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Otolaryngology (ENT)31 papers

Subglottic lesion

Last edited: 4/15/2026

Overview

Subglottic hemangioma is a rare, benign congenital vascular tumor that typically obstructs the airway, leading to respiratory distress, especially in infants within the first six months of life. Symptoms often resolve spontaneously over time, but early intervention is crucial to prevent mortality 1.

Diagnosis

  • Characteristic biphasic stridor due to subglottic obstruction
  • Typically presents in the first six months of life
  • Diagnosis confirmed via flexible laryngoscopy and imaging (e.g., laryngotracheobronchoscopy) 1
  • Management

  • First-line treatment: Endoscopic CO2 laser surgery for airway restoration 1
  • Adjunctive treatments: Medications such as corticosteroids to reduce lesion size (specific dosing not detailed in abstract) 1
  • Special Populations

  • Pediatrics: High incidence of airway obstruction in infants; early intervention critical 1
  • Key Recommendations

  • Immediate therapeutic intervention is necessary to restore normal respiration and prevent mortality in cases of subglottic hemangioma 1 (Evidence: Strong)
  • Endoscopic CO2 laser surgery is recommended for managing airway obstruction in pediatric patients with subglottic hemangioma 1 (Evidence: Moderate)
  • Consider adjunctive corticosteroid therapy to aid in reducing lesion size and improving symptoms 1 (Evidence: Weak)
  • References

    1 Re M, Forte V, Berardi C, Mallardi V. Role of endoscopic CO2 laser surgery in the treatment of congenital infantile subglottic hemangioma. Experience in the Department of Otolaryngology, "Sick Children Hospital", Toronto, Canada. Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 2003. link

    Original source

    1. [1]
      Role of endoscopic CO2 laser surgery in the treatment of congenital infantile subglottic hemangioma. Experience in the Department of Otolaryngology, "Sick Children Hospital", Toronto, Canada.Re M, Forte V, Berardi C, Mallardi V Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale (2003)

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