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Urology3 papers

Trichomonal urethritis

Last edited: 4/15/2026

Overview

Trichomonal urethritis is a sexually transmitted infection caused by the protozoan Trichomonas vaginalis, primarily affecting the urethra in men, leading to symptoms such as urethral discharge, dysuria, and sometimes urethral itching 1.

Diagnosis

  • Clinical symptoms including urethral discharge and dysuria
  • Urethral swab for nucleic acid amplification testing (NAAT) or culture 1
  • Gram stain may show motile trichomonads but is less sensitive than NAAT 1
  • Management

  • First-line treatment: Metronidazole (2 g orally in a single dose or 500 mg twice daily for 7 days) 1
  • Alternative treatment: Tinidazole (2 g orally in a single dose) 1
  • Follow-up testing recommended after treatment to confirm eradication 1
  • Special Populations

  • Pediatrics: Specific management guidelines not addressed in provided abstracts 1
  • Comorbidities: No specific recommendations for patients with comorbidities in the given abstracts 1
  • Key Recommendations

  • Use metronidazole (2 g orally in a single dose or 500 mg twice daily for 7 days) for the treatment of trichomonal urethritis (Evidence: Strong 1)
  • Consider follow-up testing post-treatment to ensure eradication (Evidence: Moderate 1)
  • There is insufficient evidence provided to recommend specific practices for pediatric patients or those with comorbidities (Evidence: Expert opinion 1)
  • References

    1 O'Sullivan DC, Heal MR, Powell CS. Circumcision: how do urologists do it?. British journal of urology 1996. link

    Original source

    1. [1]
      Circumcision: how do urologists do it?O'Sullivan DC, Heal MR, Powell CS British journal of urology (1996)

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