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Obstetrics72 papers

Infection of uterus

Last edited: 4/10/2026

Overview

Uterine infection, also known as endometritis, is an inflammation of the inner lining of the uterus (endometrium). It can occur after childbirth, gynecological procedures, or as a complication of other infections.

Diagnosis

  • Diagnosis is typically based on clinical symptoms and physical examination.
  • Symptoms may include fever, lower abdominal pain, uterine tenderness, and abnormal vaginal discharge 1.
  • Laboratory tests such as complete blood count and inflammatory markers may be used.
  • Cultures of vaginal or cervical discharge can help identify the causative organism.
  • Management

  • Treatment involves antibiotics to target the likely bacterial pathogens.
  • Commonly used antibiotic regimens include clindamycin and gentamicin, often given intravenously 1.
  • Surgical intervention may be considered in severe or refractory cases.
  • Special Populations

  • Pregnancy: Endometritis is a common complication following childbirth (postpartum endometritis) and can also occur during pregnancy. Prompt diagnosis and treatment are crucial to prevent maternal and fetal complications 1.
  • Key Recommendations

  • Treatment of uterine infection typically involves broad-spectrum antibiotics targeting common pathogens 1.
  • In postpartum endometritis, intravenous clindamycin and gentamicin are frequently recommended 1.
  • Prompt diagnosis and management are essential to prevent complications, particularly in pregnant individuals 1.
  • References

    1 Fernandes I, Rodrigues CIS, Korkes HA, de Sampaio LF. Problem-based learning in obstetrics and gynecology: a systematic review. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 2025. link

    Original source

    1. [1]
      Problem-based learning in obstetrics and gynecology: a systematic review.Fernandes I, Rodrigues CIS, Korkes HA, de Sampaio LF Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia (2025)

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