Pathophysiology
Microscopic analysis revealed dense infiltration of the entire skin graft by Dupuytren disease, indicating that the condition may extend beyond the fascial layers into the grafted skin [PMID:27282210].
Clinical Presentation
The case study highlights typical clinical features such as cold-induced digital pain, recurrent digital ulcers, hand swelling, and impaired fine motor function in a patient with limited cutaneous systemic sclerosis [PMID:41874407].
Management
A structured neurofascialvascular training programme, including supervised sessions followed by home practice, led to significant improvements in Raynaud's symptoms, hand mobility, and disability scores in a patient with limited cutaneous systemic sclerosis [PMID:41874407].
A patient required revision dermofasciectomy and FTSG two decades after the initial procedure due to recurrent disease affecting the grafted area [PMID:27282210].
Complications
The case demonstrated fibromatosis within the graft, differentiated from hypertrophic scarring, highlighting potential complications in long-term management [PMID:27282210].
Prognosis & Follow-up
Post-intervention improvements in hand function and reduction in Raynaud's episodes were largely sustained through follow-up with a home-only training programme, indicating sustained benefits [PMID:41874407].
References
1 Bertacchini P. Neurofascialvascular training in systemic sclerosis: Clinical outcomes, proposed rationale, and home-programme feasibility. Modern rheumatology case reports 2026. link 2 Wade RG, Igali L, Figus A. Dupuytren Disease Infiltrating a Full-Thickness Skin Graft. The Journal of hand surgery 2016. link
2 papers cited of 3 indexed.