Overview
Thickened vocal cords often indicate underlying pathology such as malignancy or post-treatment changes, impacting voice quality and potentially necessitating intervention. 1Diagnosis
Imaging: CT or MRI to assess extent and involvement 1
Direct laryngoscopy: Essential for visual assessment and biopsy if malignancy suspected 1
Histopathology: Confirms diagnosis, particularly for cancer staging 1
Grading: TNM staging system applied for malignancies 1Management
Primary Treatment: Radiotherapy for early glottic cancer (Stages I and II) 1
Salvage Surgery: Laryngectomy for local recurrence post-radiotherapy 1
Follow-up: Regular laryngoscopy to monitor for recurrence 1Special Populations
No specific data: The provided abstract does not cover management in pregnancy, pediatrics, elderly, or patients with comorbidities 1Key Recommendations
Use radical radiotherapy as primary treatment for early glottic cancer (Stages I and II) to achieve high local tumor control rates and survival (Evidence: Strong 1)
Consider salvage laryngectomy for patients with local recurrence post-radiotherapy to manage persistent disease effectively (Evidence: Moderate 1)
Implement regular follow-up with laryngoscopy to monitor for recurrence and ensure early detection (Evidence: Expert opinion 1)References
1 Kardell WD, Kearsley JH, Donovan JK. Radiotherapy in the treatment of carcinoma of the vocal cords: results of a 10-year experience. The Medical journal of Australia 1982. link