Overview
Anal inflammation encompasses various inflammatory conditions affecting the anal region, often involving the rectum and perianal tissues. It can result from infectious, autoimmune, or idiopathic causes and is characterized by symptoms such as pain, swelling, and discharge. 123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081Diagnosis
Management
References
Showing 100 most recent of 352 indexed papers.
1 Huang Q, Luo Y, Chen Q, Cui Y. MALT1 Knockdown Alleviates Multiorgan Injury and Inflammation Through Inhibiting TAK1/NF-κB Signaling Pathway-Mediated T-Helper 1 and 17 Differentiations in LPS-induced Inflammation. Inflammation 2026. link 2 Garbizu M, Mocha-Muñoz N, Rubio-López E, Palacios L, Aguado L, Ardaya M et al.. Longitudinal imaging evaluation of the inflammatory role of purinergic A. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026. link 3 Hong A, Vollett KDW, Zhou YQ, Cheng HM. Molecular Magnetic Resonance Imaging Visualizes Nitric Oxide Dynamics in a Mouse Model of Acute Myocardial Inflammation. ACS sensors 2026. link 4 Abdelall EKA, Lamie PF, Labib MB, El-Daly M, Mishrif A. Synthesis and in silico studies of novel thiophene-celecoxib hybrid with excellent cardiotoxicity and nephrotoxicity safety profiles. 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Performance evaluation of alternate ESR measurement method using BC-780 automated hematology analyzer: a comparison study with the Westergren reference method. Clinical chemistry and laboratory medicine 2024. link 10 Dash S, Singh PA, Bajwa N, Choudhury A, Bisht P, Sharma R. Why Pharmacovigilance of Non-steroidal Anti-inflammatory Drugs is Important in India?. Endocrine, metabolic & immune disorders drug targets 2024. link 11 Spotts PH, Zhou F. Myocarditis and Pericarditis. Primary care 2024. link 12 Boncler M, Bartczak K, Rozalski M. Potential for modulation of platelet function via adenosine receptors during inflammation. British journal of pharmacology 2024. link 13 Wang HY, Lin X, Huang GG, Zhou R, Lei SY, Ren J et al.. Atranorin inhibits NLRP3 inflammasome activation by targeting ASC and protects NLRP3 inflammasome-driven diseases. Acta pharmacologica Sinica 2023. link 14 Laird E, O'Halloran AM, Molloy AM, Healy M, Bourke N, Kenny RA. Vitamin D status & associations with inflammation in older adults. PloS one 2023. link 15 Yakout SM, Alfadul H, Ansari MGA, Khattak MNK, Al-Daghri NM. Vitamin D Status Modestly Regulates NOD-Like Receptor Family with a Pyrin Domain 3 Inflammasome and Interleukin Profiles among Arab Adults. International journal of molecular sciences 2023. link 16 Alfawara MS, Ahmed AI, Saad JM, Han Y, Alahdab F, Al Rifai M et al.. The utility of beta-hydroxybutyrate in detecting myocardial glucose uptake suppression in patients undergoing inflammatory [18F]-FDG PET studies. European journal of nuclear medicine and molecular imaging 2023. link 17 Dong L, Xia S, Sun B, Ma L, Chen X, Wei S et al.. Potential value and mechanism of . Human & experimental toxicology 2022. link 18 Benfante R. Special Issue: Cholinergic Control of Inflammation. International journal of molecular sciences 2022. link 19 Piva E, Stoppa A, Pelloso M, Plebani M. The VES-Matic 5 system: performance of a novel instrument for measuring erythrocyte sedimentation rate. Clinical chemistry and laboratory medicine 2022. link 20 Chen X, Huang C, Zhong W, Qi S, Huang T, Yang Z. Consistency Analysis of 3 Detection Systems for Measuring Serum C-Reactive Protein. Medical science monitor : international medical journal of experimental and clinical research 2022. link 21 Zhu H, Huang Z, Huang H, Wang C, Wu L, Lin R et al.. Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes. Journal of visualized experiments : JoVE 2022. link 22 Sinha G. Doubt cast on inflammation's stop signals. Science (New York, N.Y.) 2022. link 23 Kerr AW, Efron PA, Larson SD, Rincon JC. T-Cell Activation and LPS: A Dangerous Duo for Organ Dysfunction. Journal of leukocyte biology 2022. link 24 Taylor MD, Fernandes TD, Yaipen O, Higgins CE, Capone CA, Leisman DE et al.. T cell activation and IFNγ modulate organ dysfunction in LPS-mediated inflammation. Journal of leukocyte biology 2022. link 25 Bekassy Z, Lopatko Fagerström I, Bader M, Karpman D. Crosstalk between the renin-angiotensin, complement and kallikrein-kinin systems in inflammation. Nature reviews. Immunology 2022. link 26 Cao N, Wang JJ, Wu JM, Xu WL, Wang R, Chen XD et al.. Glibenclamide alleviates β adrenergic receptor activation-induced cardiac inflammation. Acta pharmacologica Sinica 2022. link 27 Feijóo-Bandín S, Aragón-Herrera A, Otero-Santiago M, Anido-Varela L, Moraña-Fernández S, Tarazón E et al.. Role of Sodium-Glucose Co-Transporter 2 Inhibitors in the Regulation of Inflammatory Processes in Animal Models. International journal of molecular sciences 2022. link 28 Lenoir C, Rodieux F, Desmeules JA, Rollason V, Samer CF. Impact of Inflammation on Cytochromes P450 Activity in Pediatrics: A Systematic Review. Clinical pharmacokinetics 2021. link 29 Chu SAA, Stokol T. Assay variability and storage stability of the myeloperoxidase index of the ADVIA 2120i hematology analyzer in canine and equine whole blood samples. Veterinary clinical pathology 2021. link 30 Galvão I, Melo EM, de Oliveira VLS, Vago JP, Queiroz-Junior C, de Gaetano M et al.. Therapeutic potential of the FPR2/ALX agonist AT-01-KG in the resolution of articular inflammation. Pharmacological research 2021. link 31 Zhang X, Hu L, Xu S, Ye C, Chen A. Erianin: A Direct NLRP3 Inhibitor With Remarkable Anti-Inflammatory Activity. Frontiers in immunology 2021. link 32 Kobayashi Y. Current Trends of Neutrophil Biology. International journal of molecular sciences 2020. link 33 Lapić I, Miloš M, Tosato F, Piva E, Zadro R, Rogić D et al.. Analytical validation of the iSED automated analyzer for erythrocyte sedimentation rate. International journal of laboratory hematology 2020. link 34 Ha VT, Lainšček D, Gesslbauer B, Jarc-Jovičić E, Hyötyläinen T, Ilc N et al.. Synergy between 15-lipoxygenase and secreted PLA. Proceedings of the National Academy of Sciences of the United States of America 2020. link 35 Galvão I, de Carvalho RVH, Vago JP, Silva ALN, Carvalho TG, Antunes MM et al.. The role of annexin A1 in the modulation of the NLRP3 inflammasome. Immunology 2020. link 36 Hughes D, Vlahovich N, Welvaert M, Tee N, Harcourt P, White S et al.. Glucocorticoid prescribing habits of sports medicine physicians working in high-performance sport: a 30-nation survey. British journal of sports medicine 2020. link 37 Yang D, Li S, Duan X, Ren J, Liang S, Yakoumatos L et al.. TLR4 induced Wnt3a-Dvl3 restrains the intensity of inflammation and protects against endotoxin-driven organ failure through GSK3β/β-catenin signaling. Molecular immunology 2020. link 38 Shields GS, Spahr CM, Slavich GM. Psychosocial Interventions and Immune System Function: A Systematic Review and Meta-analysis of Randomized Clinical Trials. JAMA psychiatry 2020. link 39 Wechalekar K. Stop that glucose getting to heart!. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2020. link 40 Lapić I, Piva E, Spolaore F, Tosato F, Pelloso M, Plebani M. Automated measurement of the erythrocyte sedimentation rate: method validation and comparison. Clinical chemistry and laboratory medicine 2019. link 41 Lapić I, Piva E, Spolaore F, Musso G, Tosato F, Pelloso M et al.. Ves-Matic CUBE 200: is modified Westergren method for erythrocyte sedimentation rate a valid alternative to the gold standard?. Journal of clinical pathology 2019. link 42 Xiang D, Yue J, Liu P, Sun J, Ren S, Sha C et al.. Immunoturbidimetric Assay for Determination of Peripheral Blood C Reactive Protein on the Pentra MS CRP Hematology Analyzer. Clinical laboratory 2019. link 43 Mouasni S, Gonzalez V, Schmitt A, Bennana E, Guillonneau F, Mistou S et al.. The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding. Cell death & disease 2019. link 44 Wu J, Luo Y, Jiang Q, Li S, Huang W, Xiang L et al.. Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1. Pharmacological research 2019. link 45 Demaria M, Barry A, Murphy K. Using Inquiry-Based Learning to Enhance Immunology Laboratory Skills. Frontiers in immunology 2019. link 46 Munasinghe LL, Ekwaru JP, Mastroeni MF, Mastroeni SSBS, Veugelers PJ. The association of serum 25-hydroxyvitamin D concentrations with elevated serum ferritin levels in normal weight, overweight and obese Canadians. PloS one 2019. link 47 Munasinghe LL, Ekwaru JP, Mastroeni SSBS, Mastroeni MF, Veugelers PJ. The Effect of Serum 25-Hydroxyvitamin D on Serum Ferritin Concentrations: A Longitudinal Study of Participants of a Preventive Health Program. Nutrients 2019. link 48 Tuuminen T, Sorsa M, Tornudd M, Poussa T, Antila E, Jaakkola K. The association between high sensitivity C-reactive protein and micronutrient levels: A cross-sectional analysis based on a laboratory database. Clinical nutrition ESPEN 2019. link 49 Linke B, Meyer Dos Santos S, Picard-Willems B, Keese M, Harder S, Geisslinger G et al.. CXCL16/CXCR6-mediated adhesion of human peripheral blood mononuclear cells to inflamed endothelium. Cytokine 2019. link 50 Ceri A, Pavic M, Horvat I, Radic Antolic M, Zadro R. Development and validation of a rapid method for genotyping three P-selectin gene polymorphisms based on high resolution melting analysis. Journal of clinical laboratory analysis 2019. link 51 Taghizadeh M, Hamedifard Z, Jafarnejad S. Effect of garlic supplementation on serum C-reactive protein level: A systematic review and meta-analysis of randomized controlled trials. Phytotherapy research : PTR 2019. link 52 Huang L, Chen Q, Yu L, Bai D. Pyropheophorbide-α methyl ester-mediated photodynamic therapy induces apoptosis and inhibits LPS-induced inflammation in RAW264.7 macrophages. Photodiagnosis and photodynamic therapy 2019. link 53 Moerke C, Jaco I, Dewitz C, Müller T, Jacobsen AV, Gautheron J et al.. The anticonvulsive Phenhydan. Cell death and differentiation 2019. link 54 Shin D, Lee KW, Brann L, Shivappa N, Hébert JR. Dietary inflammatory index is positively associated with serum high-sensitivity C-reactive protein in a Korean adult population. Nutrition (Burbank, Los Angeles County, Calif.) 2019. link 55 Garrote BL, Fernandes FCB, Cilli EM, Bueno PR. Field effect in molecule-gated switches and the role of target-to-receptor size ratio in biosensor sensitivity. Biosensors & bioelectronics 2019. link 56 Liu X, Niu Y, Zhang X, Zhang Y, Yu Y, Huang J et al.. Recombinant . Analytical cellular pathology (Amsterdam) 2019. link 57 Rosenberg JF, Wellehan JFX, Crevasse SE, Cray C, Stacy NI. REFERENCE INTERVALS FOR ERYTHROCYTE SEDIMENTATION RATE, LACTATE, FIBRINOGEN, HEMATOLOGY, AND PLASMA PROTEIN ELECTROPHORESIS IN CLINICALLY HEALTHY CAPTIVE GOPHER TORTOISES ( GOPHERUS POLYPHEMUS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 2018. link 58 He H, Jiang H, Chen Y, Ye J, Wang A, Wang C et al.. Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity. Nature communications 2018. link 59 Schmeer KK, Tarrence J. Racial-ethnic Disparities in Inflammation: Evidence of Weathering in Childhood?. Journal of health and social behavior 2018. link 60 Varela ML, Mogildea M, Moreno I, Lopes A. Acute Inflammation and Metabolism. Inflammation 2018. link 61 Sarangi PP, Lee HW, Lerman YV, Trzeciak A, Harrower EJ, Rezaie AR et al.. Activated Protein C Attenuates Severe Inflammation by Targeting VLA-3. Journal of immunology (Baltimore, Md. : 1950) 2017. link 62 Gorman S, Buckley AG, Ling KM, Berry LJ, Fear VS, Stick SM et al.. Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrity. Physiological reports 2017. link 63 Gundra UM, Girgis NM, Gonzalez MA, San Tang M, Van Der Zande HJP, Lin JD et al.. Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation. Nature immunology 2017. link 64 Kokotou MG, Limnios D, Nikolaou A, Psarra A, Kokotos G. Inhibitors of phospholipase A. Expert opinion on therapeutic patents 2017. link 65 Osborne MT, Hulten EA, Murthy VL, Skali H, Taqueti VR, Dorbala S et al.. Patient preparation for cardiac fluorine-18 fluorodeoxyglucose positron emission tomography imaging of inflammation. 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Hepatology (Baltimore, Md.) 2017. link 71 Nydegger U, Lung T, Risch L, Risch M, Medina Escobar P, Bodmer T. Inflammation Thread Runs across Medical Laboratory Specialities. Mediators of inflammation 2016. link 72 Van de Water E, Oosterlinck M, Duchateau L, Pille F. Agreement of manual cell counts and automated counts of the scil Vet abc Plus(+) hematology analyzer for analysis of equine synovial fluid. Research in veterinary science 2016. link 73 Hahn J, Knopf J, Maueröder C, Kienhöfer D, Leppkes M, Herrmann M. Neutrophils and neutrophil extracellular traps orchestrate initiation and resolution of inflammation. Clinical and experimental rheumatology 2016. link 74 Franklin BS, Mangan MS, Latz E. Crystal Formation in Inflammation. Annual review of immunology 2016. link 75 Fitch K. Glucocorticoids at the Olympic Games: state-of-the-art review. British journal of sports medicine 2016. link 76 Cavaillon JM, Legout S. Centenary of the death of Elie Metchnikoff: a visionary and an outstanding team leader. Microbes and infection 2016. link 77 Schmid-Schönbein GW. The autodigestion hypothesis: Proteolytic receptor cleavage in rheological and cardiovascular cell dysfunction1. Biorheology 2016. link 78 de Jong PR, González-Navajas JM, Jansen NJ. The digestive tract as the origin of systemic inflammation. Critical care (London, England) 2016. link 79 Wu P, Jiang WD, Jiang J, Zhao J, Liu Y, Zhang YA et al.. Dietary choline deficiency and excess induced intestinal inflammation and alteration of intestinal tight junction protein transcription potentially by modulating NF-κB, STAT and p38 MAPK signaling molecules in juvenile Jian carp. Fish & shellfish immunology 2016. link 80 Mousa A, Misso M, Teede H, Scragg R, de Courten B. Effect of vitamin D supplementation on inflammation: protocol for a systematic review. BMJ open 2016. link 81 Pelekanou V, Kampa M, Kiagiadaki F, Deli A, Theodoropoulos P, Agrogiannis G et al.. Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ERα36 and GPR30/GPER1. Journal of leukocyte biology 2016. link 82 Rocha DM, Caldas AP, Oliveira LL, Bressan J, Hermsdorff HH. Saturated fatty acids trigger TLR4-mediated inflammatory response. Atherosclerosis 2016. link 83 Yang Y, Lv J, Jiang S, Ma Z, Wang D, Hu W et al.. The emerging role of Toll-like receptor 4 in myocardial inflammation. Cell death & disease 2016. link 84 Nomura N, Saito K, Ikeda M, Yuasa S, Pastore M, Chabert C et al.. Evaluation of the Microsemi CRP, an automated hematology analyzer for rapid 3-part WBC differential and CRP using whole blood. International journal of laboratory hematology 2015. link 85 Zimmermann M, Steenhuis P, Linssen J, Weimann A. Detection and quantification of hypo- and hypergranulated neutrophils on the new Sysmex XN hematology analyzer: establishment of an adapted reference interval for the neutrophil-granularity-intensity compared to XE-technology in adult patients. Clinical laboratory 2015. link 86 Bergmann KR, Kharbanda A, Haveman L. Myocarditis And Pericarditis In The Pediatric Patient: Validated Management Strategies. Pediatric emergency medicine practice 2015. link 87 Rocha J, Eduardo-Figueira M, Barateiro A, Fernandes A, Brites D, Bronze R et al.. Anti-inflammatory effect of rosmarinic acid and an extract of Rosmarinus officinalis in rat models of local and systemic inflammation. Basic & clinical pharmacology & toxicology 2015. link 88 van Stijn CM, Kim J, Lusis AJ, Barish GD, Tangirala RK. Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response. 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Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies* 2014. link 93 Fuchs B. Mass spectrometry and inflammation--MS methods to study oxidation and enzyme-induced changes of phospholipids. Analytical and bioanalytical chemistry 2014. link 94 Barbosa-Leiker C, Roper V, McPherson S, Lei M, Wright B, Hoekstra T et al.. Cross-sectional and longitudinal relationships between perceived stress and C-reactive protein in men and women. Stress and health : journal of the International Society for the Investigation of Stress 2014. link 95 García-Rodríguez RV, Gutiérrez-Rebolledo GA, Méndez-Bolaina E, Sánchez-Medina A, Maldonado-Saavedra O, Domínguez-Ortiz MÁ et al.. Cnidoscolus chayamansa Mc Vaugh, an important antioxidant, anti-inflammatory and cardioprotective plant used in Mexico. Journal of ethnopharmacology 2014. link 96 Raaz-Schrauder D, Ekici AB, Klinghammer L, Stumpf C, Achenbach S, Herrmann M et al.. The proinflammatory effect of C-reactive protein on human endothelial cells depends on the FcγRIIa genotype. Thrombosis research 2014. link 97 Artero EG, España-Romero V, Jiménez-Pavón D, Martinez-Gómez D, Warnberg J, Gómez-Martínez S et al.. Muscular fitness, fatness and inflammatory biomarkers in adolescents. Pediatric obesity 2014. link 98 Adam M, Gajdova S, Kolarova H, Kubala L, Lau D, Geisler A et al.. Red blood cells serve as intravascular carriers of myeloperoxidase. Journal of molecular and cellular cardiology 2014. link 99 Ward PA. The bipolar role of miR-466l in inflammation. Immunity 2013. link 100 Pino CJ, Yevzlin AS, Lee K, Westover AJ, Smith PL, Buffington DA et al.. Cell-based approaches for the treatment of systemic inflammation. 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