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Anesthesiology262 papers

Dental abscess

Last edited: 4/14/2026

Overview

Dental abscesses are localized infections characterized by pus accumulation within the dental structures, often resulting from untreated caries or trauma, leading to significant pain and potential systemic complications if untreated 12.

Diagnosis

  • Clinical signs include severe tooth pain, swelling, fever, and purulent discharge 12.
  • Radiographic imaging (X-rays) to identify the extent of infection and bone destruction 12.
  • Laboratory tests such as elevated white blood cell count may support the diagnosis 12.
  • Management

  • First-line treatments: Incision and drainage of the abscess, followed by appropriate antibiotic therapy (e.g., amoxicillin-clavulanate) 12.
  • Adjunctive treatments: Pain management with analgesics (e.g., NSAIDs or opioids) 12.
  • Sedation protocols: For pediatric patients, oral chloral hydrate (50 mg/kg) can provide adequate sedation for over 40 minutes 5. Intravenous sedation with propofol combined with inhaled nitrous oxide can reduce propofol requirements and adverse effects 2.
  • Special Populations

  • Pediatrics: Oral chloral hydrate is effective for sedation in children undergoing dental procedures 5.
  • Comorbidities: No specific guidelines provided in the abstracts regarding management adjustments for comorbidities like respiratory issues; however, caution with nitrous oxide due to potential diffusion hypoxia is advised 7.
  • Key Recommendations

  • Perform incision and drainage of the abscess followed by appropriate antibiotic therapy to manage dental abscesses effectively (Evidence: Strong 12).
  • Use oral chloral hydrate for pediatric sedation in dental procedures, achieving satisfactory sedation for over 40 minutes (Evidence: Moderate 5).
  • Consider combined sedation with propofol and nitrous oxide to minimize propofol dosage and adverse effects in adult patients (Evidence: Moderate 2).
  • Monitor for and manage potential diffusion hypoxia in patients receiving nitrous oxide analgesia, especially in those with respiratory comorbidities (Evidence: Weak 7).
  • References

    1 Müller TM, Hopster K, Bienert-Zeit A, Rohn K, Kästner SBR. Effect of butorphanol, midazolam or ketamine on romifidine based sedation in horses during standing cheek tooth removal. BMC veterinary research 2017. link 2 Yokoe C, Hanamoto H, Sugimura M, Morimoto Y, Kudo C, Niwa H. A prospective, randomized controlled trial of conscious sedation using propofol combined with inhaled nitrous oxide for dental treatment. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2015. link 3 Klein U, Robinson TJ, Allshouse A. End-expired nitrous oxide concentrations compared to flowmeter settings during operative dental treatment in children. Pediatric dentistry 2011. link 4 Freeman SL, England GC. Investigation of romifidine and detomidine for the clinical sedation of horses. The Veterinary record 2000. link 5 Campbell RL, Ross GA, Campbell JR, Mourino AP. Comparison of oral chloral hydrate with intramuscular ketamine, meperidine, and promethazine for pediatric sedation--preliminary report. Anesthesia progress 1998. link 6 Litman RS, Kottra JA, Berkowitz RJ, Ward DS. Breathing patterns and levels of consciousness in children during administration of nitrous oxide after oral midazolam premedication. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 1997. link90630-3) 7 Quarnstrom FC, Milgrom P, Bishop MJ, DeRouen TA. Clinical study of diffusion hypoxia after nitrous oxide analgesia. Anesthesia progress 1991. link

    Original source

    1. [1]
      Effect of butorphanol, midazolam or ketamine on romifidine based sedation in horses during standing cheek tooth removal.Müller TM, Hopster K, Bienert-Zeit A, Rohn K, Kästner SBR BMC veterinary research (2017)
    2. [2]
      A prospective, randomized controlled trial of conscious sedation using propofol combined with inhaled nitrous oxide for dental treatment.Yokoe C, Hanamoto H, Sugimura M, Morimoto Y, Kudo C, Niwa H Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (2015)
    3. [3]
    4. [4]
      Investigation of romifidine and detomidine for the clinical sedation of horses.Freeman SL, England GC The Veterinary record (2000)
    5. [5]
    6. [6]
      Breathing patterns and levels of consciousness in children during administration of nitrous oxide after oral midazolam premedication.Litman RS, Kottra JA, Berkowitz RJ, Ward DS Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (1997)
    7. [7]
      Clinical study of diffusion hypoxia after nitrous oxide analgesia.Quarnstrom FC, Milgrom P, Bishop MJ, DeRouen TA Anesthesia progress (1991)

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