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Harmful pattern of use of herbal medicine

Last edited: 4/14/2026

Overview

Harmful patterns of herbal medicine use encompass irrational or unsafe practices that can lead to adverse health outcomes due to lack of regulation, inadequate knowledge among healthcare providers, and inconsistent pharmacovigilance systems 23.

Diagnosis

  • Clinical Presentation: Identification of adverse events or ineffective treatment outcomes linked to herbal medicine use 2.
  • Recommended Tests: Lack of standardized diagnostic tests; reliance on patient history and clinical judgment 2.
  • Grading: No specific grading system mentioned; assessment based on severity and frequency of adverse effects 2.

    • Management

  • Education and Awareness: Enhance healthcare providers' knowledge about herbal medicine safety and efficacy 3.
  • Pharmacovigilance: Implement robust systems for monitoring adverse events related to herbal products 2.
  • Regulatory Compliance: Advocate for stricter regulatory frameworks to ensure quality and safety of herbal medicines 2.

    • Special Populations

  • Pregnancy: Limited data; caution advised due to potential teratogenic effects without rigorous safety studies 13.
  • Pediatrics: Higher risk of adverse reactions due to immature metabolism; close monitoring required 3.
  • Elderly: Increased susceptibility to drug interactions; careful evaluation of herbal supplement use recommended 3.

    • Key Recommendations

  • Strengthen Healthcare Provider Education on herbal medicine safety and rational use (Evidence: Moderate 3).
  • Enhance Pharmacovigilance Systems globally to monitor adverse events effectively (Evidence: Moderate 2).
  • Promote Regulatory Oversight of herbal products to ensure quality and safety standards (Evidence: Expert opinion 2).

    • References

    1 Ahmed MAA, Seydou A, Coulibaly I, Kielmann K, Ravinetto R. Irrational medicine use and its associated factors in conflict-affected areas in Mali: a cross-sectional study. Global health action 2025. link 2 Ekhart C, Wiarda SHP, van de Koppel S, Skalli S, Alghamdi W, Menniti-Ippolito F et al.. Qualitative Interviews with Stakeholders in Herbal Pharmacovigilance and Recommendations for Best Practices to be Applied Worldwide. Drug safety 2025. link 3 Gökkaya İ, Özceylan ÖF, Çolak B, Renda G, Duman M, Duman EN. Assessment of physicians' knowledge, thoughts, and attitudes regarding the phytovigilance system. Expert opinion on drug safety 2025. link 4 Zagórska-Dziok M, Ziemlewska A, Mokrzyńska A, Nizioł-Łukaszewska Z, Wójciak M, Sowa I. Evaluation of the Biological Activity of Hydrogel with . Molecules (Basel, Switzerland) 2023. link 5 Vander Weerdt C, Stoddard-Dare P, DeRigne L. Is paid sick leave bad for business? A systematic review. American journal of industrial medicine 2023. link 6 Krzemińska B, Dybowski MP, Klimek K, Typek R, Miazga-Karska M, Ginalska G et al.. Can Extracts from the Leaves and Fruits of the . Molecules (Basel, Switzerland) 2022. link 7 Guo L, Qi J, Du D, Liu Y, Jiang X. Current advances of . Pharmaceutical biology 2020. link 8 Yao Y, Cheng X, Ren G. A 90-day study of three bruchid-resistant mung bean cultivars in Sprague-Dawley rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2015. link 9 Kantor ED, Rehm CD, Haas JS, Chan AT, Giovannucci EL. Trends in Prescription Drug Use Among Adults in the United States From 1999-2012. JAMA 2015. link 10 Rubin GD. Computed tomography: revolutionizing the practice of medicine for 40 years. Radiology 2014. link 11 Conde C. Not ready to quit. Texas medicine 2012. link 12 . ACOG Committee Opinion No. 510: Ethical ways for physicians to market a practice. Obstetrics and gynecology 2011. link 13 Gilca M, Gaman L, Panait E, Stoian I, Atanasiu V. Chelidonium majus--an integrative review: traditional knowledge versus modern findings. Forschende Komplementarmedizin (2006) 2010. link 14 Lichter PR. CME, physicians, and Pavlov: can we change what happens when industry rings the bell?. Transactions of the American Ophthalmological Society 2008. link 15 Janes H. Competition policy: consequences of restrictive trade practices and price-fixing provisions for medical practitioners in Australia and New Zealand. Journal of law and medicine 2006. link 16 Olayemi SO, Akinyede AA, Oreagba AI. Prescription pattern at primary health care centres in Lagos State. The Nigerian postgraduate medical journal 2006. link 17 Das BP, Sethi A, Nutan K, Gunjan. Teaching exercise of drug utilization by medical students. JNMA; journal of the Nepal Medical Association 2005. link 18 Ismach RB. Teaching evidence-based medicine to medical students. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2004. link 19 . Change practice patterns without ruffling feathers. Physician relations update 1998. link 20 Giuse NB, Giuse DA, Bankowitz RA, Miller RA. Comparing contents of a knowledge base to traditional information sources. Proceedings. Symposium on Computer Applications in Medical Care 1993. link 21 Rosenthal LE. Information networks and their impact upon medicine. Annals of the Academy of Medicine, Singapore 1990. link 22 Schwartz WB, Newhouse JP, Bennett BW, Williams AP. The changing geographic distribution of board-certified physicians. The New England journal of medicine 1980. link

    Original source

    1. [1]
      Irrational medicine use and its associated factors in conflict-affected areas in Mali: a cross-sectional study. — Ahmed MAA, Seydou A, Coulibaly I, Kielmann K, Ravinetto R Global health action (2025)
    2. [2]
      Qualitative Interviews with Stakeholders in Herbal Pharmacovigilance and Recommendations for Best Practices to be Applied Worldwide. — Ekhart C, Wiarda SHP, van de Koppel S, Skalli S, Alghamdi W, Menniti-Ippolito F et al. Drug safety (2025)
    3. [3]
      Assessment of physicians' knowledge, thoughts, and attitudes regarding the phytovigilance system. — Gökkaya İ, Özceylan ÖF, Çolak B, Renda G, Duman M, Duman EN Expert opinion on drug safety (2025)
    4. [4]
      Evaluation of the Biological Activity of Hydrogel with — Zagórska-Dziok M, Ziemlewska A, Mokrzyńska A, Nizioł-Łukaszewska Z, Wójciak M, Sowa I Molecules (Basel, Switzerland) (2023)
    5. [5]
      Is paid sick leave bad for business? A systematic review. — Vander Weerdt C, Stoddard-Dare P, DeRigne L American journal of industrial medicine (2023)
    6. [6]
      Can Extracts from the Leaves and Fruits of the — Krzemińska B, Dybowski MP, Klimek K, Typek R, Miazga-Karska M, Ginalska G et al. Molecules (Basel, Switzerland) (2022)
    7. [7]
      Current advances of — Guo L, Qi J, Du D, Liu Y, Jiang X Pharmaceutical biology (2020)
    8. [8]
      A 90-day study of three bruchid-resistant mung bean cultivars in Sprague-Dawley rats. — Yao Y, Cheng X, Ren G Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (2015)
    9. [9]
      Trends in Prescription Drug Use Among Adults in the United States From 1999-2012. — Kantor ED, Rehm CD, Haas JS, Chan AT, Giovannucci EL JAMA (2015)
    10. [10]
      Computed tomography: revolutionizing the practice of medicine for 40 years. — Rubin GD Radiology (2014)
    11. [11]
      Not ready to quit. — Conde C Texas medicine (2012)
    12. [12]
      ACOG Committee Opinion No. 510: Ethical ways for physicians to market a practice. Obstetrics and gynecology (2011)
    13. [13]
      Chelidonium majus--an integrative review: traditional knowledge versus modern findings. — Gilca M, Gaman L, Panait E, Stoian I, Atanasiu V Forschende Komplementarmedizin (2006) (2010)
    14. [14]
      CME, physicians, and Pavlov: can we change what happens when industry rings the bell? — Lichter PR Transactions of the American Ophthalmological Society (2008)
    15. [15]
      Competition policy: consequences of restrictive trade practices and price-fixing provisions for medical practitioners in Australia and New Zealand. — Janes H Journal of law and medicine (2006)
    16. [16]
      Prescription pattern at primary health care centres in Lagos State. — Olayemi SO, Akinyede AA, Oreagba AI The Nigerian postgraduate medical journal (2006)
    17. [17]
      Teaching exercise of drug utilization by medical students. — Das BP, Sethi A, Nutan K, Gunjan JNMA; journal of the Nepal Medical Association (2005)
    18. [18]
      Teaching evidence-based medicine to medical students. — Ismach RB Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2004)
    19. [19]
      Change practice patterns without ruffling feathers. Physician relations update (1998)
    20. [20]
      Comparing contents of a knowledge base to traditional information sources. — Giuse NB, Giuse DA, Bankowitz RA, Miller RA Proceedings. Symposium on Computer Applications in Medical Care (1993)
    21. [21]
      Information networks and their impact upon medicine. — Rosenthal LE Annals of the Academy of Medicine, Singapore (1990)
    22. [22]
      The changing geographic distribution of board-certified physicians. — Schwartz WB, Newhouse JP, Bennett BW, Williams AP The New England journal of medicine (1980)
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