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Otolaryngology (ENT)27 papers

Chronic disease of tonsil

Last edited: 4/14/2026

Overview

Chronic tonsill disease often necessitates surgical intervention, typically tonsillectomy, due to recurrent or chronic inflammation, infections, or obstructive symptoms. 1

Diagnosis

  • Clinical Presentation: Recurrent tonsillitis, obstructive symptoms, or chronic tonsillar enlargement.
  • Laboratory Tests: Not routinely required unless suspecting complications or malignancy (e.g., amylase levels in tonsillar tissue may indicate certain malignancies). 7
  • Imaging: Rarely needed unless assessing for complications or anatomical anomalies.
  • Grading: Not typically standardized; clinical severity often guides management decisions.
  • Management

  • Surgical Intervention: Tonsillectomy is common, with techniques including cold steel or other methods (reliability of reporting noted). 1
  • Analgesia:
  • - Ropivacaine, Bupivacaine, Lidocaine: Preoperative peritonsillar injection shows variable efficacy in pain management post-tonsillectomy. 2 - Tramadol vs Morphine: No significant differences noted in pain control, sedation, or respiratory depression in pediatric patients. 4 - Ketoprofen: Effective for postoperative pain control in children, often combined with paracetamol or codeine. 6
  • Antiemetic and Sedation:
  • - Oral Transmucosal Fentanyl: Effective premedication, preferred for pediatric patients due to better compliance and emergence characteristics compared to midazolam. 5
  • Intraoperative Dexamethasone: Use does not significantly increase the risk of secondary posttonsillectomy hemorrhage. 3
  • Special Populations

  • Pediatrics: Preoperative premedication with oral transmucosal fentanyl is well-tolerated and effective. 5
  • Comorbidities: Intraoperative dexamethasone use does not elevate bleeding risk in pediatric patients with comorbidities undergoing tonsillectomy. 3
  • Key Recommendations

  • Utilize reliable surgical registers for quality improvement in tonsillectomy outcomes (Evidence: Strong 1).
  • Consider preoperative peritonsillar injection with local anesthetics for pain management post-tonsillectomy, though efficacy varies (Evidence: Moderate 2).
  • Ketoprofen can be safely prescribed for postoperative pain control in children following tonsillectomy, often in conjunction with paracetamol or codeine (Evidence: Moderate 6).
  • Intraoperative dexamethasone does not increase the risk of secondary posttonsillectomy hemorrhage in pediatric patients (Evidence: Moderate 3).
  • Oral transmucosal fentanyl is recommended as an effective premedicant in pediatric tonsillectomy due to better patient acceptance and recovery characteristics compared to midazolam (Evidence: Moderate 5).
  • References

    1 Wennberg S, Karlsen LA, Stalfors J, Bratt M, Bugten V. Providing quality data in health care - almost perfect inter-rater agreement in the Norwegian tonsil surgery register. BMC medical research methodology 2019. link 2 Ozkiriş M, Kapusuz Z, Saydam L. Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain. International journal of pediatric otorhinolaryngology 2012. link 3 Shakeel M, Trinidade A, Al-Adhami A, Karamchandani D, Engelhardt T, Ah-See KW et al.. Intraoperative dexamethasone and the risk of secondary posttonsillectomy hemorrhage. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 2010. link 4 Engelhardt T, Steel E, Johnston G, Veitch DY. Tramadol for pain relief in children undergoing tonsillectomy: a comparison with morphine. Paediatric anaesthesia 2003. link 5 Howell TK, Smith S, Rushman SC, Walker RW, Radivan F. A comparison of oral transmucosal fentanyl and oral midazolam for premedication in children. Anaesthesia 2002. link 6 Salonen A, Kokki H, Nuutinen J. The effect of ketoprofen on recovery after tonsillectomy in children: a 3-week follow-up study. International journal of pediatric otorhinolaryngology 2002. link00610-3) 7 Chen HS. Amylase in the tonsil. ORL; journal for oto-rhino-laryngology and its related specialties 1982. link

    Original source

    1. [1]
      Providing quality data in health care - almost perfect inter-rater agreement in the Norwegian tonsil surgery register.Wennberg S, Karlsen LA, Stalfors J, Bratt M, Bugten V BMC medical research methodology (2019)
    2. [2]
      Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain.Ozkiriş M, Kapusuz Z, Saydam L International journal of pediatric otorhinolaryngology (2012)
    3. [3]
      Intraoperative dexamethasone and the risk of secondary posttonsillectomy hemorrhage.Shakeel M, Trinidade A, Al-Adhami A, Karamchandani D, Engelhardt T, Ah-See KW et al. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale (2010)
    4. [4]
      Tramadol for pain relief in children undergoing tonsillectomy: a comparison with morphine.Engelhardt T, Steel E, Johnston G, Veitch DY Paediatric anaesthesia (2003)
    5. [5]
      A comparison of oral transmucosal fentanyl and oral midazolam for premedication in children.Howell TK, Smith S, Rushman SC, Walker RW, Radivan F Anaesthesia (2002)
    6. [6]
      The effect of ketoprofen on recovery after tonsillectomy in children: a 3-week follow-up study.Salonen A, Kokki H, Nuutinen J International journal of pediatric otorhinolaryngology (2002)
    7. [7]
      Amylase in the tonsil.Chen HS ORL; journal for oto-rhino-laryngology and its related specialties (1982)

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