B, Sun M, Wu T, Li J, Shi H, Wei Y. The association between maternal anemia and neonatal anemia: a systematic review and meta-analysis. BMC pregnancy and childbirth 2024. link 18 Meyers M, Salmon M, Libert I, Klášterský J. A meta-analysis on the risk of infection associated with intravenous iron therapy in cancer-associated anaemia: a double-edged sword?. Current opinion in oncology 2024. link 19 Shean RC, Williams MC, Rets AV. Advances in Hematology Analyzers Technology. Clinics in laboratory medicine 2024. link 20 Wautier JL. Molecular Research of Regulation of Red Blood Cells in Health, Hereditary or Acquired Diseases. International journal of molecular sciences 2024. link 21 George A, Shastry S, Mohan G, Belurkar S. Evaluating patient blood management practices using PBM metrics in a tertiary care center. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 2024. link 22 Kalra SK, Auron M. Anemia and Transfusion Medicine. The Medical clinics of North America 2024. link 23 Yazdanbakhsh M, Acker JP. Advancing in vivo assessment of red blood cell transfusions: A call for radiation-free methods in transfusion medicine. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2024. link 24 Obstfeld AE, Davis BH, Han JY, Urrechaga E. Report of the International Council for Standardization in Haematology working group for standardization of reticulocyte parameters. International journal of laboratory hematology 2024. link 25 Soraci L, de Vincentis A, Aucella F, Fabbietti P, Corsonello A, Arena E et al.. Prevalence, risk factors, and treatment of anemia in hospitalized older patients across geriatric and nephrological settings in Italy. Scientific reports 2024. link 26 Tessema NS, Geda NR. Child health outcomes and associated factors among under five years children in Ethiopia: a population attributable fractions analysis of Ethiopia demographic and health survey (2005-2016). BMC pediatrics 2024. link 27 Basrowi RW, Zulfiqqar A, Sitorus NL. Anemia in Breastfeeding Women and Its Impact on Offspring's Health in Indonesia: A Narrative Review. Nutrients 2024. link 28 Liu L, Zhou J, Chen C, Qu Y, Wang J, Lu F et al.. Vitamin B. BMC geriatrics 2024. link 29 Ahamed F, Jaiswal A, Sahoo S, Ghosh T, Kaur A, Rehman T et al.. Impact of supplementation with iron-folic acid (IFA) and vitamin D. BMJ open 2024. link 30 Qasrawi R, Badrasawi M, Al-Halawa DA, Polo SV, Khader RA, Al-Taweel H et al.. Identification and prediction of association patterns between nutrient intake and anemia using machine learning techniques: results from a cross-sectional study with university female students from Palestine. European journal of nutrition 2024. link 31 Shima A, Kawatsu Y, Morino A, Okawara M, Hirashima K, Miyamatsu N et al.. Relationship between anemia and occupational fall injuries in female part-time employees: an observational study of large supermarket stores in Japan. Journal of occupational health 2024. link 32 Zhang S, Ouyang M, Liu L. The treatment effects and cardiovascular events of high-dose intravenous iron for hemodialysis patients with renal anemia: A systematic review and meta-analysis. Chronic illness 2024. link 33 Lim J, Auerbach M, MacLean B, Al-Sharea A, Richards T. Intravenous Iron Therapy to Treat Anemia in Oncology: A Mapping Review of Randomized Controlled Trials. Current oncology (Toronto, Ont.) 2023. link 34 Andersen CT, Marsden DM, Duggan CP, Liu E, Mozaffarian D, Fawzi WW. Oral iron supplementation and anaemia in children according to schedule, duration, dose and cosupplementation: a systematic review and meta-analysis of 129 randomised trials. BMJ global health 2023. link 35 Young MF, Oaks BM, Rogers HP, Tandon S, Martorell R, Dewey KG et al.. Maternal low and high hemoglobin concentrations and associations with adverse maternal and infant health outcomes: an updated global systematic review and meta-analysis. BMC pregnancy and childbirth 2023. link 36 Kundu S, Alam SS, Mia MA, Hossan T, Hider P, Khalil MI et al.. Prevalence of Anemia among Children and Adolescents of Bangladesh: A Systematic Review and Meta-Analysis. International journal of environmental research and public health 2023. link 37 Ciont C, Mesaroș A, Pop OL, Vodnar DC. Iron oxide nanoparticles carried by probiotics for iron absorption: a systematic review. Journal of nanobiotechnology 2023. link 38 McNally SA. Perioperative management of patients with anaemia: a new guideline. British journal of hospital medicine (London, England : 2005) 2023. link 39 Prieto García B, González Santiago JM, Gómez-Caminero López F. Splenosis as an incidental finding in a patient with multifactorial anemia. Revista espanola de enfermedades digestivas 2023. link 40 Park JY, Grant CC. Prevalence of anaemia in acutely unwell infants. The New Zealand medical journal 2023. link 41 Ufelle Silas Anayo -, Onyekwelu Kenechukwu -, Chikwendu Chiedozie Kenechi -. Analysis of haematological effects of Picralima nitida. Pakistan journal of pharmaceutical sciences 2023. link 42 D'Alessandro A, Hod EA. Red Blood Cell Storage: From Genome to Exposome Towards Personalized Transfusion Medicine. Transfusion medicine reviews 2023. link 43 Roberts DJ, Dhabangi A. Debate: Should the loss of disability adjusted life years (DALY) define the focus of Global Hematology?: The case for prioritizing capacity building in anemia management and blood transfusion. Seminars in hematology 2023. link 44 Alarcón-Yaquetto DE, Rueda-Torres L, Bailon N, Barreto PV, Málaga G. Accuracy of HemoCue301 portable hemoglobin analyzer for anemia screening in capillary blood from women of reproductive age in a deprived region of Northern Peru: An on-field study. PloS one 2023. link 45 Bronkhorst-van der Helm MW, Weerkamp F, Huisman A, Huisman EJ, Russcher H. Interference of bovine hemoglobin-based oxygen carrier-201 (Hemopure) on four hematology analyzers. International journal of laboratory hematology 2023. link 46 Moloney C, Stavroulaki EM, Augusto M. Reference intervals for reticulocyte indices, immature reticulocyte fraction, and the percentage of hypochromic red blood cells in adult large breed dogs using the ADVIA 2120 hematology analyzer. Veterinary clinical pathology 2023. link 47 Kim MS, Park CJ, Namgoong S, Kim SI, Cho YU, Jang S. Effective and Practical Complete Blood Count Delta Check Method and Criteria for the Quality Control of Automated Hematology Analyzers. Annals of laboratory medicine 2023. link 48 Wiesenack C, Meybohm P, Neef V, Kranke P. Current concepts in preoperative anemia management in obstetrics. Current opinion in anaesthesiology 2023. link 49 Cozzi GD, Blanchard CT, Edwards JT, Szychowski JM, Subramaniam A, Battarbee AN. Optimal predelivery hemoglobin to reduce transfusion and adverse perinatal outcomes. American journal of obstetrics & gynecology MFM 2023. link 50 Singh SK, Lhungdim H, Shekhar C, Dwivedi LK, Pedgaonkar S, James KS. Key drivers of reversal of trend in childhood anaemia in India: evidence from Indian demographic and health surveys, 2016-21. BMC public health 2023. link 51 Young MF, Nguyen P, Tran LM, Khuong LQ, Martorell R, Ramakrishnan U. Long-Term Association Between Maternal Preconception Hemoglobin Concentration, Anemia, and Child Health and Development in Vietnam. The Journal of nutrition 2023. link 52 Mayasari NR, Bai CH, Chao JC, Chen YC, Huang YL, Wang FF et al.. Relationships between Dietary Patterns and Erythropoiesis-Associated Micronutrient Deficiencies (Iron, Folate, and Vitamin B. Nutrients 2023. link 53 Vaccaro JA, Qasem A, Naser SA. Folate and Vitamin B. Nutrients 2023. link 54 Zhang L, Huang A, Cai J, Hou J, Deng H, Liu C. Bionics investigation of blood 25-hydroxyvitamin D in the interpretable biomechanics diagnosis of childhood anemia. Acta biochimica Polonica 2023. link 55 Loganathan V, Bharathi A, Prince AM, Ramakrishnan J. Treatment efficacy of vitamin C or ascorbate given as co-intervention with iron for anemia - A systematic review and meta-analysis of experimental studies. Clinical nutrition ESPEN 2023. link 56 Pons-Belda OD, Alonso-Álvarez MA, González-Rodríguez JD, Mantecón-Fernández L, Santos-Rodríguez F. Mineral Metabolism in Children: Interrelation between Vitamin D and FGF23. International journal of molecular sciences 2023. link 57 Chin K, Joo H, Jiang H, Lin C, Savinova I, Joo S et al.. Importance of assessing biomarkers and physiological parameters of anemia-induced tissue hypoxia in the perioperative period. Brazilian journal of anesthesiology (Elsevier) 2023. link 58 Carson JL, Brittenham GM. How I treat anemia with red blood cell transfusion and iron. Blood 2023. link 59 Karami M, Chaleshgar M, Salari N, Akbari H, Mohammadi M. Global Prevalence of Anemia in Pregnant Women: A Comprehensive Systematic Review and Meta-Analysis. Maternal and child health journal 2022. link 60 Lima MS, Pereira M, Castro CT, Santos DB. Vitamin D deficiency and anemia in pregnant women: a systematic review and meta-analysis. Nutrition reviews 2022. link 61 Habtegiorgis SD, Petrucka P, Telayneh AT, Getahun DS, Getacher L, Alemu S et al.. Prevalence and associated factors of anemia among adolescent girls in Ethiopia: A systematic review and meta-analysis. PloS one 2022. link 62 Ozdemir S. Report of a Case with Profound Anaemia from Health Literacy Perspective. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2022. link 63 Wang W, Li ZP, Zhang J, Lin ZJ, Ma ML, Chen SS. Comment "Asymptomatic small intestinal ulcerative lesions: Obesity and . World journal of gastroenterology 2022. link 64 Kramer RM, Sheh A, Toolan CH, Muthupalani S, Carrasco SE, Artim SC et al.. Factors Affecting Hematologic and Serum Biochemical Parameters in Healthy Common Marmosets (. Journal of the American Association for Laboratory Animal Science : JAALAS 2022. link 65 Bianchi I, Stefani CJM, Santiago P, Zanatta AL, Rieder R. AnemiaAR: a serious game to support teaching of haematology. Journal of visual communication in medicine 2022. link 66 Lollie TK, Parks R, Bakic L, Ziman A, Pullarkat S. Educational cost-effective intervention to reduce pathologist's peripheral blood smears reviews with non-contributory findings: an academic institution experience. Journal of clinical pathology 2022. link 67 Yahagi K, Arai T, Katagiri H, Yatabe Y, Yokota H, Nagai Y et al.. Performance evaluation of a novel reticulocyte identification method that uses metachromatic nucleic acid staining based on a crossover analysis of emission DNA/RNA light (RNP Determination™) in hematology analyzer Celltac G. International journal of laboratory hematology 2022. link 68 Gasparin AT, Araujo CIF, Schmitt P, Cardoso MR, Perussolo MC, de Jesus TCS et al.. Hilab system, a new point-of-care hematology analyzer supported by the Internet of Things and Artificial Intelligence. Scientific reports 2022. link 69 Chandra J, Dewan P, Kumar P, Mahajan A, Singh P, Dhingra B et al.. Diagnosis, Treatment and Prevention of Nutritional Anemia in Children: Recommendations of the Joint Committee of Pediatric Hematology-Oncology Chapter and Pediatric and Adolescent Nutrition Society of the Indian Academy of Pediatrics. Indian pediatrics 2022. link 70 Seifu CN, Fahey PP, Atlantis E. Micronutrient deficiencies and anaemia associated with body mass index in Australian adults: a cross-sectional study. BMJ open 2022. link 71 Wiedemann A, Oussalah A, Lamireau N, Théron M, Julien M, Mergnac JP et al.. Clinical, phenotypic and genetic landscape of case reports with genetically proven inherited disorders of vitamin B. Cell reports. Medicine 2022. link 72 Chakraborty A, Minor KE, Nizami HL, Chiao YA, Lee CF. Harnessing NAD. Current heart failure reports 2022. link 73 Shah AA, Donovan K, Seeley C, Dickson EA, Palmer AJR, Doree C et al.. Risk of Infection Associated With Administration of Intravenous Iron: A Systematic Review and Meta-analysis. JAMA network open 2021. link 74 Byrne A, Manalo G, Clarke NE, Vaz Nery S. Impact of hookworm infection and preventive chemotherapy on haemoglobin in non-pregnant populations. Tropical medicine & international health : TM & IH 2021. link 75 Bell S, Rigas AS, Magnusson MK, Ferkingstad E, Allara E, Bjornsdottir G et al.. A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis. Communications biology 2021. link 76 Ferreira HS, Vieira RCS, Livramento ARS, Dourado BLL, Silva GF, Calheiros MSC. Prevalence of anaemia in Brazilian children in different epidemiological scenarios: an updated meta-analysis. Public health nutrition 2021. link 77 Tyrrell L, Rose G, Shukri A, Kahwash SB. Morphologic changes in red blood cells: An illustrated review of clinically important light microscopic findings. The Malaysian journal of pathology 2021. link 78 Wang N, Jiang J, Wang J, He Y, Wen N, Liu Y et al.. Detection of nucleated red blood cells using the Mindray BC-6800Plus hematology analyzer: a clinical performance evaluation. Annals of palliative medicine 2021. link 79 Hirani R, Mondy P. Review of full blood count reference interval using a large cohort of first-time plasmapheresis blood donors. Pathology 2021. link 80 Leung E, Johnston A, Olsen B, Chang H, Martin T, Wozniak M et al.. Laboratory practices for manual blood film review: Results of an IQMH patterns of practice survey. International journal of laboratory hematology 2021. link 81 Son M, Lee YS, Lee MJ, Park Y, Bae HR, Lee SY et al.. Effects of osmolality and solutes on the morphology of red blood cells according to three-dimensional refractive index tomography. PloS one 2021. link 82 Kee YK, Jeon HJ, Oh J, Shin DH. Hypochromic red cells as predictors of anemia in patients undergoing hemodialysis: an observational retrospective study. Scientific reports 2021. link 83 Heesemann E, Mähler C, Subramanyam MA, Vollmer S. Pregnancy anaemia, child health and development: a cohort study in rural India. BMJ open 2021. link 84 Kumar KS, Saini AG, Attri SV, Bharti B, Sankhyan N, Bhatia P. Assessment of Vitamin B. Indian journal of pediatrics 2021. link 85 Tchum SK, Arthur FK, Adu B, Sakyi SA, Abubakar LA, Atibilla D et al.. Impact of iron fortification on anaemia and iron deficiency among pre-school children living in Rural Ghana. PloS one 2021. link 86 Gupta A, Kant S, Ramakrishnan L, Pandey RM, Khandelwal R, Kapil U et al.. Impact of daily-supervised administration of a package of iron and folic acid and vitamin B. European journal of clinical nutrition 2021. link 87 Communi D, Horckmans M, Boeynaems JM. P2Y. Biochemical pharmacology 2021. link 88 Zhao L, Qiu X, Wang R, Wang D. (no title). Journal of pharmaceutical and biomedical analysis 2021. link 89 Juffrie M, Helmyati S, Hakimi M. Nutritional anemia in Indonesia children and adolescents: Diagnostic reliability for appropriate management. Asia Pacific journal of clinical nutrition 2020. link.03) 90 Garraud O, Vuk T, Brand A, de Angelis V, Politis C, Haddad A et al.. Medical student education in transfusion medicine, part II: Moving forward to building up a "Know How" education program in transfusion medicine for under-graduate medical students. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2020. link 91 Briguglio M, Hrelia S, Malaguti M, De Vecchi E, Lombardi G, Banfi G et al.. Oral Supplementation with Sucrosomial Ferric Pyrophosphate Plus L-Ascorbic Acid to Ameliorate the Martial Status: A Randomized Controlled Trial. Nutrients 2020. link 92 Pérez I, Redín ME. Red Blood Cells and Platelets Conventional and Research Parameters: Stability Remarks Before Their Interpretation. Laboratory medicine 2020. link 93 Bolcato M, Russo M, Trentino K, Isbister J, Rodriguez D, Aprile A. Patient blood management: The best approach to transfusion medicine risk management. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2020. link 94 Katsogiannou EG, Athanasiou LV, Katsoulos PD, Polizopoulou ZS, Tzivara A, Christodoulopoulos G. Estimation of white blood cell and platelet counts in ovine blood smears, and a comparison with the ADVIA 120 hematology analyzer. Veterinary clinical pathology 2020. link 95 Bharati S, Pal M, Bharati P. Prevalence of anaemia among 6- to 59-month-old children in India: the latest picture through the NFHS-4. Journal of biosocial science 2020. link 96 Sullivan JA, AlAdra DP, Olson BM, McNeel DG, Burlingham WJ. Infectious Tolerance as Seen With 2020 Vision: The Role of IL-35 and Extracellular Vesicles. Frontiers in immunology 2020. link 97 Rössler J, Hegemann I, Schoenrath F, Seifert B, Kaserer A, Spahn GH et al.. Efficacy of quadruple treatment on different types of pre-operative anaemia: secondary analysis of a randomised controlled trial. Anaesthesia 2020. link 98 Briguglio M, Hrelia S, Malaguti M, Lombardi G, Riso P, Porrini M et al.. The Central Role of Iron in Human Nutrition: From Folk to Contemporary Medicine. Nutrients 2020. link 99 Shen Y, Lim CJ, Lee SY, Ryu PD. Acute Anemia Induces Erythropoiesis in Rat Organ Surface Primo-Vascular Tissue. Advances in experimental medicine and biology 2020. link 100 Mueller MM, Van Remoortel H, Meybohm P, Aranko K, Aubron C, Burger R et al.. Patient Blood Management: Recommendations From the 2018 Frankfurt Consensus Conference. JAMA 2019. link

    Original source

    1. [1]
      Artificial Intelligence Implementation in Transfusion Medicine: Addressing the Challenges of Clinical Adoption.Maynard S, Farrington J, Raza S, Stanworth SJ Transfusion medicine reviews (2026)
    2. [2]
      Clinical Evaluation of a Novel Point-of-Care Hematology Analyzer for Complete Blood Count With Differential.Shean RC, Bennett ST International journal of laboratory hematology (2026)
    3. [3]
      Challenges and opportunities of wearable molecular sensors in endocrinology and metabolism.Güntner AT, Gerber PA, Dittrich PS, Serra N, Figalli A, Puhan MA et al. Nature reviews. Endocrinology (2026)
    4. [4]
      Clinical Utility of Monoclonal Gammopathy Testing in the Evaluation of Anemia.Maberry MD, Smith CJ, Go RS American journal of hematology (2026)
    5. [5]
      Non-invasive hemoglobin estimation with outcome prediction via deep learning analysis of ECG-derived cardiac micro-dynamics.Yang CC, Lin CS, Lin C, Liu WT, Lai ZY, Chuang YJ Internal and emergency medicine (2026)
    6. [6]
      Do Cash Transfer Programmes Affect Child Anaemia? Results From a Meta-Analysis.Manley J, Alderman H Maternal & child nutrition (2025)
    7. [7]
      FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH).Ubom AE, Begum F, Ramasauskaite D, Nieto-Calvache AJ, Oguttu M, Nunes I et al. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2025)
    8. [8]
    9. [9]
      Assessment of Recipient Characteristics and Blood Product Usage Patterns at the Transfusion Medicine Institute of FBiH in 2023.Catovic-Baralija E Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina (2025)
    10. [10]
      Advances in the characterization of in vitro-generated red blood cells: from biophysical properties to functional applications.Jang Y, Eom YJ, Gwak SH, Koh Y, Han J, Rim YA et al. Stem cell research & therapy (2025)
    11. [11]
    12. [12]
      Vitamin D supplementation ameliorates anemia of inflammation by reducing hepcidin levels and inactivating inflammatory signaling pathways.Xu P, Liu G, Chen B Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion (2025)
    13. [13]
    14. [14]
      The Role of NADLi H, Hu Q, Zhu D, Wu D American journal of cardiovascular drugs : drugs, devices, and other interventions (2025)
    15. [15]
      Identification and management of preoperative anaemia in adults: A British Society for Haematology Guideline update.Hands K, Daru J, Evans C, Kotze A, Lewis C, Narayan S et al. British journal of haematology (2024)
    16. [16]
      The Prevalence of Anemia among Pregnant Women in China: A Systematic Review and Meta-Analysis.Zhou Y, Lyu Y, Ye W, Shi H, Peng Y, Wen Z et al. Nutrients (2024)
    17. [17]
      The association between maternal anemia and neonatal anemia: a systematic review and meta-analysis.Zhao B, Sun M, Wu T, Li J, Shi H, Wei Y BMC pregnancy and childbirth (2024)
    18. [18]
    19. [19]
      Advances in Hematology Analyzers Technology.Shean RC, Williams MC, Rets AV Clinics in laboratory medicine (2024)
    20. [20]
      Molecular Research of Regulation of Red Blood Cells in Health, Hereditary or Acquired Diseases.Wautier JL International journal of molecular sciences (2024)
    21. [21]
      Evaluating patient blood management practices using PBM metrics in a tertiary care center.George A, Shastry S, Mohan G, Belurkar S Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine (2024)
    22. [22]
      Anemia and Transfusion Medicine.Kalra SK, Auron M The Medical clinics of North America (2024)
    23. [23]
      Advancing in vivo assessment of red blood cell transfusions: A call for radiation-free methods in transfusion medicine.Yazdanbakhsh M, Acker JP Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis (2024)
    24. [24]
      Report of the International Council for Standardization in Haematology working group for standardization of reticulocyte parameters.Obstfeld AE, Davis BH, Han JY, Urrechaga E International journal of laboratory hematology (2024)
    25. [25]
      Prevalence, risk factors, and treatment of anemia in hospitalized older patients across geriatric and nephrological settings in Italy.Soraci L, de Vincentis A, Aucella F, Fabbietti P, Corsonello A, Arena E et al. Scientific reports (2024)
    26. [26]
    27. [27]
    28. [28]
      Vitamin BLiu L, Zhou J, Chen C, Qu Y, Wang J, Lu F et al. BMC geriatrics (2024)
    29. [29]
      Impact of supplementation with iron-folic acid (IFA) and vitamin DAhamed F, Jaiswal A, Sahoo S, Ghosh T, Kaur A, Rehman T et al. BMJ open (2024)
    30. [30]
    31. [31]
      Relationship between anemia and occupational fall injuries in female part-time employees: an observational study of large supermarket stores in Japan.Shima A, Kawatsu Y, Morino A, Okawara M, Hirashima K, Miyamatsu N et al. Journal of occupational health (2024)
    32. [32]
    33. [33]
      Intravenous Iron Therapy to Treat Anemia in Oncology: A Mapping Review of Randomized Controlled Trials.Lim J, Auerbach M, MacLean B, Al-Sharea A, Richards T Current oncology (Toronto, Ont.) (2023)
    34. [34]
    35. [35]
    36. [36]
      Prevalence of Anemia among Children and Adolescents of Bangladesh: A Systematic Review and Meta-Analysis.Kundu S, Alam SS, Mia MA, Hossan T, Hider P, Khalil MI et al. International journal of environmental research and public health (2023)
    37. [37]
      Iron oxide nanoparticles carried by probiotics for iron absorption: a systematic review.Ciont C, Mesaroș A, Pop OL, Vodnar DC Journal of nanobiotechnology (2023)
    38. [38]
      Perioperative management of patients with anaemia: a new guideline.McNally SA British journal of hospital medicine (London, England : 2005) (2023)
    39. [39]
      Splenosis as an incidental finding in a patient with multifactorial anemia.Prieto García B, González Santiago JM, Gómez-Caminero López F Revista espanola de enfermedades digestivas (2023)
    40. [40]
      Prevalence of anaemia in acutely unwell infants.Park JY, Grant CC The New Zealand medical journal (2023)
    41. [41]
      Analysis of haematological effects of Picralima nitida.Ufelle Silas Anayo -, Onyekwelu Kenechukwu -, Chikwendu Chiedozie Kenechi - Pakistan journal of pharmaceutical sciences (2023)
    42. [42]
      Red Blood Cell Storage: From Genome to Exposome Towards Personalized Transfusion Medicine.D'Alessandro A, Hod EA Transfusion medicine reviews (2023)
    43. [43]
    44. [44]
    45. [45]
      Interference of bovine hemoglobin-based oxygen carrier-201 (Hemopure) on four hematology analyzers.Bronkhorst-van der Helm MW, Weerkamp F, Huisman A, Huisman EJ, Russcher H International journal of laboratory hematology (2023)
    46. [46]
    47. [47]
      Effective and Practical Complete Blood Count Delta Check Method and Criteria for the Quality Control of Automated Hematology Analyzers.Kim MS, Park CJ, Namgoong S, Kim SI, Cho YU, Jang S Annals of laboratory medicine (2023)
    48. [48]
      Current concepts in preoperative anemia management in obstetrics.Wiesenack C, Meybohm P, Neef V, Kranke P Current opinion in anaesthesiology (2023)
    49. [49]
      Optimal predelivery hemoglobin to reduce transfusion and adverse perinatal outcomes.Cozzi GD, Blanchard CT, Edwards JT, Szychowski JM, Subramaniam A, Battarbee AN American journal of obstetrics & gynecology MFM (2023)
    50. [50]
      Key drivers of reversal of trend in childhood anaemia in India: evidence from Indian demographic and health surveys, 2016-21.Singh SK, Lhungdim H, Shekhar C, Dwivedi LK, Pedgaonkar S, James KS BMC public health (2023)
    51. [51]
      Long-Term Association Between Maternal Preconception Hemoglobin Concentration, Anemia, and Child Health and Development in Vietnam.Young MF, Nguyen P, Tran LM, Khuong LQ, Martorell R, Ramakrishnan U The Journal of nutrition (2023)
    52. [52]
      Relationships between Dietary Patterns and Erythropoiesis-Associated Micronutrient Deficiencies (Iron, Folate, and Vitamin BMayasari NR, Bai CH, Chao JC, Chen YC, Huang YL, Wang FF et al. Nutrients (2023)
    53. [53]
      Folate and Vitamin BVaccaro JA, Qasem A, Naser SA Nutrients (2023)
    54. [54]
      Bionics investigation of blood 25-hydroxyvitamin D in the interpretable biomechanics diagnosis of childhood anemia.Zhang L, Huang A, Cai J, Hou J, Deng H, Liu C Acta biochimica Polonica (2023)
    55. [55]
    56. [56]
      Mineral Metabolism in Children: Interrelation between Vitamin D and FGF23.Pons-Belda OD, Alonso-Álvarez MA, González-Rodríguez JD, Mantecón-Fernández L, Santos-Rodríguez F International journal of molecular sciences (2023)
    57. [57]
      Importance of assessing biomarkers and physiological parameters of anemia-induced tissue hypoxia in the perioperative period.Chin K, Joo H, Jiang H, Lin C, Savinova I, Joo S et al. Brazilian journal of anesthesiology (Elsevier) (2023)
    58. [58]
      How I treat anemia with red blood cell transfusion and iron.Carson JL, Brittenham GM Blood (2023)
    59. [59]
      Global Prevalence of Anemia in Pregnant Women: A Comprehensive Systematic Review and Meta-Analysis.Karami M, Chaleshgar M, Salari N, Akbari H, Mohammadi M Maternal and child health journal (2022)
    60. [60]
      Vitamin D deficiency and anemia in pregnant women: a systematic review and meta-analysis.Lima MS, Pereira M, Castro CT, Santos DB Nutrition reviews (2022)
    61. [61]
      Prevalence and associated factors of anemia among adolescent girls in Ethiopia: A systematic review and meta-analysis.Habtegiorgis SD, Petrucka P, Telayneh AT, Getahun DS, Getacher L, Alemu S et al. PloS one (2022)
    62. [62]
      Report of a Case with Profound Anaemia from Health Literacy Perspective.Ozdemir S Journal of the College of Physicians and Surgeons--Pakistan : JCPSP (2022)
    63. [63]
      Comment "Asymptomatic small intestinal ulcerative lesions: Obesity and Wang W, Li ZP, Zhang J, Lin ZJ, Ma ML, Chen SS World journal of gastroenterology (2022)
    64. [64]
      Factors Affecting Hematologic and Serum Biochemical Parameters in Healthy Common Marmosets (Kramer RM, Sheh A, Toolan CH, Muthupalani S, Carrasco SE, Artim SC et al. Journal of the American Association for Laboratory Animal Science : JAALAS (2022)
    65. [65]
      AnemiaAR: a serious game to support teaching of haematology.Bianchi I, Stefani CJM, Santiago P, Zanatta AL, Rieder R Journal of visual communication in medicine (2022)
    66. [66]
    67. [67]
    68. [68]
      Hilab system, a new point-of-care hematology analyzer supported by the Internet of Things and Artificial Intelligence.Gasparin AT, Araujo CIF, Schmitt P, Cardoso MR, Perussolo MC, de Jesus TCS et al. Scientific reports (2022)
    69. [69]
    70. [70]
    71. [71]
      Clinical, phenotypic and genetic landscape of case reports with genetically proven inherited disorders of vitamin BWiedemann A, Oussalah A, Lamireau N, Théron M, Julien M, Mergnac JP et al. Cell reports. Medicine (2022)
    72. [72]
      Harnessing NADChakraborty A, Minor KE, Nizami HL, Chiao YA, Lee CF Current heart failure reports (2022)
    73. [73]
      Risk of Infection Associated With Administration of Intravenous Iron: A Systematic Review and Meta-analysis.Shah AA, Donovan K, Seeley C, Dickson EA, Palmer AJR, Doree C et al. JAMA network open (2021)
    74. [74]
      Impact of hookworm infection and preventive chemotherapy on haemoglobin in non-pregnant populations.Byrne A, Manalo G, Clarke NE, Vaz Nery S Tropical medicine & international health : TM & IH (2021)
    75. [75]
      A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.Bell S, Rigas AS, Magnusson MK, Ferkingstad E, Allara E, Bjornsdottir G et al. Communications biology (2021)
    76. [76]
      Prevalence of anaemia in Brazilian children in different epidemiological scenarios: an updated meta-analysis.Ferreira HS, Vieira RCS, Livramento ARS, Dourado BLL, Silva GF, Calheiros MSC Public health nutrition (2021)
    77. [77]
      Morphologic changes in red blood cells: An illustrated review of clinically important light microscopic findings.Tyrrell L, Rose G, Shukri A, Kahwash SB The Malaysian journal of pathology (2021)
    78. [78]
      Detection of nucleated red blood cells using the Mindray BC-6800Plus hematology analyzer: a clinical performance evaluation.Wang N, Jiang J, Wang J, He Y, Wen N, Liu Y et al. Annals of palliative medicine (2021)
    79. [79]
    80. [80]
      Laboratory practices for manual blood film review: Results of an IQMH patterns of practice survey.Leung E, Johnston A, Olsen B, Chang H, Martin T, Wozniak M et al. International journal of laboratory hematology (2021)
    81. [81]
    82. [82]
    83. [83]
      Pregnancy anaemia, child health and development: a cohort study in rural India.Heesemann E, Mähler C, Subramanyam MA, Vollmer S BMJ open (2021)
    84. [84]
      Assessment of Vitamin BKumar KS, Saini AG, Attri SV, Bharti B, Sankhyan N, Bhatia P Indian journal of pediatrics (2021)
    85. [85]
      Impact of iron fortification on anaemia and iron deficiency among pre-school children living in Rural Ghana.Tchum SK, Arthur FK, Adu B, Sakyi SA, Abubakar LA, Atibilla D et al. PloS one (2021)
    86. [86]
      Impact of daily-supervised administration of a package of iron and folic acid and vitamin BGupta A, Kant S, Ramakrishnan L, Pandey RM, Khandelwal R, Kapil U et al. European journal of clinical nutrition (2021)
    87. [87]
      P2YCommuni D, Horckmans M, Boeynaems JM Biochemical pharmacology (2021)
    88. [88]
      (no title)Zhao L, Qiu X, Wang R, Wang D Journal of pharmaceutical and biomedical analysis (2021)
    89. [89]
      Nutritional anemia in Indonesia children and adolescents: Diagnostic reliability for appropriate management.Juffrie M, Helmyati S, Hakimi M Asia Pacific journal of clinical nutrition (2020)
    90. [90]
      Medical student education in transfusion medicine, part II: Moving forward to building up a "Know How" education program in transfusion medicine for under-graduate medical students.Garraud O, Vuk T, Brand A, de Angelis V, Politis C, Haddad A et al. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis (2020)
    91. [91]
      Oral Supplementation with Sucrosomial Ferric Pyrophosphate Plus L-Ascorbic Acid to Ameliorate the Martial Status: A Randomized Controlled Trial.Briguglio M, Hrelia S, Malaguti M, De Vecchi E, Lombardi G, Banfi G et al. Nutrients (2020)
    92. [92]
    93. [93]
      Patient blood management: The best approach to transfusion medicine risk management.Bolcato M, Russo M, Trentino K, Isbister J, Rodriguez D, Aprile A Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis (2020)
    94. [94]
      Estimation of white blood cell and platelet counts in ovine blood smears, and a comparison with the ADVIA 120 hematology analyzer.Katsogiannou EG, Athanasiou LV, Katsoulos PD, Polizopoulou ZS, Tzivara A, Christodoulopoulos G Veterinary clinical pathology (2020)
    95. [95]
    96. [96]
      Infectious Tolerance as Seen With 2020 Vision: The Role of IL-35 and Extracellular Vesicles.Sullivan JA, AlAdra DP, Olson BM, McNeel DG, Burlingham WJ Frontiers in immunology (2020)
    97. [97]
      Efficacy of quadruple treatment on different types of pre-operative anaemia: secondary analysis of a randomised controlled trial.Rössler J, Hegemann I, Schoenrath F, Seifert B, Kaserer A, Spahn GH et al. Anaesthesia (2020)
    98. [98]
      The Central Role of Iron in Human Nutrition: From Folk to Contemporary Medicine.Briguglio M, Hrelia S, Malaguti M, Lombardi G, Riso P, Porrini M et al. Nutrients (2020)
    99. [99]
      Acute Anemia Induces Erythropoiesis in Rat Organ Surface Primo-Vascular Tissue.Shen Y, Lim CJ, Lee SY, Ryu PD Advances in experimental medicine and biology (2020)
    100. [100]
      Patient Blood Management: Recommendations From the 2018 Frankfurt Consensus Conference.Mueller MM, Van Remoortel H, Meybohm P, Aranko K, Aubron C, Burger R et al. JAMA (2019)

    HemoChat

    by SPINAI

    Evidence-based clinical decision support powered by SNOMED-CT, Neo4j GraphRAG, and NASS/AO/NICE guidelines.

    ⚕ For clinical reference only. Not a substitute for professional judgment.

    © 2026 HemoChat. All rights reserved.
    Research·Pricing·Privacy & Terms·Refund·SNOMED-CT · NASS · AO Spine · NICE · GraphRAG