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Pathological fracture - ankle and/or foot

Last edited: 4/10/2026

Overview

A pathological fracture occurs when a bone breaks at a site weakened by disease, such as a tumor or metabolic bone disorder 1. In the ankle and foot, these fractures can arise from underlying conditions that compromise bone integrity, leading to instability and pain 1.

Diagnosis

  • Diagnosis is based on clinical presentation and imaging, with suspicion raised by the mechanism of injury relative to the fracture severity 1.
  • Radiographs are the primary imaging modality 1.
  • Further investigations may include bone density scans or biopsy to identify underlying pathology 1.
  • Management

  • Management is guided by the underlying cause of the pathological fracture 1.
  • Treatment aims to stabilize the fracture, manage pain, and address the underlying pathology 1.
  • Surgical intervention may be required for stabilization, especially in weight-bearing bones 1.
  • Pain management strategies are crucial, involving multimodal approaches 1.
  • Key Recommendations

  • Assess postsurgical opioid use risk preoperatively 1.
  • Opioid-naïve patients should not start opioids preoperatively unless non-opioid multimodal analgesia fails 1.
  • If opioids are prescribed at discharge, patients should receive clear instructions 1.
  • References

    1 Dillane D, Ramadi A, Nathanail S, Dick BD, Bostick G, Chan K et al.. Elective surgery in ankle and foot disorders-best practices for management of pain: a guideline for clinicians. Canadian journal of anaesthesia = Journal canadien d'anesthesie 2022. link

    Original source

    1. [1]
      Elective surgery in ankle and foot disorders-best practices for management of pain: a guideline for clinicians.Dillane D, Ramadi A, Nathanail S, Dick BD, Bostick G, Chan K et al. Canadian journal of anaesthesia = Journal canadien d'anesthesie (2022)

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