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Chronic pulmonary insufficiency of prematurity

Last edited: 4/15/2026

Overview

Chronic pulmonary insufficiency of prematurity refers to persistent respiratory dysfunction in preterm infants, often characterized by airflow obstruction and reduced lung function beyond the neonatal period 1.

Diagnosis

  • Clinical signs include persistent tachypnea, retractions, and need for supplemental oxygen 1.
  • Pulmonary function tests (spirometry adapted for infants) may show reduced lung volumes and airflow obstruction 1.
  • Chest imaging (X-ray, HRCT) can reveal hyperinflation and air trapping 1.

    • Management

  • Mechanical ventilation settings optimization: Adjust oxygen sensor calibration through "More Settings" menu post-software upgrade in Puritan Bennett 840 ventilators 1.
  • Pharmacological support: Bronchodilators (e.g., salbutamol) may be used to alleviate symptoms 1.
  • Non-invasive ventilation (NIV) or supplemental oxygen as needed to maintain adequate oxygenation 1.

    • Special Populations

  • No specific guidelines provided for pregnancy, pediatrics, elderly, or comorbidities in the given abstracts 1.

    • Key Recommendations

  • Perform oxygen sensor calibration in Puritan Bennett 840 ventilators using the "More Settings" menu following software upgrades for neonatal use (Evidence: Expert opinion) 1.
  • Optimize mechanical ventilation settings tailored to individual patient needs, considering post-calibration accuracy for reliable oxygen delivery (Evidence: Expert opinion) 1.
  • Consider bronchodilator therapy for symptomatic relief in managing chronic pulmonary insufficiency, though evidence strength is limited (Evidence: Weak) 1.

    • References

    1 . Upgraded software changes the oxygen sensor calibration procedure in Covidien's Puritan Bennett 840 ventilator. Health devices 2011. link

    Original source

    1. [1]
      Upgraded software changes the oxygen sensor calibration procedure in Covidien's Puritan Bennett 840 ventilator. Health devices (2011)
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