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Neurology7 papers

Notalgia paresthetica

Last edited: 4/15/2026

Overview

Notalgia paresthetica is a sensory neuropathy characterized by localized pruritus and pain, often accompanied by hyperpigmentation and abnormal sensations in the upper back, typically involving thoracic nerves T2 through T6 12.

Diagnosis

  • Clinical Presentation: Localized pruritus, pain, burning, numbness, and paresthesia in the upper back 12.
  • Physical Examination: Presence of hyperpigmented patches may be noted 1.
  • Imaging: Radiography and magnetic resonance imaging (MRI) of the spine can rule out other spinal pathologies 1.
  • Severity Assessment: Use Visual Analog Scale (VAS) for pain and pruritus intensity 1.
  • Management

  • First-Line Treatments:
  • - Topical Agents: Not specifically detailed in abstracts, but commonly used. - Intradermal Lidocaine Injections: Diluted 2% lidocaine (1 cc diluted with 5 cc 0.9% saline, total 6 cc administered over three sessions) shows promise 1.
  • Adjunctive Treatments:
  • - Physical Therapy: Not detailed in provided abstracts. - Psychological Support: Consideration for chronic pruritus management, though not explicitly mentioned 1.

    Special Populations

  • No Specific Data: Limited information on management in pregnancy, pediatrics, elderly, or with comorbidities from the provided abstracts 12.
  • Key Recommendations

  • Evaluate with Imaging: Utilize radiography and MRI to exclude other spinal causes of symptoms (Evidence: Moderate 1).
  • Consider Intradermal Lidocaine: Intradermal lidocaine injections may be effective for symptom relief; administer diluted lidocaine over multiple sessions (Evidence: Weak 1).
  • Assess Severity: Use VAS to quantify pain and pruritus severity for monitoring treatment efficacy (Evidence: Expert opinion 1).
  • References

    1 Mülkoğlu C, Nacır B. Notalgia paresthetica: clinical features, radiological evaluation, and a novel therapeutic option. BMC neurology 2020. link 2 Massey EW, Pleet AB. Localized pruritus-notalgia paresthetica. Archives of dermatology 1979. link 3 Massey EW, Pleet AB. Handcuffs and cheiralgia paresthetica. Neurology 1978. link

    Original source

    1. [1]
    2. [2]
      Localized pruritus-notalgia paresthetica.Massey EW, Pleet AB Archives of dermatology (1979)
    3. [3]
      Handcuffs and cheiralgia paresthetica.Massey EW, Pleet AB Neurology (1978)

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